Last Update Date
03.04.2025

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Every woman wants to feel the maternity. We try to see smiling on your face for that very small breath to be included into your world. We, as Huma IVF Center, plan to be with you in this process from the first step of your treatment to your birth with awareness of your infertility problems. We target to bring you together with the healthy individuals in your home while starting with the slogan ‘Let us Add Your Imagination into Your Life’, believe that you will feel safe and in peace in our center. We take the fair pride in presenting the high quality service to you with a principle trying to catch the world standards with our knowledge.


WHY IS HUMA IVF CENTER?
Our success in the assisted reproductive treatments is based on a team working in plan and in coordination.
Our team consisted of the gynaecologists, embryologists, nurses and the patient consultants expert at their subjects, open to share information shall be glad to give service to you in this way where you started in order to be able to have a child.
Huma IVF Center started out by making renewing itself every passing day in the infertility practices a rule. We are over the world standards at rates of pregnancy to be obtained by using the assisted reproductive techniques.
Our patient consultants are in your service in all stages of your treatments in order to ease the IVF center treatment processes of our patients who will come to our center for treatment from abroad. We enable accommodation at a discount in our contractual hotels and the transportation support, prepare the programs where you will be able to follow your treatment at a distance.

IVF Center Treatment Techniques

• TESE- TESA Practices
• PGT (Pre-implantation Genetic Diagnostic)
• Calcium Ionophore
• Intra lipid
• Asisted Hatching
• Microchip
• Embryoscopy
• Pool Method
• Uterus Resting
• PRP

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PREIMPLANTATION GENETIC DIAGNOSIS
In recent years, developments in genetics allow genetic analysis to be carried out on embryos developed in vitro by in vitro fertilization  ethods and the placement of selected healthy embryos in the uterus of the mother before pregnancy occurs. This method is called pre- regnancy genetic diagnosis (Preimplantation Genetic Diagnosis-PGD).
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One of the most important application areas of the PGT technique embryos that do not have a genetic disease but may not have a genetic disorder in their chromosomes.
These disorders are more common in women of advanced age (35 years and older). This situation may result in infertility as it both reduces the chance of attachment of the embryo (implantation) and may cause unwanted abortions. As a matter of fact, 40 out of every 100 pregnancies in women aged 39 and over have problems that occur due to a numerical chromosomal disorder
 
The aim of PGD is to increase implantation rates, reduce spontaneous abortions and increase healthy baby birth rates by selecting hromosomally normal embryos. Indeed, the miscarriage rate, which can reach up to 23 percent in normal pregnancy due to chromosomal disorders, may decrease to 9 percent after PGD.
 
Pre-pregnancy genetic diagnosis is performed by taking 1 or 2 cells from embryos developed as a result of fertilization of egg and sperm cells obtained from mother and father candidates in laboratory environment. Special methods called Fluorescence In Situ Hybridization (FISH), Microarray-based comparative genomic hybridization (aCGH) or Polymerase Chain Reaction (PCR) are used for genetic diagnosis. Diagnosis of numerical chromosomal disorders such as monosomy or trisomy (Down syndrome and other trisomies) and single gene diseases (such as hemophilia, Mediterranean anemia, cystic fibrosis, muscular dystrophies) in the baby to be born is possible with PGD. Thus, healthy babies are born by transferring disease-free, healthy embryos to the expectant mother.
 
DIAGNOSIS BEFORE PREGNANCY
 
  • In couples with a genetic or hereditary disease carrier,
  • In couples who have a child or children with a previous genetic disease,
  • For the purpose of HLA genotyping (tissue typing),
  • In the identification of diseases showing genetic predisposition (tendency)
  • Women in the advanced age group (37 years and over) who have been accepted for assisted reproductive techniques,
  • In couples with recurrent early pregnancy miscarriages,
  • In couples who could not achieve pregnancy with assisted reproductive techniques despite multiple applications or who lost their pregnancy due to miscarriage,
  • It is applied in cases of chromosomal disorders or genetic diseases associated with severe male infertility.
 
HOW IS THE PGT TEST DONE?
 
  • Whether the patient is suitable for PGD is evaluated by the reproductive health specialist, genetic counselor and the doctor of the related disease.
  • The couple is prepared for the IVF procedure.
  • The egg taken from the mother is fertilized in the laboratory with the sperm taken from the father.
  • 1-2 blastomere cells are removed from the obtained embryo by biopsy by embryologists
  • Cells obtained by biopsy are prepared and tested according to the method to be applied.
  • Embryos with genetic diseases or chromosomal disorders are selected and discarded and healthy embryos are transferred to the mothers womb.

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It is a method of activating eggs and ensuring fertilization by using calcium ionophore (calcium ionophore) in cases where embryo transfer cannot be performed due to lack of fertilization during IVF treatment.
 
In the calcium ionophore application, first the egg and sperm are fertilized by micro-injection (ICSI); Then the eggs are kept in a medium containing calcium ionophore for a while. The main purpose here is to artificially increase the calcium level, which should increase in the egg after the sperm enters the egg. In other words, by supporting the reactions that should start in the egg, the egg is forced to be fertilized. With this procedure, a healthy fertilization and therefore a high pregnancy rate can be achieved.
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Calcium ionophore therapy has been shown to be successful in the following situations:

  • In patients with “globosperm” of all sperms
  • If very few eggs or sperm are obtained
  • Recurrent fertilization (fertilization) failures
  • In cases where no fertilization can be achieved with micro-injection therapy

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Embryo pool technique is the method of freezing the embryos obtained by collecting two or more eggs (OPU) and transferring the accumulated embryos by thawing them together. It is possible to make an embryo pool by collecting eggs multiple times using little medication (seminatural cycle) or without using drugs (natural cycle) and transferring embryos that have reached advanced developmental stages, such as blastocyst stage. This application is recommended for couples with reduced egg reserve or concomitant IVF failures. With the embryo pool method, it will be possible to achieve more treatment with less cost, a higher chance of pregnancy per embryo transfer, and reduce the negative effects of infertility on couples.

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Abdominal stretching surgery (Abdominoplasty) is performed on people who have sagging in the abdominal area for various reasons. Women and men with sagging after pregnancy or deformities in the abdominal area due to rapid weight loss naturally or after obesity surgery are the appropriate patient group for this procedure.

With the tummy tuck operation, the appearance of sagging skin is eliminated, excess fat in the area is removed, the abdominal area is flattened and a more fit and aesthetic appearance is achieved.

Abdominal stretching surgeries can take between 2-5 hours depending on the surgical technique and the size of the area where the procedure will be performed. The patient is discharged after staying in the hospital for an average of 2-3 days.

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Breast Lift (Recovery) surgery is one of the aesthetic surgeries performed to eliminate deformation in the breasts.
Breast tissue may sag and deform over time due to reasons such as pregnancy, breastfeeding and losing too much weight. However, it is possible to have more upright and aesthetically pleasing breasts with breast lift surgery.

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AREAS OF INTEREST
Pregnancy Follow-up and Childbirth Risky Pregnancy Follow-up
 Gynecological Surgeries
 Genital Aesthetics
 Treatment of Vaginal Infections
 Childbirth in water


EDUCATION
Medical Training : İstanbul University
Speialist Training : Gülhane Military Medical Academy

EXPERIENCE
2006 - Currently :Private Hüma Obstetrician and Gynecology Hospital

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AREAS OF INTEREST
Pregnancy Follow-up and Birth
Genital Aesthetics
 Risky Pregnancy Follow-up
 Infertility
  Treatment of Vaginal Infections
  Gynecological Surgeries
  Family planning
  Childbirth in water
  Menopause Treatments
  Female Sexual Dysfunctions
  Urinary Incontinence OperationsEDUCATION
Medical Training : Istanbul University, Cerrahpasa Medical Faculty
Speialist Training : Istanbul University, Cerrahpasa Medical Faculty

EXPERIENCE
2016 - Currently : Private Hüma Obstetrician and Gynecology Hospital
2015 - 2016 : Private Melikgazi Hospital
2006 - 2012 :  Private Hüma Obstetrician and Gynecology Hospital

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AREAS OF INTEREST

  • Perinatology (Risky Pregnancy)

  • Detailed Ultrasound

  • 11-14 weeks pregnancy examinations

  • Prenatal diagnosis, Genetic counseling

  • Amniocentesis, Cordocentesis, Chorionic villus biopsy

  • Some therapeutic fetal interventions

  • Gynecological Diseases and Operations

  • Laparoscopy

  • Hysteroscopy

 

  EXPERIENCE

  •2022 - continued: Private Hüma Maternity and Maternity Hospital

  •2000-2022: Professor - Erciyes University Faculty of Medicine, Department of Obstetrics and Gynecology

  •1994-2000: Associate Professor - Erciyes University Faculty of Medicine, Department of Obstetrics and Gynecology

  •1991-1994: Assistant Professor - Erciyes University Faculty of Medicine, Department of Obstetrics and Gynecology

  •1988-1991: GATA Haydarpaşa Training Hospital

 

  EDUCATION

  • Minor Specialization: Erciyes University Faculty of Medicine/Perinotology

  • Specialization: Erciyes University Faculty of Medicine

  • Medical Education: Hacettepe University Faculty of Medicine, Erciyes University Faculty of Medicine

 

  CERTIFICATE

  • Perinatology, Prenatal Diagnosis

  • Istanbul University Capa Faculty of Medicine, Department of Obstetrics and Gynecology, Department of Pernatology.

  • King's College Hospital, Harris Birthright Research Center For Fetal Medicine, London/England

  • Yale University School of Medicine ,Maternal-Fetal Medicine, Faculty of Medicine, New Hawen, Connecticut /United States

  • Laparoscopy, Hysteroscopy

  • Royal Free Hospital, London/ England

 

  PUBLICATIONS (click)

  CONGRESS Session Chairs and speeches (click)

 

  MEMBERSHIPS

  • Turkish Maternal Fetal Medicine and Perinatology Association

  • Turkish Gynecology Association

  • Turkish Medical Association

CERTIFICATE

 • Perinatology, Prenatal Diagnosis
 • Istanbul University Capa Faculty of Medicine, Department of Obstetrics and Gynecology, Department of Pernatology.
 • King's College Hospital, Harris Birthright Research Center For Fetal Medicine, London/England
 • Yale University School of Medicine ,Maternal-Fetal Medicine, Faculty of Medicine, New Hawen, Connecticut /United States
 • Laparoscopy, Hysteroscopy
 • Royal Free Hospital, London/ England





 MEMBERSHIPS

 • Turkish Maternal Fetal Medicine and Perinatology Association
 • Turkish Gynecology Association
 • Turkish Medical Association

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EXPERIENCE

*2003-2009 Ankara Education Research Hospital

*2009-2010 Siirt Birth Home

*2010 Siirt Maternity Hospital

*2011-2013 Yozgat Healing Hospital

* 2013-2017 Bozok University

*2017-2022 Private Medical Palace Hospital

*2022 Private Huma Hospital – Still Continued

EDUCATION

Expertise: Gazi University Faculty Of Medicine

Expertise: Ankara Education Research Hospital


Gynecology and Obstetrics

AREAS OF INTEREST

Pregnancy Tracking

Risky Pregnancy Follow-up

Ovarian Cysts and Myoma Treatments

Menopause Treatments

Infertility Treatment and Vaccination

Birth Control and Family Planning

Treatment of Vaginal Infections

Abduction Operations Operations

Birth in water

Genital Aesthetics

Irregular Vaginal Bleeding

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Dietician Ferruha Hüsrevoğlu Completed her medical education in 2009. She has been serving her patients in the nutrition and dietetics department since 2010.

INTEREST AREAS
Healthy nutrition program
Healthy weight loss
Healthy weight gain
Nutrition during pregnancy
Nutrition during adolescence
Nutrition in diabetes
Nutrition after sleeve gastrectomy and gastric botox

EDUCATION
2009 Başkent University Faculty of Health Sciences

WORK EXPERIENCE
2009 Private Hayat Hospital
2010-Present Private Hüma Gynecology and Obstetrics Hospital

MEMBERSHIPS
Turkish Dietitians Association

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EDUCATION

  • Medical Education: Erciyes University Faculty of Medicine
  • Specialization: Erciyes University Faculty of Medicine, Pediatric Surgery
  • Associate Professorship: Harran University Faculty of Medicine

WORK EXPERIENCE

  • Niğde State Hospital: 1998-2006
  • Erciyes University Faculty of Medicine: 2006-2011
  • Balıklıgöl State Hospital (Şanlıurfa): 2011-2013
  • Harran University Faculty of Medicine: 2013-2022
  • SBÜ Kayseri City Hospital: 2022-2024
  • Private Hüma Hospital: 2024-Present

AREAS OF INTEREST

General Pediatric Surgery

  • Congenital diaphragmatic hernias
  • Intestinal atresias
  • Gastroesophageal reflux
  • Esophageal pathologies (esophageal atresia, achalasia)
  • Pyloric stenosis
  • Abdominal wall defects (omphalocele, gastroschisis)
  • Inguinal pathologies (hydrocele, inguinal hernia)
  • Intussusception
  • Intra-abdominal masses (Wilms tumor, neuroblastoma, hepatoblastoma)
  • Sacrococcygeal teratomas
  • Ovarian pathologies
  • Biliary atresias
  • Biliary tract diseases

Pediatric Urology

  • Congenital uropathies
  • Ureteropelvic junction obstruction
  • Ureterovesical junction obstruction
  • Vesicoureteral reflux
  • Undescended testis
  • Bladder exstrophy and epispadias complex
  • Hypospadias
  • Urinary incontinence
  • Nocturnal enuresis

MEMBERSHIPS

  • TTB - Turkish Medical Association
  • PEDURO - Pediatric Urology Association
  • TÇCD - Turkish Pediatric Surgery Association
  • Kayseri Medical Chamber

CERTIFICATIONS

Abnormalities Diagnosed During Pregnancy:

(Including issues related to the respiratory system, kidneys, bladder, diaphragmatic hernia, abdominal wall anomalies, esophageal/bowel atresias, and some congenital tumors)

Congenital Anomalies Detected in the Neonatal Period (0-28 days):

  • Respiratory system and lung anomalies
  • Esophageal anomalies
  • Stomach and intestinal system anomalies
  • Liver and biliary tract anomalies
  • Kidney, urinary tract, and bladder anomalies
  • Abdominal wall formation anomalies
  • Congenital tumors

Issues Detected During Infancy (2-24 months):

  • Congenital anomalies (respiratory system, gastrointestinal system, reproductive and urinary tracts)
  • Intestinal bleeding
  • Intussusception (telescoping of the intestines)
  • Meckel's diverticulum
  • Pyloric stenosis (narrowing of the stomach outlet)
  • Bile duct obstructions

Common Issues Encountered at All Ages:

Surgical Problems:

  • Inguinal hernia
  • Hydrocele
  • Undescended testis (cryptorchidism)
  • Umbilical hernia
  • Appendicitis
  • Intestinal obstructions
  • Foreign objects in the respiratory or gastrointestinal system
  • Constipation, anal fissures
  • Recurrent urinary tract infections
  • Issues with fecal and urinary incontinence (encopresis, enuresis)

ISSUES RELATED TO THE ESOPHAGUS

  • Stomach reflux (gastroesophageal reflux)
  • Esophageal burns and strictures (corrosive esophagitis)
  • Swallowing difficulties (esophageal web, achalasia)

ISSUES RELATED TO THE GASTROINTESTINAL SYSTEM

  • Stomach outlet obstructions (infantile hypertrophic pyloric stenosis)
  • Small and large intestine obstructions (intestinal obstruction)
  • Hirschsprung disease (congenital aganglionic megacolon)
  • Absence of the anus (anal atresia)

ISSUES RELATED TO THE LIVER AND BILIARY TRACTS

  • Liver cysts (simple cysts, hydatid cysts)
  • Congenital bile duct abnormalities (choledochal cyst)
  • Pancreatic abnormalities
  • Gallstones (cholelithiasis)

ISSUES RELATED TO THE KIDNEYS AND URINARY TRACTS

  • Kidney outlet obstruction (ureteropelvic junction obstruction, UPJ)
  • Kidney reflux (vesicoureteral reflux, VUR)
  • Narrowing of the urinary tract (ureterovesical junction obstruction, posterior urethral valve)
  • Stone disease (urolithiasis, nephrolithiasis)
  • Improper placement of the urinary opening (hypospadias, epispadias)
  • Absence of the bladder front wall (bladder exstrophy)
  • Disorders of sexual differentiation (ambiguous genitalia, intersex conditions)

ISSUES SPECIFIC TO GIRLS

  • Ovarian cysts and ovarian torsion
  • Absence or obstruction of the uterus or vagina
  • Closed hymen (imperforate hymen)
  • Adhesions in external genitalia (labial synechiae, labial fusion)

CHILDHOOD CANCERS

  • Kidney and adrenal gland tumors (Wilms tumor, neuroblastoma)
  • Liver tumors (hepatoblastoma, hepatocellular carcinoma)
  • Lymph node tumors (leukemia and lymphomas)
  • Muscle tissue tumors (rhabdomyosarcoma), soft tissue tumors
  • Endocrine gland tumors (thyroid, pancreas, adrenal gland surgical conditions)
  • Tumors of the testes (in boys) and ovaries (in girls)
  • Issues related to the blood vessels and lymphatic system (hemangiomas and lymphangiomas)

OTHER ISSUES

  • Neck curvature (torticollis)
  • Ingestion of foreign objects (foreign bodies in the esophagus, stomach, or intestines)
  • Aspiration of foreign objects into the airway (foreign bodies in the trachea or bronchi)
  • Chest wall depression (funnel chest, pectus excavatum)
  • Chest wall protrusion (pigeon chest, pectus carinatum)
  • Falls
  • Accidents
  • Blunt or penetrating trauma

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“Ovarian hyperstimulation syndrome”, also known as Ovarian Hyperstimulation Syndrome (OHSS), in the most basic way; It can be explained as a reaction to the hormones given to women for the development of the ovaries. During IVF treatment, women are given hormone drugs to stimulate and support egg development. When these hormone drugs stimulate the ovaries more than necessary, the syndrome of overstimulation of the ovaries occurs.


How Ovaries Stimulation Happens?

Ovarian hyperstimulation syndrome (OHSS) is an undesirable consequence of IVF treatment. Although the aim of IVF treatment is to develop a large number of eggs, OHSS may occur if more than a certain number of eggs develop.

Women with polycystic ovary syndrome are much more likely to have ovarian overstimulation syndrome. Excessive response to the drugs given to stimulate the ovaries prepares the ground for encountering this syndrome. During the stimulation of the ovaries, there is a fine line between stimulating the desired number of eggs and over-stimulating the ovaries. It is not always possible to determine this point clearly. When there is overstimulation, reducing the dose of ovarian stimulating drugs and not giving the drug for a day or more, if needed, can prevent the excessive rise of estrogen.


Symptoms of ovarian hyperstimulation syndrome can be mild, moderate or severe. These symptoms are;

-Increased ovarian size

- Abdominal pain, bloating, shortness of breath, decreased urination

-Fluid accumulation in the abdominal cavity

-Coagulation disorders

It can be seen as fluid collection in the chest cavity. It is extremely important to follow these situations closely and to get medical support when necessary.


How is Ovarian Overstimulation Syndrome Treated?

OHSS treatment is carried out to relieve the expectant mother, reduce ovarian activity and prevent complications. However, OHSS can be performed in two different ways as drug and surgical treatment. In mild cases, no additional treatment is required other than outpatient follow-up and severe physical activity restriction, and the patient can usually recover in 10-14 days. Moderate and severe cases may require hospitalization and treatment. In most cases, women who have had OHSS can continue IVF. It is still possible to become pregnant despite OHSS, but these symptoms may worsen if pregnancy occurs. In this case, the patient is followed closely under the supervision of a doctor.


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IVF treatment, which is preferred by couples who cannot conceive naturally and cannot have children, is a source of hope for couples who cannot have children due to the development of medicine and technology. IVF treatment is the fertilization of male and female reproductive cells outside the body under laboratory conditions. Currently, couples have a 95 percent chance of success with IVF treatments. IVF treatment is one of the most successful methods in the treatment of infertility, the cause of which is not clear, or which cannot be conceived in the most natural ways. If couples do not succeed in their first attempts at IVF treatments, they should not despair and stress immediately. Because there are no restrictions on IVF treatment.

How many times can IVF treatment be tried?

 

A study conducted on couples undergoing IVF treatment shows that the rate of achieving pregnancy in couples after the first three trials is 95 percent. In addition, no number can be given about the number of treatments in the remaining group. The experts are also 4. or 5. there is an opinion that the chances of IVF success in trials are slightly lower than in the first three trials. The success rate of IVF treatment does not depend on many attempts. Multiple factors, such as the age of the couples, obtaining a quality embryo, affect the success rate of IVF treatment at a critical point.


Is Success Achieved in the First Attempt in IVF?

The chances of pregnancy during the one-month treatment period with the insemination method or ovulation treatments are about 20% or slightly more than the chances of a healthy couple becoming pregnant in a month. These treatments can be tried 3 or 4 times until pregnancy is achieved, but most of the pregnancies are obtained in the first months of treatment. Continuing treatment for more than 4 years will not increase the chances of pregnancy, so you can switch to IVF treatment.


Currently, thanks to newly developed methods and applications, the success rate of in vitro fertilization treatment is gradually increasing, if success is not achieved at the first attempt, repeated attempts can be made. The chance of becoming pregnant in a month with IVF treatments varies depending on age, but on average it is up to 50-60%. Pregnancy rates can increase by more than 90% after 4 applications when more than one treatment is performed in a row. For this reason, the chances of becoming pregnant increase with the number of attempts in couples who do not have a specific problem.


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In some cases, it is not enough if only the reproductive system is healthy for pregnancy to occur. Along with the reproductive system, it is extremely important for the pregnancy process that many factors work in harmony with each other. Depending on the factors that affect the process, pregnancy may not occur in people. This condition can also be observed if the person has already become pregnant or had a healthy birth.
Infertility, which occurs as a result of a couple having regular sexual intercourse for 12 months and not being able to get pregnant even though they are not using a method of protection, can be seen in two different ways. Never before pregnancy occurs when primary infertility; a live birth or not, regardless of if at least one pregnancy occurred, secondary (secondary) infertility is defined as.
You can continue reading our article about what is secondary infertility, what are its causes, important risk factors and treatment topics.

Causes of Secondary Infertility


Secondary infertility can occur due to both of the couples. The causes of secondary male infertility; the presence of varicose veins in sperm vessels, known as varicocele, infections, traumas and testicular tumors can be listed in the form of. The causes of secondary infertility in women are causes such as differences in ovulation patterns, damage or blockage of the tubes, deterioration of the structure of the uterus, and cervical and cervical cancer, especially as age progresses.
Autoimmune diseases and sexually transmitted diseases are also among the causes dec lead to secondary infertility.
In order to determine which of the many factors considered to cause the development of secondary infertility in people and to make appropriate planning, the couple should consult a specialist physician.

Risk Factors for Secondary Infertility



One of the most curious points about secondary infertility is the risk factors of secondary infertility. Many risk factors can cause the development of secondary infertility in people. These factors;
• Progression of age
• Different disorders such as polycystic ovary syndrome
* Excess weight
• Previous miscarriages
* Stress
* Alcohol, smoking and substance use
It can be sorted as follows. Along with all this, various factors that may differ from person to person can also lead to the development of secondary infertility in people.

Treatment of Secondary Infertility



The causes of secondary infertility, which are an obstacle to a person's conception, can be studied in an extremely wide range. For this reason, first of all, the points that prevent a person from becoming pregnant should be determined by taking into account different factors and an appropriate treatment plan should be developed accordingly. As a result of the evaluations made by taking the patient's history, vaccination and IVF treatments may be recommended to support conception. In order to determine the condition, specific infertility tests can be administered to people after a physical and pelvic examination. The ovulation test and other hormone tests are some of them.
As Huma IVF center, we continue to be with you in this process with our expert staff. For all the questions you have in mind, you can contact us by checking out our experts on our website.

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IVF treatment; It is the method that offers the highest chance of pregnancy for couples who want to have a baby but cannot conceive naturally. In vitro fertilization method can be applied as a result of unprotected intercourse for more than 1 year, when pregnancy does not occur. Although it is a successful method, it may not always be possible to achieve 100% success in IVF treatments. There are many factors that determine the probability of successful IVF treatment. 


What Factors Depends on Success in IVF Treatment?

In IVF treatment, it is aimed to catch pregnancy in the first time, but pregnancy is not possible for every woman at once. Factors affecting the success of IVF treatment include the age of the expectant mother, weight status, problems in the uterus, hydrosalpinx in the tubes, immune system problems, smoking degree, alcohol use rate, and decreased ovarian reserve. With this; Various male-related conditions such as sperm immobility, severe deformities, and absence of sperm in the semen also affect the success rate of IVF treatment. General statistical data can give you information about the success rate in IVF treatment, but it should not be forgotten that every couple is very special and unique. In IVF treatment, your doctor can better determine your individual chances, taking into account your personalized factors. 


What are the Risks of IVF Treatment?





As with any treatment, there are some risks in IVF treatment. However, some of these risks, which are likely to be encountered in IVF treatment, are predictable and can be intervened early, although these risks are very rare. We can list these risks as follows: Mild bruising, swelling and pain may occur in the areas where the drugs were injected. Overstimulation of the eggs can result in weight gain, nausea, vomiting and bloating. There may be a risk of ectopic pregnancy. Bleeding may occur during egg collection.


What Should Be Done After Unsuccessful IVF?



 Failure of one or more IVF attempts can be extremely challenging, disappointing couples. This situation is extremely natural. One of the most important reasons for a failed IVF treatment is poor embryo quality. Defective and damaged embryos cannot be attached to the uterus after they are transferred to the uterus. However, in some cases, pregnancy may not be achieved despite transferring good quality embryos. Your doctor will evaluate the reasons for the failure of your IVF process in detail to determine what the problem is. These points will be taken into account in future attempts after the problem is determined. Taking a break for at least a month after a failed IVF attempt will also be very beneficial for the process. As developments in the field of medicine increase, it becomes easier to detect and eliminate negative situations. It is important that couples who fail their first IVF attempt should not despair. When conditions are improved, the chances of pregnancy will be higher in subsequent attempts.

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There are 2 treatment methods most commonly preferred by couples who want to have a baby but do not have a baby for various reasons. One of them is in vitro fertilization treatment and the other is insemination method. In our article, we will try to answer the most frequently asked questions about the vaccination method, what is insemination and how it is done.


What is insemination? 


If couples cannot get a pregnancy result after one year after unprotected sexual intercourse, infertility is diagnosed. Infertility can have many causes, depending on the woman and the man. Thanks to science and developing technology, there are now many treatment methods for infertility. One of these methods is the vaccination method. In its simplest form, the method of vaccination is to prepare the sperm in the laboratory and inoculate the woman's uterus at the time of ovulation to ensure fertilization. In order for the vaccination method to be performed, some tests must be done to make sure that there is no problem in the uterus of the expectant mother. In addition, at least one of the tubes of the expectant mother must be in working condition. The purpose of the vaccination method is to select the motile, normal sperm with a higher probability of fertilization and send them to the uterus of the expectant mother. Thus, it will be more likely to be fertilized with eggs and selected sperm supported by drugs or pills. 


How is insemination done?


Before the insemination method, the development of the egg is supported with pills or low-dose injections given to the expectant mother. During this process, the egg is tracked. When the eggs mature and reach certain sizes, a cracking needle is given and the eggs are cracked. Just at this time of cracking, the sperm prepared in the laboratory are transferred to the uterus. Thus, the most suitable time of ovulation is provided for the woman and the best sperm are transferred to the uterus at the right time. insemination is a natural method. Only sperms that will increase the probability of fertilization are carefully selected. From the sperms taken from the father-to-be, those that are of good quality, motile and washed in a certain number, that is, processed. As Hüma IVF Center team, we tried to give information about what is insemination and how it is done in our article. We hope it was useful. You can contact us via our website to get more detailed information about IVF treatment or to ask your questions.

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As couples who want to become parents cannot become parents with natural methods, couples resort to some treatments. In vitro fertilization is the first treatment method. And IVF treatment is a very advanced and effective treatment method. Some applications in IVF treatment are important for the positive outcome of the treatment. Embryo glue application, which is one of the important application methods, is a very successful application. Embryo glue is one of the applications without any known risk. As a result of the studies, it was concluded that it did not increase the risk of miscarriage or pregnancy complications. Now we will provide you with detailed information about embryo glue. We wish you pleasant reading.

What is Embryo Adhesive?



Embryo glue, a method used in IVF treatments, is a kind of liquid embryo culture medium enriched with a substance called hyaluronan, in which embryos are left before transfer to the uterus of the expectant mother.

Hyaluronan is a natural carbohydrate found in all tissues in the body. The embryo needs an environment rich in carbohydrates, amino acids and protein in order to develop healthily inside. In addition, embryo glue is also called embryo glue because it reduces the ability of the embryo to move in the uterus.

How and Who Is Embryo Adhesive Used?



Embryo adhesive application is done as follows:

After the embryos are developed in the laboratory for 3-5 days, the most suitable one for embryo transfer is selected.

· The most suitable embryos selected for transfer are taken into the embryo glue.

· Embryos are kept in this environment for about 30 minutes.

· After standing, the embryos are taken from the culture dish and drawn into the catheter (a thin tube).

· The catheter is then passed through the cervix under ultrasound guidance and the embryos are transferred to the uterus.

In expectant mothers who have repeated in vitro fertilization failure using the embryo glue method,

It is used in couples who want to have children over the age of 35, when the quality of the embryo depending on the egg or sperm is not very good.

Is the Success Rate High in Embryo Bonding?



Embryo adhesive is one of the most frequently used applications for the last 10 years in order to increase the chance of success in IVF treatment. Experts were unsure about the effectiveness of embryo glue at first. However, in recent years, the effectiveness of embryo glue has been observed as a result of scientific research. Today, embryo glue is applied by various IVF centers. Hüma IVF Center is one of these centers.

The high concentration of hyaluronan concentrates the embryo glue similar to the tissue of the fluids in the womb, so that better mixing of these fluids minimizes the mobility of the embryo. In addition, hyaluronan acts as a bridge between the embryo and the inner wall of the uterus by binding to the inner wall of the uterus and the molecules on the surface of the embryo. In this way, it helps the embryo to attach to the uterus.

We aimed to give you information on this subject by considering the embryo glue method. We talked about how this method is applied and its success rate.

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WHAT IS INTRALPID SERUM TREATMENT? WHO IS APPLIED?


Intralipid serum therapy emerges as a form of treatment applied to women who want to become pregnant but cannot achieve this goal as a result of recurrent IVF failures. It is extremely important that the immune system is strong during IVF treatment. Intralipid serum therapy is a method used at this point to strengthen the immune system.

Intralipid serum treatment is started to be applied to women who want to become pregnant before starting IVF treatment. What are the details of intralipid treatment? Who is intralipid serum therapy applied to? How is intralipid serum therapy applied? Now we will be giving answers to all these questions for you below.


What is Intralipid Therapy?



Intralipid serum therapy is a treatment for women who want to become mothers. Intralipid serum is a treatment method that starts on the day of transfer and continues throughout the process in IVF treatment. Intralipid serum contains many important proteins and molecules for the immune system. Thanks to this serum, it is aimed to keep the immune system of the expectant mother strong during pregnancy by supporting the immune system.


To Whom Is Intralipid Serum Treatment Applied?



Intralipid serum therapy is a treatment for women who want to become mothers, but only for those who have experienced miscarriage problems or who have experienced IVF failures. The purpose of this treatment is to ensure that the immunity of the expectant mother remains strong throughout the pregnancy process.

As a result of the information obtained, it has been proven that intralipid serum therapy does not have any side effects. However, some women may be allergic to the substances in the intralipid serum. At this point, good research should be done before starting the treatment and if there is no allergic condition, treatment should be applied.


How is Intralipid Serum Treatment Applied?



Parents who want to have a child can resort to many ways for pregnancy to occur. In vitro fertilization, which has been very popular recently, has been determined as the most successful assisted reproductive method. If there are recurrent failures as a result of IVF treatment, this problem can be eliminated with intralipid serum treatment. Intralipid serum therapy is an extremely effective and successful form of treatment.

Intralipid serum treatment is administered to the expectant mother by intravenous route, with a preparation containing emulsified oil, prepared with a special concentration, which takes approximately 45 minutes. In other words, the patient's immune system is supported by giving oily serums intravenously.

In this article, we have given detailed explanations about inralipid serum therapy and that parents can receive intralipid serum treatment in cases where pregnancy does not occur due to some reasons. If you want to have more detailed information on this subject, you can visit https://www.humatupbebek.com/.

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IVF treatment, which is one of the methods of treatment that helps reproduction, begins with the collection of eggs from the expectant mother and the removal of sperm cells from the expectant father. The embryo, which appeared after the fertilization was carried out in the laboratory environment, is placed in the womb of the expectant mother. From this point on, pregnancy continues like a pregnancy acquired by natural means.







When should couples who cannot have children turn to IVF treatment?



A woman under the age of 35 who does not have any diseases that can prevent her from becoming pregnant should definitely be examined if she cannot conceive despite having unprotected and regular sexual intercourse for 1 year and seek treatment if deemed necessary. Women who are over the age of 35 or who have previously had any problems affecting conception should only try for 6 months.







How is IVF Performed? What are the Necessary Conditions?



In vitro fertilization can be defined as the process of placing the healthiest embryo in the womb obtained as a result of fertilization of eggs collected from the expectant mother with the sperm of the expectant father in the laboratory environment. Before starting IVF treatment, the reproductive abilities of both a man and a woman are evaluated. Then hormone therapy is started to allow the expectant mother's eggs to enter the maturation process. Then, a cracking needle is made and the eggs are released from the follicles. During the egg collection process, the ripening eggs of the expectant mother are collected with the help of transvaginal ultrasound. At this time, sperm cells are taken from the expectant father. 









Fertilization is achieved by means of reproductive cells that are brought together in a laboratory environment dec The healthiest of the embryos that occur, or in other words, the best IVF, is transferred to the expectant mother's uterus accompanied by ultrasound. After about half an hour after this procedure, the couple is sent home. In some cases, more than one embryo needs to be transferred to the mother's womb.

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Beta HCG hormone is a hormone known as the pregnancy hormone among the people. It is used in pregnancy tests to determine whether the person is pregnant or not. Experts express the test to measure the beta HCG hormone in different ways. You may have heard of Beta HCG blood test, quantitative blood pregnancy test, quantitative HCG test, and quantitative serial Beta HCG test. In this article, we have brought together all the curious about Beta HCG. What should be the Beta HCG value? What does low or high Beta HCG mean? Read on for the answers to all these questions.


What is Beta HCG?

There are 2 types of HCG Hormone, Beta and Alpha. During the pregnancy test, the Beta hormone is examined and is called Beta HCG. Beta HCG hormone is secreted by the placenta with the occurrence of fertilization. A blood test is performed between 10 days and 14 days after fertilization, and a high value can be observed in Beta HCG hormone as a result of the blood test. After a day or two, a urine test is done and more precise data for pregnancy can be obtained. High beta hcg hormone does not only mean a sign of pregnancy. Depending on some diseases encountered in people, its level in the body may increase, this varies from person to person. For this reason, when a high level of Beta HCG hormone is detected, different tests are performed immediately and it is ensured whether pregnancy has occurred or not.


What Should Beta HCG Value Be?


In a healthy non-pregnant woman, Beta HCG hormone varies in the range of 0-10 mlU/ml. In fact, it is usually seen at values ​​around 0 and 0. With pregnancy, these values ​​increase. In other words, we can understand whether pregnancy exists or not from the height of this hormone.


What Does Low and High Beta HCG Mean?


Beta HCG elevation first suggests that the person is pregnant. Because pregnancy increases the Beta HCG hormone. This hormone may give false information in some periods. Especially if the person has a different ailment, for example; In cases such as gastritis, some types of pancreatic cancer, some stomach cancers, ovarian cancer, liver tumor, multiple pregnancy, high levels of this hormone can be detected. For this reason, it is not possible to understand that you are pregnant with this test alone. Afterwards, you must have different tests. In addition to these, it is possible to say that the foods eaten also affect this hormone. Foods high in progesterone such as dill, avocado, spinach, tomatoes and walnuts increase the Beta HCG value.

Beta HCG is usually 0 and close to 0 in normal, ie non-pregnant individuals. In individuals who are pregnant, the low level of this hormone may be due to many reasons. These; ectopic pregnancy, deviation in the calculation of the week of pregnancy, sudden miscarriages.


In this article, we have discussed the Beta HCG hormone in detail. We have made explanations for you by giving place to all the questions that are curious. For more, you can visit our Hüma IVF page.

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Serum Intralipid Therapy is a treatment used specifically to strengthen the immune system. The immune system plays a big role in the repeated IVF failures and recurrent miscarriages seen in some women. For this purpose, intralipid serum therapy is also used. This is a type of treatment that is started prior to IVF treatment and is applied once a week or every two weeks until the baby's heartbeat is heard, if deemed necessary after pregnancy is achieved. Now let's take a closer look at intralipid serum treatment together ...

What is Intralipid Serum Therapy?

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Intralipid serum therapy is a form of treatment that starts on the day of the transfer and continues throughout the process. Intralipid whey contains fat molecules and soy protein, which strengthens the immune system. The immune system is extremely important for a healthy pregnancy and its continuation. Because half of the child belongs to the father, the mother's body does not reject it. In vitro fertilization failure also occurs in case of rejection, but intralipid therapy can prevent this failure.

For whom and how is intralipid serum treatment applied?

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Intralipid Serum Therapy is an immune-boosting treatment that is commonly used in women with recurrent miscarriage problems and recurrent IVF failures. As a result of studies, it was found that treatment with intralipid serum does not have side effects. Only women can be allergic to some substances in the serum of intralipid, in which case this should be determined in advance. These substances are a number of special ingredients such as glycerin, egg phospholipids. It is preliminarily checked whether the patient is allergic to these substances. If the patient has an allergy, treatment is not applied.

Intralipid whey treatment is carried out with a preparation containing emulsified oil prepared with a special concentration, which takes approximately 45 minutes. Fatty sera are administered to the patient intravenously.

In this article: what is serum intralipid therapy, who is this treatment for, how is intralipid therapy used? We have answered all these questions for you. If you want to get more detailed information about this, we recommend that you visit the website of the HUMA center.

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What is infertility, what are its symptoms, what kind of treatment method is applied?



Infertility, as it is called in the medical literature, is one of the most important health problems affecting millions of people around the world. In addition to being a health problem that can be seen in women and men, today the number of couples who cannot have children is quite high. According to researches, 10-15% of couples who have unprotected sexual intercourse for a year cannot have a child.

In our article, about infertility, one of the most important health problems in the world; We will try to give short answers about what is infertility, what are the symptoms of infertility and how to apply the treatment method.




What is infertility?


According to the definition of the World Health Organization, infertility; “Failure to conceive within one year of a sexually active couple who had unprotected intercourse without using contraception.” is the status. In other words, in order to be able to talk about infertility exactly, couples must have unprotected intercourse for one year and be unable to conceive. Infertility is one of the important health problems affecting 25% of the world population. In the researches, it can be seen depending on the woman or the man.

What are the symptoms of infertility?

The most important sign of infertility for both men and women is the inability to get pregnant despite having unprotected sexual intercourse for one year. However, some symptoms seen in men and women can be seen as a sign of infertility and an examination may be required accordingly.


 infertility in women;


- Imbalances in the menstrual cycle can be considered as a symptom. If you have periods longer than 35 days or shorter than 21 days, you should definitely see a specialist.

- If you are in your 30s and younger, it is expected to get pregnant within 1 year.

- If you are in your 35s and 40s, pregnancy is expected within 6 months. If pregnancy does not occur within 6 months, it is useful to see a doctor.


Infertility in men;


- Sexual dysfunctions are considered a sign of infertility. Example; impotence, ejaculation, such as strain.

- Pain, swelling or a lump in the testicle area during sexual intercourse may also be a sign of infertility.

- Infertility in men can often be caused by hormonal disorders.

Although all these symptoms are not exactly the cause of infertility, they are among the factors affecting it and may be symptoms of infertility.



What kind of treatment method is applied in infertility?







There can be many different reasons for the occurrence of infertility. Therefore, first of all, the causes of infertility are investigated. Different treatment methods are tried according to the detected cause. Some of the treatment methods applied are as follows;

- IVF Treatment

- Vaccination

- Microinjection

In vitro fertilization is one of the most well-known and most preferred and effective treatment methods among other treatment methods.

As Hüma IVF Center team, we tried to give information about what is infertility, what are its symptoms and what kind of treatment method is applied in our article. We hope it was useful. You can contact us via our website to get more detailed information about infertility or to ask your questions.

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Adenomyosis is a female disease that occurs in women, especially as age increases. Women with adenomyosis experience extremely painful, painful and excessive bleeding menstrual periods. This heavy menstrual period also affects the daily life of women with adenomyosis. In addition, it causes anemia. If you are experiencing these problems and want to know more about Adenomyosis, you can continue reading our article.

What is Adenomyosis?



The uterus contains an inner lining of the uterus called the endometrium. The task of this inner membrane is to limit the inner surface of the uterus. The inner membrane inside the uterus is renewed every month with the menstrual period and in some women it moves towards the uterine muscle layer. Adenomyosis occurs as a result of thickening of the inner membrane in the uterine muscle layer.

There are two types of adenomyosis: benign and malignant. It is a benign type that is usually seen in women, but some women may also have a malignant type that requires surgery and poses a risk.

Women with adenomyosis have difficult days during their menstrual periods. During this period, they may have to cope with excessive pain and excessive bleeding. Again, they may feel uncomfortable bloating before the menstrual period and may experience pain and pain during sexual intercourse.

What are the Causes of Adenomyosis?



Although the causes of adenomyosis disease in women are not known clearly, it is known that hormones such as estrogen, prolactin, and progesterone trigger this ailment. Apart from this, external interventions in cesarean deliveries, surgical cuts or inflammation of the inner lining of the uterus during birth trigger the cells that regulate the uterus to leave their borders and cause adenomyosis. Development-related adenomyosis can also be seen. During the developmental process, the endometrial accumulation formed between the muscles during the first formation of the fetus in the uterus may cause adenomyosis.

What is the Relationship Between Adenomyosis and Infertility?



The age at which adenomyosis is most common is people between the ages of 40 and 50. Adenomyosis is a female disease related to the uterus. For this reason, we can say that adenomyosis is directly related to infertility and pregnancy. Adenomyosis is a disease whose incidence increases with increasing age, so infertility and adenomyosis can be seen together when pregnancy is considered in older women. Expectant mothers who encounter this situation can achieve their dreams of having a child by trying the in vitro fertilization method after receiving adenomyosis treatment.

What is Adenomyosis Treatment?



Experts have done many studies to treat adenomyosis disease and as a result, they have found various treatment methods. We can talk about hormonal therapy as the first treatment method. With hormonal therapy, it is tried to relieve the pain caused by adenomyosis and to reduce the excess blood. For this, birth control pills, temporary menopause treatments or medicated spiral methods can be used. As a second method, we can consider MRI Focused Ultrasound. In MRI focused ultrasound treatment, high-intensity heat waves are used to destroy the tissue that causes adenomyosis. Another form of treatment is hysterectomy. This form of treatment is the most permanent solution, but because it results in the removal of the uterus, it is applied only to women who do not plan to have children or in severe cases that do not respond to any treatment.

 In this article, we discussed adenomyosis, which is common in older women. What is adenomyosis, what are the causes of this disease, what is the relationship between adenomyosis and infertility, and what are the treatment methods for this disease, based on all these questions, we have made detailed explanations about adenomyosis for you. We wish you a pleasant reading. You can visit our website for more.

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Ovarian reserve, known as the ovary, is a term used to determine the fertilization ability of the ovary to provide egg cells and to determine the probability of a successful pregnancy. With the advancing age of the expectant mother, the number of egg cells obtained from the follicles for pregnancy decreases. decreased ovarian reserve (AMH); It is a condition in which the ovaries begin to lose their normal production capabilities, reducing fertility. Decreased ovarian reserve reduces women's chances of conceiving spontaneously or with treatment. However, it is aimed to minimize the effects of this situation with various methods. The main causes of decreased ovarian reserve can be listed as follows:

· Smoking,

Chronic diseases,

 Coffee consumption

  Age of the expectant mother,

Genetic abnormalities (X chromosome abnormalities)

Various treatments (such as radiation for cancer)

· Having undergone ovarian surgery.

You can continue reading our article for reduced ovarian reserve and all its details.






How to Identify Decreased Ovarian Reserve?



Decreased ovarian reserve is determined by examining the hormone tests to be performed on the 2nd or 3rd day of the menstrual period of the expectant mother. FSH hormone gives information about the status of ovarian reserves. If the FSH value is higher than 10, it indicates decreased ovarian capacity.

The best indication of the capacity of the ovaries is the vaginal ultrasound. Existing and developing egg structures can be easily detected here. If there are less than six egg structures in the total ovaries, decreased ovarian reserve may be in question.

In summary, decreased ovarian reserve; It can be understood by clinical evaluation of the person, vaginal ultrasound, measurement of AMH hormone and FSH hormone in the blood.



Can a Woman with a Decreased Ovarian Reserve Get Pregnant?



Existing studies show that women with reduced ovarian reserve can become pregnant both spontaneously and with IVF treatment. Although it has been shown that high serum FSH levels in women are associated with low pregnancy rates, it is not sufficient to make a decision based on this alone. Egg cells also regulate their size under the influence of genetic factors. The speed of the aging process of the ovaries varies greatly among women, except for the age factor. In addition to the successful results of endocrine tests and imaging methods in the numerical evaluation of ovarian reserve, their values ​​in determining the chance of pregnancy remain at a limited level.

The chance of conceiving of a woman who is determined to have decreased ovarian reserve with ovarian reserve tests and clinical evaluations by specialist physicians can be increased by applying appropriate ovulation treatment protocols. Patients with reduced ovarian reserve can become mothers with different techniques today. In order to determine these methods, it is important to plan and apply special treatment methods suitable for patients by considering various factors.



How Is Decreased Ovarian Reserve Treated?



Currently, there is no treatment for decreased ovarian reserve that prevents or slows down ovarian aging. In addition, lifestyle changes have an extremely important role in preventing premature aging of the ovaries and in order to ensure the healthy continuation of egg quality, that is, to increase egg reserve and quality. These;

· Eating a balanced and healthy diet,

Doing regular exercise,

Quality and adequate sleep,

Avoiding chemicals, high glycemic index and fast food style foods,

Not to use substances such as cigarettes and alcohol,

· Using antioxidant drugs under the control of a physician.

 

 

If you have decreased ovarian reserve and want to have a child according to your required tests and vaginal ultrasound results, it is extremely important to seek in vitro fertilization treatment in the presence of a specialist doctor, without wasting time.

As Hüma IVF Center, we choose the most appropriate treatment method for you, apply it and continue to serve.

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Going to the gynecologist can be a scary idea for many women. Even accepting this idea can be stressful for women because genital examination is thought to hurt and the feeling of shame prevents women from going to the gynecologist unless they have to. However, gynecological examination is not painful. It does not pose an ethical problem either. Just because of some perceptions, women are hesitant to go to the gynecologist. However, many diseases that have given symptoms during genital examination can be pre-diagnosed. The vagina is entered with a speculum, then a smear is taken and this sample is sent to the laboratory. Necessary procedures are applied in cases where further examination is required according to the result.

 

How is Genital Examination Performed?

Genital examination is done by a healthcare professional. The presence of viruses such as HPV can be detected in the gynecological examination. Since detecting the presence of this virus before pregnancy will affect the pregnancy process, genital examination is important for precaution. Examination is essential in the presence of conditions such as vaginal bleeding, pain in the groin, and discharge. The appearance, smell and quality of the discharge are also very important. Genital examination is of great importance as transparent, milky, yellow or brown discharges can each be a sign of different diseases.

 

What are the Points to Consider?

The necessity of vaginal examination in case of menstrual irregularity, determining a contraceptive method, cervical infections, and pregnancy is indisputable. It can be life-saving for women not to be afraid of genital examination and to go to a gynecologist for diagnosis. Genital examination is of great importance in terms of early diagnosis in very serious diseases such as endometrial cancers, ovarian ca, ovarian cysts, and cervical cancer. Regardless of what, when they see a disease symptom in themselves, it is important not to infect other reproductive organs, so they should consult an obstetrician. While taking anamnesis, they should tell their stories clearly and do their best to regain their health.

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Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.


What is blastocyst transfer?



Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.


What are the advantages of blastocyst transfer?



Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;

The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,

Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,

The chance to observe the embryo development more clearly and healthily,

Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,

· Allowing different methods to examine embryo viability.



What is the risk of blastocyst transfer?



The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.


Who is blastocyst transfer suitable for?



Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.

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Recently, it has been revealed that egg quality obtained from patients with low reserve is lower and genetic problems in the embryo are higher. In this direction, it is aimed to create fewer but better quality embryos by obtaining higher quality eggs with less drugs. Mini IVF appears as a simplified in vitro fertilization practice, unlike the known in vitro fertilization practices performed with daily injections and high-dose drug use. Especially in patients with a low number of eggs or in advanced age, the success rates are higher than conventional treatments. What is mini IVF, who is it applied to and what are the drugs used in its treatment? You can continue reading our article for questions and all the details.


What is mini IVF?



Mini IVF is an in vitro fertilization application that enables the development of fewer but higher quality eggs by using lower doses of drugs. Eggs developed with this method are taken and fertilization is performed by applying the microinjection technique. Embryos formed after fertilization are transferred to the patient, assuming that the probability of attachment is higher.

In addition to the advantages such as less drug use, less cost and less time spent with mini IVF treatment, high success rates can be obtained in patients with a low number of eggs and advancing age.



Who is mini IVF applied to?



In cases where pregnancy does not occur naturally;

Those who want to use hormone drugs less,

At risk of developing OHSS (overstimulation of the ovaries),

Concerned about the daily injection process in IVF treatment,

Those who have problems in the fallopian tubes and are younger than 35 years old,

Having low egg reserve that cannot be increased with treatment,

Looking for a more economical solution than conventional treatment,

People who have tried many times in vitro fertilization but have not achieved a result, and

Mini IVF treatment can be applied to women who want to reduce the possibility of multiple pregnancy.

However, a treatment plan should be made by a specialist by listening to the patient's history of the disease, analyzing their expectations and performing health checks in detail.



What are the drugs used in mini IVF treatment?



Mini IVF treatment is a type of in vitro fertilization that uses little or no medication to increase and develop the number of eggs. In standard IVF treatments, hormone injections are made for 8-10 days to reproduce eggs, while these drugs are not used in the Mini IVF method. Oral tablets and very low dose hormone injections are used instead. With Mini IVF, which is a natural in vitro fertilization method, it is ensured that the highest quality eggs are produced by using the least amount of medication.

Mini IVF method is aimed to obtain better quality eggs with the use of low doses of drugs. At this point, it is possible to determine your treatment plan by consulting your doctor. You can visit our website for more information.

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Calcium ionophore therapy is a treatment method applied to ensure a healthy fertilization and to obtain a high pregnancy rate. In order to talk about a healthy fertilization, when the sperm enters the egg, the enzyme in the head part of the egg must be released into the egg and the amount of calcium inside must increase.

If the amount of folfolipase C in the sperm is low, the egg cannot be fertilized because without phospholipase, the calcium rate in the egg does not increase.

Calcium ionophore therapy is an application that increases the amount of calcium in the egg. In the calcium ionophore application, the egg and sperm are first fertilized by micro-injection. After this process, the eggs are kept in a calcium ionophore for a few minutes. The main purpose here is to increase the calcium level that needs to be increased in the egg. In other words, calcium ionophore therapy helps the fertilization of the egg by supporting the reactions that should start in the egg. So, what is calcium ionophore therapy and to whom is it applied? Now we will answer all these questions for you.



What is Calcium Ionophore? To Whom Is It Applied?

It is possible to define calcium ionophore therapy as an application that increases the amount of calcium in the egg. This treatment method is generally applied to the people we will list below. Those people;

Individuals with successive fertilization problems

If very few eggs or sperm are obtained

In cases where no fertilization can be achieved with micro-injection therapy

In patients with “globosperm” of all sperms

Calcium ionophore therapy is applied.



Who Is Fertilized With Calcium Ionophore?

In cases where embryo transfer cannot be performed due to the fertilization step not taking place during IVF treatment, activation of the eggs and fertilization are aimed by using calcium ionophore. Thus, calcium ionophore therapy is applied. With this treatment method, the problem of non-fertilization can be eliminated and treatment can be applied in couples who have non-fertilization problems. This treatment method is also applied to couples who have problems as a result of obtaining a very small amount of egg and sperm. Fertilization is performed with the calcium ionophore treatment method and a high pregnancy rate is obtained.

In this article, we have given the answers to all these questions for you, what is calcium ionophore therapy, to whom this treatment method is applied and in whom fertilization occurs as a result of the treatment.

It may interest you: What is infertility, what are its symptoms, what kind of treatment method is applied?

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The hormone beta HCG is a hormone that is popularly known as a pregnancy hormone dec It is used in pregnancy tests to determine whether a person is pregnant or not. Specialists express the test for measuring the hormone beta HCG in different ways. It is possible to hear it in the form of a beta HCG blood test, a quantitative blood pregnancy test, a quantitative HCG test, and a quantitative serial Beta HCG test. In this article, we have collected all the curiosities about Beta DECG. What should be the beta HCG value? What does it mean if the beta hCG value is low or high? For answers to all these questions, continue reading our article.

 

What is Beta HCG?

 



 

There are 2 types of the Hormone HCG - Beta and Alpha. When conducting a pregnancy test, the Beta hormone is examined and called Beta HCG. The hormone beta HCG is secreted by the placenta with the formation of fertilization. A blood test is performed dec 10 days and 14 days after fertilization, and as a result of the blood test, a high value of the hormone Beta HCG can be observed. After a day or two, a urine test is performed and clearer data for pregnancy can be obtained. The height of the hormone beta hcg means not only a sign of pregnancy. Depending on some diseases that are found in people, their level in the body may also increase, it varies from person to person. For this reason, when an increase in the Beta HCG hormone is detected, different tests are also performed immediately and it is made sure that the pregnancy does not occur.

 

What Should Be the Beta HCG Value?

 



 

In a healthy woman who is not pregnant, the hormone December HCG varies in the range of 0-10 mlU/ml. Even it is usually seen at an approximate value of 0 and 0. With pregnancy, these values increase. That is, we know from the height of this hormone whether pregnancy exists or not.

 

What Does Low And High Beta HCG Mean?

 



 

The height of beta hCG first makes it clear that the person is pregnant. Because pregnancy increases the hormone Beta HCG. This hormone can give false information in some periods. For example, if a person has a different condition, gastritis, some types of pancreatic cancer, some stomach cancers, ovarian cancer, liver tumor, and multiple pregnancy, this hormone can also be elevated in cases such as gastritis. Therefore, it is unlikely that you will understand that you are pregnant only with this test. After that, you must also have different tests. In addition to these, it october possible to say that the nutrients eaten also affect this hormone. Foods high in progesterone, especially dill, avocado, spinach, tomatoes and walnuts, increase the value of Beta HCG.

 

Beta HCG is normal, that is, it is usually close to 0 and 0 in individuals who are not pregnant. In individuals who are pregnant, a low level of this hormone can be due to many reasons. These are ectopic pregnancy, a deviation in the calculation of the week of pregnancy, sudden miscarriages.

 

In this article, we have discussed the Beta HCG hormone in detail. We have made explanations for you by including all the questions that are curious. For more information, you can visit our Human IVF page.

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Insemination treatment is a method of selecting the sperm that is the highest quality of the sperm taken from the expectant father during the ovulation period, that is, during the period when the probability of conception of the expectant mother is the highest, and then putting it into the womb of the expectant mother. A state of fertilization that has been tried many times by natural means, but no successful results have been obtained, thanks to vaccination treatment, sperm and egg dec easily combined and fertilized. So, how will expectant parents understand this situation when Insemination gives a successful result? We will answer this question and give you more detailed information about Insemination treatment. We wish you a pleasant reading in advance.



What is Insemination?


Insemination is a treatment applied by people who want to become parents but have not been able to achieve this condition by natural means. This treatment, which is performed before starting IVF treatment, is aimed at increasing the chances of pregnancy. Insemination takes place exactly as follows;

· Several necessary tests are applied to prospective parents before.

· Male sperm is taken and the best quality sperm is selected by special procedures.

* Spermatozoa are released into the uterus when the woman's eggs are laid. Here this process is known as the vaccination process.

The vaccination method is a method used in cases where the man's sperm count or mobility is low, when there are problems with the excretion of semen during intercourse, when the woman's cervix is narrow. The cause of infertility cannot be explained in any way.





To Whom Is Insemination Therapy Prescribed?


“Who is the Insemination method applied to?"we can explain the question as follows; It is a form of treatment applied to expectant parents who want to have children, but for various reasons some kind of pregnancy condition cannot be created. For the implementation of this treatment, the man or woman must have some problems that he is experiencing. We can list the problems encountered as follows:

· If there is a lack of sperm count and mobility in a man,

· If there is a problem of unexplained infertility (infertility)

· If the woman has ovulation problems and therefore pregnancy could not be done with egg tracking

· It can be applied in couples who want to accelerate the possibility of pregnancy due to social reasons experienced by couples.



What is the Success Rate of Insemination?


With the development of technology in the medical field and the scientific studies conducted, the success rate of Insemination treatment is quite high. And every day these treatments are being enriched with a new way and it is aimed to increase the success rate of Insemination to the highest level.







When Do the Symptoms of Pregnancy Begin With the Success of Insemination?


There is no difference between the occurrence of pregnancy with Insemination and the occurrence of pregnancy by natural means and the appearance of symptoms in terms of the occurrence of pregnancy Dec In other words, expectant mothers are 3rd of pregnancy, as in naturally occurring pregnancies. from the week she begins to experience signs of pregnancy. These symptoms can be considered as complaints such as dizziness, weakness, nausea and vomiting that occur in the morning. Expectant mothers who have these symptoms can find out if they are pregnant by taking a pregnancy test. 12-14 after Insemination to see if pregnancy has occurred. on the day, the Beta HCG hormone is checked in the blood and it is understood whether pregnancy exists or not. If the pregnancy result is positive, you will need to contact your doctor and undergo an examination to keep it under control. After this examination, a clearer result will be obtained by looking at it with ultrasound and it will be determined whether there is a pregnancy or not.

After Insemination, expectant parents should continue their normal lifestyle. They do not need to change anything in their lives with the introduction of Insemination therapy. In this process, they should only take care of regular and balanced nutrition and protect themselves in the best way. We have shared all the details of the vaccination method with you in this article. If you also want to become a parent and are looking for various treatment methods for this, you can check out our page.

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IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.



What is Comprehensive Chromosome Screening (NGS)?


It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.

Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.


What are the Features of the NGS Technique?




Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.


What Genetic Defects Can Be Detected with NGS-Based PGS?



Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.

To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.


Who are the Groups of Patients Who Can Be Administered NGS?




The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;

· In cases of repeated miscarriage,

· in expectant mothers over the age of 38,

· In severe male infertility,

* In cases of infertility, the cause of which is unknown,

· It is applied in cycles of continuous self-recurring treatment failures.

The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.


What are the Advantages of Preimplantastone Genetic Screening with NGS?




NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.


Does NGS Damage the Embryo?




IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.


Does Pregnancy Always Occur With a Smoothly Detected Embryo?




After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;

· Women's age

· The amount of ovarian reserve of the woman

* Sperm quality

· Embryo quality

· Ensuring a proper intrauterine environment

· The presence of hydrosalpinx

· Conditions encountered during embryo transfer

it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.

Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.

In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.


How Many Days Do NGS Results Come Out?



The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.

What are the NGS Test Prices?

The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.

In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.

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How to Improve Egg Productivity & Quality

Fertility is a crucial aspect of reproductive health, and for women, egg productivity and quality play a vital role in conception. The number and quality of eggs naturally decline with age, but various lifestyle changes, diet improvements, and medical interventions can help maintain and enhance ovarian health. Whether you are planning for pregnancy now or preserving fertility for the future, here are some effective ways to boost egg productivity and quality.

1. Maintain a Balanced and Nutrient-Rich Diet

What you eat directly impacts your reproductive health. A fertility-friendly diet should include:

  • Antioxidants: Found in berries, nuts, and leafy greens, antioxidants help protect eggs from oxidative stress.

  • Healthy Fats: Avocados, olive oil, and nuts support hormonal balance and egg cell membrane integrity.

  • Protein Sources: Include lean meats, fish, eggs, and plant-based proteins like beans and lentils to promote healthy egg development.

  • Folic Acid & B Vitamins: Essential for cell division and DNA synthesis. Found in leafy greens, citrus fruits, and fortified grains.

  • Omega-3 Fatty Acids: Found in salmon, flaxseeds, and walnuts, they enhance egg quality and overall reproductive health.

2. Stay Hydrated

Drinking enough water is essential for circulation and nutrient transport to the ovaries. Dehydration can negatively affect egg development and hormone production.

3. Maintain a Healthy Weight

Being overweight or underweight can disrupt hormonal balance and ovulation. Maintaining a BMI within a healthy range supports regular ovulation and egg maturation.

4. Reduce Stress Levels

Chronic stress increases cortisol levels, which can interfere with reproductive hormones and egg development. Stress management techniques include:

  • Meditation & Yoga: Help regulate stress hormones and improve blood flow to reproductive organs.

  • Regular Exercise: Moderate physical activity boosts circulation and hormone regulation.

  • Adequate Sleep: 7-9 hours of quality sleep each night supports hormone balance and overall health.

5. Avoid Toxins and Harmful Substances

  • Reduce Caffeine & Alcohol: Excessive intake can negatively affect fertility.

  • Quit Smoking: Smoking accelerates ovarian aging and reduces egg quality.

  • Limit Exposure to Environmental Toxins: Pesticides, plastics (BPA), and heavy metals can harm egg health. Opt for organic foods and use BPA-free products.

6. Take Fertility-Boosting Supplements

Certain vitamins and supplements can enhance egg quality:

  • Coenzyme Q10 (CoQ10): Improves egg cell energy and mitochondrial function.

  • Vitamin D: Supports ovarian function and hormonal balance.

  • Zinc & Selenium: Help protect eggs from oxidative stress and improve overall reproductive health.

  • DHEA (Dehydroepiandrosterone): A precursor hormone that can help improve ovarian reserve in some cases (consult a doctor before use).

7. Consider Medical Interventions if Necessary

If you are struggling with fertility issues, consult a specialist who may recommend:

  • Hormonal Therapy: Helps regulate ovulation and improve egg development.

  • Ovulation Induction Medications: Clomiphene citrate or Letrozole can stimulate egg production.

  • IVF (In Vitro Fertilization): If natural conception is difficult, IVF can retrieve multiple eggs for fertilization.

  • PRP (Platelet-Rich Plasma) Therapy: An emerging treatment that may help rejuvenate ovarian function.

8. Monitor Your Ovarian Reserve

Regular fertility check-ups can help assess egg quality and quantity. Tests such as:

  • AMH (Anti-Müllerian Hormone) Test: Measures ovarian reserve.

  • FSH & Estradiol Tests: Assess ovarian function and hormone levels.

  • Antral Follicle Count (AFC) via Ultrasound: Provides insights into egg supply.

Conclusion

Improving egg productivity and quality requires a holistic approach that includes a healthy diet, lifestyle adjustments, and, if needed, medical assistance. By adopting these strategies, you can enhance your fertility potential and increase your chances of a successful pregnancy. If you are planning for the future, consider consulting a fertility specialist for personalized guidance on preserving and optimizing your reproductive health.

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