Last Update Date
13.01.2025

CALCIUM IONOPHORE THERAPY

CALCIUM IONOPHORE THERAPY


11 February 2025

Calcium ionophore therapy is a treatment method applied to ensure a healthy fertilization and to obtain a high pregnancy rate. In order to talk about a healthy fertilization, when the sperm enters the egg, the enzyme in the head part of the egg must be released into the egg and the amount of calcium inside must increase.

If the amount of folfolipase C in the sperm is low, the egg cannot be fertilized because without phospholipase, the calcium rate in the egg does not increase.

Calcium ionophore therapy is an application that increases the amount of calcium in the egg. In the calcium ionophore application, the egg and sperm are first fertilized by micro-injection. After this process, the eggs are kept in a calcium ionophore for a few minutes. The main purpose here is to increase the calcium level that needs to be increased in the egg. In other words, calcium ionophore therapy helps the fertilization of the egg by supporting the reactions that should start in the egg. So, what is calcium ionophore therapy and to whom is it applied? Now we will answer all these questions for you.



What is Calcium Ionophore? To Whom Is It Applied?

It is possible to define calcium ionophore therapy as an application that increases the amount of calcium in the egg. This treatment method is generally applied to the people we will list below. Those people;

Individuals with successive fertilization problems

If very few eggs or sperm are obtained

In cases where no fertilization can be achieved with micro-injection therapy

In patients with “globosperm” of all sperms

Calcium ionophore therapy is applied.



Who Is Fertilized With Calcium Ionophore?

In cases where embryo transfer cannot be performed due to the fertilization step not taking place during IVF treatment, activation of the eggs and fertilization are aimed by using calcium ionophore. Thus, calcium ionophore therapy is applied. With this treatment method, the problem of non-fertilization can be eliminated and treatment can be applied in couples who have non-fertilization problems. This treatment method is also applied to couples who have problems as a result of obtaining a very small amount of egg and sperm. Fertilization is performed with the calcium ionophore treatment method and a high pregnancy rate is obtained.

In this article, we have given the answers to all these questions for you, what is calcium ionophore therapy, to whom this treatment method is applied and in whom fertilization occurs as a result of the treatment.

It may interest you: What is infertility, what are its symptoms, what kind of treatment method is applied?

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