Last Update Date
21.10.2025

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Ear Nose Throat
In our Ear Nose and Throat Polyclinic, ear diseases such as ear infections, hearing loss, balance disorders and tinnitus, nasal congestion, nasal discharge, olfactory disorders, sinusitis, nasal diseases such as allergic rhinitis, throat diseases such as pharyngitis, tonsillitis, other rare diseases of the mouth and throat ; In addition to hoarseness, dysphagia and speech disorders, cancer diagnosis and treatment of the neck are performed. Our ENT polyclinic is equipped with devices and equipment that allow endoscopic examinations in addition to classical examination tools.

Nose Aesthetics (Rhinoplasty)
Rhinoplasty is an aesthetic operation performed to correct or reconstruct the appearance of the nose. Apart from visual purposes, rhinoplasty is also performed to eliminate structural defects that cause breathing problems. It is also a frequently performed surgery in the treatment of nasal fractures.
The size of the nose, shape and angle of the nose can be changed with Rhinoplasty (nose aesthetics), which is the most preferred operation among aesthetic surgeries and is performed to create a beautiful nose that is compatible with the face and liked by the person himself and his surroundings.
In which cases is rhinoplasty necessary?
• If the patient has aesthetic concerns
• If there are breathing problems due to various functional disorders
• In sinus problems
• In nasal fractures
• In case of cleft lip (with other operations)
• In severe facial burns
How Is Rhinoplasty Performed?
With the first examination to be performed by the surgeon, the patient's complaints, the desired visual changes and whether they are suitable for the nose or face structure are evaluated by sharing ideas between the doctor and the patient. With a detailed examination, it can be determined whether there is any problem in the nose that may prevent the rhinoplasty operation. In the absence of a structural problem, general health checks should also be carried out, and the presence of conditions that may interfere with the surgical operation, such as bleeding diseases, should be investigated. It is very important for the doctor and the patient to establish a good communication with the patient in terms of the shape changes to be made in the patients who are determined to be suitable for the operation, and to explain the patient's expectations to the doctor in a good way. The planning phase is completed by taking photographs of the nose from various angles.

When the day of the operation comes, general anesthesia is usually applied depending on the type of surgery. The duration of the operation also varies according to the procedures to be performed. On average, a rhinoplasty operation is expected to take approximately 1.5-2 hours. After the operation, which is performed by choosing the most suitable method for the patient, open or closed methods, the patients are discharged after being kept under observation for a certain period of time.
How long does the recovery process take in rhinoplasty?
After the rhinoplasty operation, it is of great importance to preserve the shape of the nose and the operation area in order to be successful in the treatment applications performed on the nose. Therefore, any trauma that will adversely affect the shape of the nose should be avoided. Apart from trauma, it is extremely important not to use heavy glasses, not to lie on your side or to apply pressure to the nose area for a period of time. After the surgery, resting adequately, especially for the first two or three days, and avoiding strenuous activities for a week will accelerate the healing process. In addition, medications prescribed by the physician should be used regularly. The control examinations given should not be interrupted, and if there is a dressing suggestion, they should be done regularly.
Today, rhinoplasty surgery gives extremely successful results thanks to the advanced techniques applied. Success in rhinoplasty means a nose that is both visually pleasing to the patient and performing its functions in a healthy way.

Who is suitable for Eyelid Aesthetics (Blepharoplasty)?

Eyelid aesthetics are mostly performed by individuals over the age of 35. It is possible for anyone with a medical need to have it done at any age. One of the first structures to show aging on the human face is the upper eyelid. Eyelid aesthetics (blepharoplasty) surgery cannot stop the ongoing aging of the eyelids; but the tired appearance on the face can be stopped for about 10 years.

How is upper eyelid aesthetics performed?

Upper eyelid aesthetics (blepharoplasty) or droopy eyelid surgery is the process of removing excess skin and fat tissue from the area due to the loss of tension in the skin. The surgical scar does not attract much attention as it will remain on the upper eyelid and will be open during the day. However, in order to avoid the scar, an incision is made from the eyelid fold line and aesthetic stitches are applied. Of course, this deformation of the skin does not occur only on the eyelid, so it gives better cosmetic results when applied together with forehead lift and eyebrow lifting operations.

In addition, interventions such as almond eye aesthetics along with upper eyelid aesthetics (blepharoplasty) are frequently preferred by patients.

How is lower eyelid aesthetics performed?

The fat pads located on the cheekbones atrophy (weak) with the effect of gravity along with the aging process. This causes signs of aging in the form of slumping or edema under the lower eyelid and prominent smile lines around the mouth. The lower eyelid should be evaluated by your physician and checked for bagging and sagging. The form of treatment should be evaluated. If surgery is required, the specialist physician should initiate the planning and process. In lower eyelid aesthetics, the surgical incision is made just below the eyelashes. The skin is lifted and the fat packets are removed. If the under-eye sunkenness continues after the surgery, an under-eye fat injection may be required after recovery.

How long does it take for Eyelid Aesthetics (Blepharoplasty) surgery and post-operative recovery?

After Eyelid Aesthetic Surgery, patients do not have serious pain. Movement is allowed, provided that it is nourished and not heavy. The patient, who is discharged on the same day, is evaluated again the next day and 5 days later. Stitches are often dissolving stitches. However, when necessary, the stitches are removed painlessly without waiting for them to dissolve. After the 5th day, it is allowed to shower and return to normal life. In order to reduce scars in Eyelid Aesthetics, scar reducing creams are sometimes recommended to patients.

Natural and artificial factors, especially aging, can cause the skin to lose its old appearance and become deformed. Surgical and non-surgical methods continue to be frequently preferred by people who are dissatisfied with their external appearance.
Hüma Hospital offers you health and beauty together in its Medical Aesthetics Clinic, which prioritizes professionalism and high-level technology.

BOTOX PROCESSES

What is Botox?

Botox , botulinum It is an abbreviation of the word toxin . Bacteria is a condensed type of protein. By acting on a substance called acetylcholine , which provides this communication between the brain and muscle , Botox prevents the contraction of small muscle groups that cause the appearance of wrinkles on the face and ensures that wrinkles are minimized.
It provides a more aesthetic appearance to the person by showing the effect of eliminating the appearance of wrinkled and old skin in a short time. Botox also provides expression design.
Because of the lines on the face, people who have an angry and stressful stance can easily get rid of this situation with botox .

How is Botox applied?

Botox application is done through a thin needle tip. Specially designed small injectors are used with a thin needle. The application is made to the muscle layer. During the Botox procedure, a slight burning sensation, like a needle stick, is felt. Other than that, no pain is felt. However, local anesthetic cream and ice are applied to sensitive individuals during the procedure.

How Long Does Botox Effect Last?

of Botox lasts up to 4-6 months. In repetitive botox applications, this period is prolonged in many patients. The effect of Botox does not end abruptly 4-6 months after it is made, it disappears over time. A person who has had botox for a long time will have fewer wrinkles than if he has never had botox, even after the procedure has lost its effect. That's why botox is also used as an anti-wrinkle treatment.

Facial Botox
Eye area Botox
Forehead Botox
Between Eyebrows Botox
Upper lip (Smoking lines) Botox
Lip Edge (sad face) Botox
Gummy Smile (The appearance of the gums when smiling) Botox
Upper Nose (Rabbit lines) Botox
Masseter (Chewing) Botox
Nefertiti (Neck and Decollete) Botox
Hands and palms Botox
Sweating Botox
Migraine Botox

FILLING PROCESSES

Nose Filling: It is a painless and painless procedure that provides an aesthetic nose appearance without the need for surgery in people who have problems such as curvature and symmetry in the nose area, droopy nose tip .

anesthetic cream is applied to the area to be applied, waiting for 15-20 minutes and the area is disinfected, and the filling material is injected under the skin in appropriate doses.

After this procedure, which lasts for an average of 1-1.5 years and takes about 15-20 minutes, the person can return to his daily life immediately.

The biggest advantage of nasal filling is that the desired shape can be given to the nose of the person. A better profile view can be obtained by filling the gaps in the main bone. In the same way, nasal tip deformities can be eliminated to a certain extent and the nose can be given a more upturned appearance.
Cheek-Cheek Filling : With the cheek filling technique, which is made to find practical and quick solutions to aesthetic problems on the face, volume deficiencies in the cheeks of the person can be successfully treated with an operation that takes 15 minutes. Hyaluronic acid filling , which is found in the natural structure of the skin, is generally preferred as a filling material.
Lip Filling : Lip augmentation, which is applied to add volume to the lips and increase their aesthetic appearance, is a painless filling process that takes 10-15 minutes.
Nasolabial Filling: Nasolabial lines , which are known as laugh lines among the people, appear more clearly when people laugh. With the nasolabial filling process, the appearance of deep pits is eliminated and the tissues in this area have a more vivid and fuller appearance.

Under-Eye Light Filling: Under-eye bags, bruises and swellings, depending on the genetic structure of the person, usually begin to become more pronounced in the 30s . With under-eye light filling, people's under-eyes get a healthy appearance without pain and pain. The permanence of this process, which is made by allowing the gel with a high water content of hyaluronic acid to dissolve in the body, is 1-1.5 years.

Chin and Jawline Filling:It is a method applied to people whose forward or backward stance in the chin impairs facial aesthetics or who want a more pronounced chin appearance. It is done by anesthetizing the person's chin area and injecting the appropriate dose of hyaluronic acid filler . The chin filling session takes about 15 minutes and the healing process is fast.

Temple Filling: It is a botox procedure that is performed to ensure facial harmony and makes the temples more pronounced .

PINK GLOW:
One of the most popular applications of the last period, which ensures the renewal of the skin, Paris Shine is one of the aesthetic applications performed to make the face shadow look younger and healthier.

How to Apply Paris Shine?

Local After skin cleansing, anesthetic cream is applied to sensitive individuals and waited for 20 minutes. It is then injected with a mesotherapy needle by forming a papule (with a slight swelling of the skin).
It can be applied to points of aging such as face, neck, décolleté and hands to give a fresher and brighter appearance. With the Paris glow, which can be repeated with certain sessions, the differences in your skin will show itself as vitality, brightness and youth, and you will feel more beautiful.

Face Lift with Rope Strap (French Strap): It is one of the non-surgical face rejuvenation methods with flexible ropes compatible with the human body to raise the tissue under the skin surface. People who are dissatisfied with their facial features and have complaints of wrinkles and sagging can make their choices with expert opinion Rope Strap alternatives according to their skin conditions.

Rope Axis Application Areas

In this method, although the application areas of the rope hanger may vary according to mimic movements, they are mostly the same. We can list the rope suspension application areas on the face and body as follows:

cheeks
Gill
cheekbones
oval line of the face
forehead lines
crow's feet
Kas region
Neck

Process time

The patient does not feel pain or pain during the rope suspension application under local anesthesia.
Depending on the procedure to be performed, the time may vary. However, it is usually completed in 20 minutes.
There is no need for stitches in the rope suspension application applied to the patient.
During the procedure, it is ensured that the threads are attached to the ear inside the head.
In case of stretching for the body, rope hangers are attached to different areas.
No clinical rest or home rest is required after the procedure.
Individuals can return to their daily life.

Every woman wants to have beautiful, clean and smooth skin. Laser epilation, which has facilitated the work of not only women but also men in recent years, is an extremely effective method applied to permanently remove unwanted hair follicles and unwanted hair. The fact that it has the quality of use in all seasons and that it does not have any roughness has also increased its degree of effectiveness. The most distinctive feature of the ice laser is that it offers many methods as a whole and gives the expected results quickly.

The Ice laser epilation device, which we offer in our hospital, is a laser epilation method that is applied every season with an extremely low level of pain and technological systems are used. Thanks to the hair follicles that can be destroyed by laser, you will have clearly observed that your hair growth or hair growth problems have decreased visibly. Laser epilation is an effective and safe treatment to permanently get rid of unwanted hair. An important point to note in laser epilation applications that both men and women can apply is that the laser procedure is performed by trained specialists in a hospital environment under the control of a doctor. People with darker skin tones may experience hyperpigmentation and scarring, while people with lighter skin tones may experience temporary redness and swelling. You can have laser epilation in our hospital accompanied by a specialist doctor and esthetician.
If you are looking for a hassle-free solution for your epilation needs, the Ice laser epilation technique, which you can safely choose for four seasons, may be the perfect option for you.

Aesthetic Plastic and Reconstructive Surgery
Aesthetic Procedures mean taking a step towards the desired innovation in our body, both for health reasons and to look better. Natural-looking results and the look you dream of can be achieved with medical aesthetic applications and surgical procedures that include personalized solutions that we perform at Hüma Aesthetics Plastic and Reconstructive Surgery Clinic.

Breast plastic surgery (enlargement-reduction-lift), nose plastic surgery (rhinoplasty), body shaping (liposuction, lipectomy, abdominoplasty), face lift-renewal, eyelid surgery (blepharoplasty), auricle correction (protruding ear) are frequently performed aesthetics. between operations. The services provided by our Plastic Surgery branch can be listed as follows.

SURGICAL PROCEDURES
  • Nose aesthetics (Rhinoplasty)
  • Eyelid aesthetics (Blepharoplasty)
  • Facial Rejuvenation with fat injection
  • Hollywood cheek (Bichectomy)
  • Ear Aesthetics
  • Dimple making
  • Mid-Face and neck lift
  • Almond Eye and Brow Lift
  • Forehead and Temple Aesthetics (Temporal lift)
  • Breast aesthetics (Enlargement-Reduction-Lift)
  • Breast construction after cancer surgery
  • Gynecomastia surgery
  • Abdominoplasty
  • Arm lift
  • Leg stretching
  • Fat Injection (Liposuction)
  • Butt Aesthetics
  • Body shaping (tightening) after weight loss
  • Genital aesthetics

NON-SURGICAL PROCEDURES
  • Fillings
  • Botox applications
  • Wrinkle treatment
  • French Lift
  • Paris Sparkle
  • Lip aesthetics
  • Over-sweating treatment
  • Regional Weight Loss (Enzymatic Lipolysis)
  • Cleft palate and lip repair
  • Congenital anomalies
  • Scar and Burn Treatments
  • Skin tumors and their treatment
  • Facial Aesthetics

PREIMPLANTATION GENETIC DIAGNOSIS
In recent years, developments in genetics allow genetic analysis to be carried out on embryos developed in vitro by in vitro fertilization  ethods and the placement of selected healthy embryos in the uterus of the mother before pregnancy occurs. This method is called pre- regnancy genetic diagnosis (Preimplantation Genetic Diagnosis-PGD).
One of the most important application areas of the PGT technique embryos that do not have a genetic disease but may not have a genetic disorder in their chromosomes.
These disorders are more common in women of advanced age (35 years and older). This situation may result in infertility as it both reduces the chance of attachment of the embryo (implantation) and may cause unwanted abortions. As a matter of fact, 40 out of every 100 pregnancies in women aged 39 and over have problems that occur due to a numerical chromosomal disorder
 
The aim of PGD is to increase implantation rates, reduce spontaneous abortions and increase healthy baby birth rates by selecting hromosomally normal embryos. Indeed, the miscarriage rate, which can reach up to 23 percent in normal pregnancy due to chromosomal disorders, may decrease to 9 percent after PGD.
 
Pre-pregnancy genetic diagnosis is performed by taking 1 or 2 cells from embryos developed as a result of fertilization of egg and sperm cells obtained from mother and father candidates in laboratory environment. Special methods called Fluorescence In Situ Hybridization (FISH), Microarray-based comparative genomic hybridization (aCGH) or Polymerase Chain Reaction (PCR) are used for genetic diagnosis. Diagnosis of numerical chromosomal disorders such as monosomy or trisomy (Down syndrome and other trisomies) and single gene diseases (such as hemophilia, Mediterranean anemia, cystic fibrosis, muscular dystrophies) in the baby to be born is possible with PGD. Thus, healthy babies are born by transferring disease-free, healthy embryos to the expectant mother.
 
DIAGNOSIS BEFORE PREGNANCY
 
  • In couples with a genetic or hereditary disease carrier,
  • In couples who have a child or children with a previous genetic disease,
  • For the purpose of HLA genotyping (tissue typing),
  • In the identification of diseases showing genetic predisposition (tendency)
  • Women in the advanced age group (37 years and over) who have been accepted for assisted reproductive techniques,
  • In couples with recurrent early pregnancy miscarriages,
  • In couples who could not achieve pregnancy with assisted reproductive techniques despite multiple applications or who lost their pregnancy due to miscarriage,
  • It is applied in cases of chromosomal disorders or genetic diseases associated with severe male infertility.
 
HOW IS THE PGT TEST DONE?
 
  • Whether the patient is suitable for PGD is evaluated by the reproductive health specialist, genetic counselor and the doctor of the related disease.
  • The couple is prepared for the IVF procedure.
  • The egg taken from the mother is fertilized in the laboratory with the sperm taken from the father.
  • 1-2 blastomere cells are removed from the obtained embryo by biopsy by embryologists
  • Cells obtained by biopsy are prepared and tested according to the method to be applied.
  • Embryos with genetic diseases or chromosomal disorders are selected and discarded and healthy embryos are transferred to the mothers womb.

It is a method of activating eggs and ensuring fertilization by using calcium ionophore (calcium ionophore) in cases where embryo transfer cannot be performed due to lack of fertilization during IVF treatment.
 
In the calcium ionophore application, first the egg and sperm are fertilized by micro-injection (ICSI); Then the eggs are kept in a medium containing calcium ionophore for a while. The main purpose here is to artificially increase the calcium level, which should increase in the egg after the sperm enters the egg. In other words, by supporting the reactions that should start in the egg, the egg is forced to be fertilized. With this procedure, a healthy fertilization and therefore a high pregnancy rate can be achieved.
Calcium ionophore therapy has been shown to be successful in the following situations:

  • In patients with “globosperm” of all sperms
  • If very few eggs or sperm are obtained
  • Recurrent fertilization (fertilization) failures
  • In cases where no fertilization can be achieved with micro-injection therapy

In patients with low sperm viability, quantity, number and structural quality, microfluidic technology, also known as the "chip baby method", ensures that the best quality sperm cells are selected by competing with each other in a way similar to the natural environment in the uterus, and ICSI is defined in in vitro fertilization treatment. With the application, it is left into the egg cell by microinjection method.

In this method, sperm cells with the best structural form, genetics and physiology are selected without causing cell damage, since techniques such as centrifugation (settling), vortex (mixing with high vibration) or mixing with a pipette are not applied to the sperm cells, which can physically damage the sperm cells. In classical preparation methods, sperm cells are prepared in a shorter time without being subjected to manipulation by skipping processes such as washing, flotation, gradient (grading), centrifugation (precipitation at high speeds). Thus, the sperm cells with the best DNA quality and physiologically are selected by themselves, and the sperm cells that pass this pre-screening are again screened under the microscope and the sperm cells of excellent quality are used for microinjection.

The above-mentioned classical preparation methods cause sperm cells to undergo respiratory stress, known as oxidative stress, and it has been scientifically proven that this can also cause DNA damage in healthy sperm cells. Better quality embryos are tried to be obtained with sperm cells that have been proven to be of the best quality by scientific data, and thus embryos with the highest potential for implantation (attachment) and development are obtained. The average total mobility in suckling samples taken from male individuals with microchip technology increased by 1.7 times.
The sperm cells obtained by this method were found 3 times faster than the classical preparation methods, and the forward motile sperm cells increased 3.8 times.

In recent years, intralipids have been used to reorganize the immune systems of candidates, especially in recurrent IVF failures. Intralipids consist of an oil emulsion of soybean oil, egg phospholipids and glycerin. Intralipid serum application provides intrauterine balance by affecting the immune system that prevents the embryo from adhering to the expectant mother. This application, which is given to patients intravenously in the form of serum, is carried out at certain intervals during the ovulation induction, on the day of embryo transfer and in the following period.

While deciding on intralipid serum supplementation in line with the treatments we planned with the principle of personalized treatment, the physical and biological characteristics of the couples, recurrent IVF failures and infertility histories are taken into account.

Embryo pool technique is the method of freezing the embryos obtained by collecting two or more eggs (OPU) and transferring the accumulated embryos by thawing them together. It is possible to make an embryo pool by collecting eggs multiple times using little medication (seminatural cycle) or without using drugs (natural cycle) and transferring embryos that have reached advanced developmental stages, such as blastocyst stage. This application is recommended for couples with reduced egg reserve or concomitant IVF failures. With the embryo pool method, it will be possible to achieve more treatment with less cost, a higher chance of pregnancy per embryo transfer, and reduce the negative effects of infertility on couples.

EDUCATION

  • Specialization: Erciyes University Faculty of Medicine, Department of Neurosurgery
  • Medical Education: Atatürk University Faculty of Medicine

WORK EXPERIENCE

  • 2025 – Present: Private Hüma Hospital
  • 2009 – Present: Professor – Erciyes University Faculty of Medicine, Department of Neurosurgery
  • 2001-2009: Associate Professor – Erciyes University Faculty of Medicine, Department of Neurosurgery
  • 1991-2001: Assistant Professor – Erciyes University Faculty of Medicine, Department of Neurosurgery
  • 1985-1991: Erciyes University Faculty of Medicine, Department of Neurosurgery
  • 1983-1985: Anamur SSK Health Station

AREAS OF INTEREST

  • Congenital brain and spinal anomalies
  • Hydrocephalus (fluid accumulation in the brain)
  • Lumbar and cervical hernia surgeries
  • Spinal canal stenosis surgery
  • Brain, spinal cord, and cyst tumor surgeries
  • Brain trauma and hemorrhages

SCIENTIFIC PUBLICATION BOARD MEMBERSHIPS

  • Turkey Clinics Journal of Medical Sciences
  • Fırat Medical Journal

He has a total of 76 scientific publications (50 international, 26 national) and 131 congress presentations (6 international, 125 national). Additionally, he has authored 11 review articles and contributed 11 chapters in 6 books.

He has been an invited speaker 78 times at national scientific congresses, conferences, symposiums, and courses. In 2005, he organized one scientific meeting and served on the organizing committee of 7 congresses and scientific meetings.

Furthermore, he served as the Congress Secretary of the Turkish Neurosurgery Association Scientific Congress in 2021. He has worked as a special issue editor for a neurosurgery journal and as an editor for the pediatric section of a neurosurgery book.

He has supervised 6 doctoral theses, and his scientific studies have received citations.

SCIENTIFIC PUBLICATIONS

I- Articles

A- Published in Journals Indexed in SSCI, AHCI, or SCI

Koç RK, Akdemir H, Kandemir O, Paşaoğlu H, Öktem İS, Paşaoğlu A: The therapeutic value of naloxone and mannitol in experimental focal cerebral ischemia. Res Exp Med 194:277-285, 1994
Akdemir H, Selçuklu A, Paşaoğlu A, Öktem İS, Kavuncu İA: Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase. Neurosurg Rev 18:95-100, 1995
Paşaoğlu A, Kurtsoy A, Koç RK, Kontaş O, Akdemir H, Öktem İS, Selçuklu A, Kavuncu A: Cranioplasty with bone flaps preserved under the scalp. Neurosurg Rev 19:153-156, 1996
Koç RK, Akdemir H, Öktem İS, Meral M, Menkü A: Acute subdural hematoma; outcome and outcome prediction. Neurosurg Rev 20:239-244, 1997
Karaküçük Eİ, Paşaoğlu H, Paşaoğlu A, Öktem S: Endogenous neuropeptides in patients with acute traumatic head injury II. Neuropeptides 31:259-263, 1997
Öktem İS, Akdemir H, Koç K, Menkü A, Tucer B, Selçuklu A, Turan C: Migration of abdominal catheter of ventriculoperitoneal shunt into the scrotum. Acta Neurochir 140:167-170, 1998
Koç RK, Paşaoğlu A, Menkü A, Öktem İS, Meral M: Extradural hematoma of the posterior cranial fossa. Neurosurg Rev 21:52-57, 1998
Koç RK, Akdemir H, Karaküçük EI, Öktem İS, Menkü A: Effect of methylprednisolone, tirilazad mesylate, and vitamin E on lipid peroxidation after experimental spinal cord injury. Spinal Cord 37:29-32, 1999
Koç RK, Kurtsoy A, Paşaoğlu H, Karaküçük EI, Öktem İS, Meral M: Lipid peroxidation and edema in experimental brain injury: Comparison of treatment with methylprednisolone, tirilazad mesylate, and vitamin E. Res Exp Med 199:21-28, 1999
Akdemir H, Kontaş O, Öktem İS, Tucer B, Kafadar H, Paşaoğlu A: A new subtype of meningioma. Neurosurg Rev 22:50-53, 1999
Akdemir H, Kurtsoy A, Öktem İS, Menkü A, Koç RK, Tucer B: Failure of open third ventriculostomy for shunt infections in infants. Pediatr Neurosurg 30:305-309, 1999
Öktem İS, Menkü A, Akdemir H, Kontaş O, Kurtsoy A, Koç RK: Therapeutic effect of tirilazad mesylate (U-74006F), mannitol, and their combination on experimental ischemia. Res Exp Med 199:231-242, 2000
Öktem İS, Akdemir H, Kurtsoy A, Koç RK, Menkü A: Hemilaminectomy for the removal of spinal lesions. Spinal Cord 38:92-96, 2000
Kurtsoy A, Canbay S, Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Effect of EGb-761 on vasospasm in experimental subarachnoid hemorrhage. Res Exp Med 199:207-215, 2000
Kurtsoy A, Öktem İS, Koç RK, Menkü A, Akdemir H, Tucer B: Surgical treatment of thalamic hematomas via the contralateral transcallosal approach. Neurosurg Rev 24:108-113, 2001
Akdemir H, Aşık Z, Paşaoğlu H, Karaküçük İ, Öktem İS, Koç RK: The effect of allopurinol on focal cerebral ischemia: an experimental study in rabbits. Neurosurg Rev 24:131-135, 2001
Koç RK, Menkü A, Akdemir H, Tucer B, Kurtsoy A, Öktem İS: Cervical spondylotic myelopathy and radiculopathy treated by oblique corpectomies without fusion. Neurosurg Rev 27:252-258, 2004
Kurtsoy A, Menkü A, Tucer B, Öktem İS, Akdemir H, Koç RK: Transbasal approaches: surgical details, pitfalls, and avoidances. Neurosurg Rev 27:267-273, 2004
Kurtsoy A, Menkü A, Tucer B, Öktem İS, Akdemir H: Neuronavigation in skull base tumors. Minim Invas Neurosurg 48:7-12, 2005
Menkü A, Akdemir H, Durak AC, Öktem İS: Successful surgical excision of juvenile-type spinal arteriovenous malformation in two stages following partial embolization. Minim Invas Neurosurg 48:57-62, 2005
Akdemir H, Öktem S, Menkü A, Tucer B, Tuğcu B, Günaldı Ö: Image-Guided Microsurgical Management of Small Arteriovenous Malformations: Role of Neuronavigation and Intraoperative Doppler Sonography. Minim Invas Neurosurg 50:163-169, 2007
Öktem İS, Menkü A, Özdemir A: When should ventriculoperitoneal shunt placement be performed in cases with myelomeningocele and hydrocephalus? Turkish Neurosurg 18:387-91, 2008
Menkü A, Koç R.K, Öktem IS, Tucer B, Kurtsoy A: Laminoplasty with Miniplates for Posterior Approach in Thoracic and Lumbar Intraspinal Surgery. Turkish Neurosurg 20:27-32, 2010
Köksal V, Öktem İS: Ventriculosubgaleal shunt procedure and its long-term outcomes in premature infants with post-hemorrhagic hydrocephalus. Childs Nerv Syst 26:1505-1515, 2010
Küçük A, Tümtürk A, Gergin İŞ, Oral Ş, Görkem SB, Kurtsoy A, Madenoğlu H, Öktem İS: The Management of Blood Loss in Non-Syndromic Craniosynostosis Patients Undergoing Barrel Stave Osteotomy. Turkish Neurosurg 27:138-141, 2017
Yay A, Goktepe Ö, Bahadir A, Özdamar S, Öktem IS, Çoruh A, Baran M: Assessment of markers expressed in human hair follicles according to different skin regions. Adv Clin Exp Med 27:929–939, 2018
Köksal V, Mercantepe T, Tümkaya M, Oktem IS: Less use of bipolar cautery can prevent post-laminectomy epidural fibrosis. Turkish Neurosurg 30:217-224, 2020
Kamaşak B, Ulcay T, Küçük A, Karaman F, İpekten F, Öktem İS, Aycan K: A new supportive approach in the diagnosis of Chiari malformation type 1 in pediatric patients. Childs Nerv Syst 39:1581-1587, 2023

B- Published in Peer-Reviewed National and International Journals

[List continues with national and international peer-reviewed journals...]

II- Other Studies (Technical Notes, Comments, Case Reports, Letters to the Editor, etc.)

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A- Articles Published in Journals Indexed in SSCI, AHCI, or SCI

Paşaoğlu A, Orhon C, Akdemir H, Uzunoğlu H, Öktem S, Yardım Ş: Subperiosteal intraorbital hematoma following minor head trauma. A case report. Acta Neurochir 97:83-85, 1989
Akdemir H, Paşaoğlu A, Ekinciler ÖF, Selçuklu A, Karaküçük S, Öktem İS: Unilateral naso-orbital meningocele and bilateral congenital fistulae of the lacrimal passages. Acta Ophtal 69:680-683, 1991
Öktem İS, Selçuklu A, Kurtsoy A, Kavuncu İA, Paşaoğlu A: Migration of a bullet in the spinal canal. A case report. Surg Neurol 44:548-550, 1995
Kurtsoy A, Paşaoğlu A, Koç RK, Öktem İS, Kontaş O: Cerebellopontine angle germinoma. A case report. Neurosurg Rev 19:127-130, 1996
Kurtsoy A, Koç RK, Öktem İS, Kontaş O, Selçuklu A, Paşaoğlu A: Ganglioglioma of conus medullaris. A case report. Neurosurg Rev 20:55-58, 1997
Akdemir H, Öktem İS, Koç RK, Kavuncu İ: Postoperative intraradicular lumbar disc herniation. A case report. Neurosurg Rev 20:71-74, 1997
Selçuklu A, Kurtsoy A, Öktem İS, Koç RK, Kavuncu İA: Postoperative mutism after the clipping of a distal anterior cerebral artery aneurysm. A case report. Neurosurg Rev 20:214-216, 1997
Koç RK, Paşaoğlu A, Kurtsoy A, Öktem İS, Kavuncu İA: Acute spontaneous subdural hematoma of arterial origin. A report of five cases. Surg Neurol 47:9-11, 1997
Öktem İS, Akdemir H, Sümerkan B, Koç RK, Menkü A, Tümtürk F: Cerebellar abscess due to Nocardia asteroides. Acta Neurochir 141:217-218, 1999
Kurtsoy A, Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Successful surgical treatment of a thalamic hydatid cyst with a contralateral transcallosal approach. Pediatr Neurosurg 31:96-99, 1999
Koç RK, Kurtsoy A, Öktem İS, Akdemir H: Growing skull fracture of the orbital roof. Pediatr Neurosurg 30:35-38, 1999
Koç RK, Akdemir H, Öktem İS, Menkü A: Intradural lumbar disc herniation: Report of two cases. Neurosurg Rev 24:44-47, 2001
Koç RK, Akdemir H, Öktem İS, Kurtsoy A, Menkü A: Posterolaterally displaced type IIA odontoid fractures. Neurosurg Rev 24:143-146, 2001
Menkü A, Kurtsoy A, Tucer B, Öktem İS, Akdemir H: The surgical management of traumatic C6-C7 spondyloptosis in a patient without neurological deficits. A case report. Minim Invas Neurosurg 47:242-244, 2004
Akdemir H, Öktem İS, Tucer B, Menkü A, Başaslan K, Günaldı Ö: Intraoperative microvascular Doppler sonography in aneurysm surgery. Minim Invas Neurosurg 49:312-316, 2006
Baykan Z, Öktem İS, Çetinkaya F, Naçar M: Physician exposure to violence: A study performed in Turkey. Int J Occup Saf Ergon 21(3):291-297, 2015

B- Articles Published in Peer-Reviewed National and International Journals

Paşaoğlu A, Yardım Ş, Öktem İS, Selçuklu A, Akdemir H, Koç K: Acute spontaneous arterial subdural hematoma. A case report and review of the literature. Turkish Neurosurg 2:44-48, 1991
Kurtsoy A, Paşaoğlu A, Koç RK, Öktem İS, Kavuncu İA: Calvarial osteogenic sarcoma developing on Paget’s disease. Erciyes Med J 16:186-189, 1994
Öktem İS, Akdemir H, Paşaoğlu A, Kurtsoy A, Selçuklu A: Hydatid cyst of the posterior fossa. A case report. Erciyes Med J 16:303-306, 1994
Kurtsoy A, Paşaoğlu A, Koç RK, Öktem İS: Acute brain swelling during the evacuation of an intracerebral hematoma caused by primary progressive contralateral subdural hematoma: A case report. Erciyes Med J 17:77-80, 1995
Menkü A, Tucer B, Kurtsoy A, Öktem İS, Göçmez C, Akdemir H: Spontaneous cerebrospinal fluid rhinorrhea associated with temporal lobe meningoencephalocele in the lateral sphenoid sinus in an adult. Turkish Neurosurg 14:76-79, 2004

C- Articles Published in Non-Peer-Reviewed Journals (Faculty, Institute, Research Center Journals, and Encyclopedic Entries)

Durak AC, Özcan N, Kırnap M, Öktem İS: Brucella spondylodiscitis. Computed Tomography Bulletin 3:41-43, 1995
Madenoğlu H, Bilen A, Öktem İS, Akın A, Boyacı A: Anaesthetic management of vein of Galen aneurysms. A case report. Surgical Medicine Archives 4:193-195, 1997
Kurtsoy A, Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Akinetic mutism due to recurrent obstructive hydrocephalus. Surgical Medicine Archives 3:181-184, 1998

I- Review Articles

Öktem İS, Göçmez C: Spinal tumors in childhood. Turkiye Klinikleri J Pediatr Sci 3:80-85, 2007
Öktem İS, Göçmez C: Emergency neurosurgical approach in patients with mild and moderate head trauma. Turkiye Klinikleri J Surg Med Sci 3:27-31, 2007

III- Presented and Published Conference Papers

A- International Conferences

Ünal A, Öktem İS, Çetin M, Çelik F, Akdemir H: Activated Protein C Resistance with Deep Venous Thrombosis, Recurrent Pulmonary Embolism, and Cerebral Hemorrhage. A case report. XIV Meeting of the International Society of Haematology, 30 Aug-4 Sept 1997, Stockholm, Sweden (Poster)
Koç RK, Öktem İS, Kurtsoy A, Tucer B, Akdemir H: Adult diastematomyelia. 12th World Congress of Neurosurgical, 16-20 Sept 2001, Sydney, Australia (Poster)
Kurtsoy A, Akdemir H, Menkü A, Tucer B, Öktem İS, Koç RK: Neuronavigation in skull base tumors. 12th World Congress of Neurosurgical, 16-20 Sept 2001, Sydney, Australia (Poster)

B- National

Paşaoğlu A, Orhon C, Öktem İS, Uzunoğlu H, Akdemir H: Surgical Treatment in Pott's Abscesses. Turkish Neurosurgery Association Scientific Congress, May 1989, Antalya (Oral Presentation)

Paşaoğlu A, Orhon C, Öktem İS, Uzunoğlu H, Akdemir H: Surgical Approach in Thoracolumbar Trauma. Turkish Neurosurgery Association Scientific Congress, May 1989, Antalya (Oral Presentation)

Öktem İS, Paşaoğlu A, Patıroğlu TE, Selçuklu A, Akdemir H, Kılıç H: The Effect of Hyaluronidase in Experimental Brain Abscesses and Investigation of Its Mechanism. Turkish Neurosurgery Association Scientific Congress, May 21-26, 1991, Çeşme (Oral Presentation)

Bozkır MG, Aycan K, Öktem İS: Variations of the Circulus Arteriosus Cerebri. Anatomy Congress, June 27-30, 1991, Bursa (Oral Presentation)

Öktem İS, Paşaoğlu A, Akdemir H, Selçuklu A, Koç RK, Kurtsoy A: Prognosis of Minor Head Trauma. 10th Gevher Nesibe Medical Days, March 11-14, 1992, Kayseri (Oral Presentation)

Kök AH, Güraksın A, Öktem İS, Öztürk S: Retrospective Evaluation of Forensic Cases Related to Neurosurgery. 10th Gevher Nesibe Medical Days, March 11-14, 1992, Kayseri (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Meral M, Menkü A: Prognosis and Prognostic Factors in Acute Subdural Hematomas. Turkish Neurosurgery Association Scientific Congress, May 24-28, 1996, Çeşme (Oral Presentation)

Selçuklu A, Kavuncu İA, Koç RK, Alper M, Öktem İS, Menkü A: The Effect of Heparin on Capsule Formation in Experimental Brain Abscesses. Turkish Neurosurgery Association Scientific Congress, May 24-28, 1996, Çeşme (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Selçuklu A, Tucer B: Frequency of Transient Stenosis in Middle and Anterior Cerebral Arteries in Meningitis and Its Relationship with Clinical Findings. Turkish Neurosurgery Association Scientific Congress, May 16-20, 1997, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A: Intradural Lumbar Disc Herniation; Presentation of Two Cases. Turkish Neurosurgery Association Scientific Congress, May 16-20, 1997, Antalya (Poster Presentation)

Öktem İS, Akdemir H, Koç K, Menkü A, Tucer B, Selçuklu A: Migration of Ventriculoperitoneal Shunt into the Scrotum. Turkish Neurosurgery Association Scientific Congress, May 16-20, 1997, Antalya (Oral Presentation)

Koç RK, Paşaoğlu A, Menkü A, Öktem İS, Meral M: Posterior Cranial Fossa Epidural Hematomas. Turkish Neurosurgery Association Scientific Congress, May 16-20, 1997, Antalya (Oral Presentation)

Öktem İS, Selçuklu A, Koç K, Meral M, Menkü A, Akdemir H: Comparison of Aspiration + Drainage and Excision in the Treatment of Brain Abscesses. Turkish Neurosurgery Association Scientific Congress, May 16-20, 1997, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Diastematomyelia. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Poster Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B: Unilateral Hemilaminectomy in Spinal Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Poster Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Tethered Cord Syndrome. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Kontaş O, Tucer B, Menkü A, Tümtürk F: A New Subgroup of Meningiomas: Case Report. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Poster Presentation)

Koç RK, Akdemir H, Karaküçük Eİ, Öktem İS, Menkü A: The Effects of Methylprednisolone, Tirilazad Mesylate, and Vitamin E on Lipid Peroxidation in Experimental Spinal Cord Injury. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B: Syringomyelia. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B: Transcallosal Approach to Third Ventricular Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Selçuklu A: Outcome Analysis of Ventriculoperitoneal Shunt Infections. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Selçuklu A: Analysis of Posterior Cranial Fossa Epidural Hematomas. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Long-Term Follow-up of Patients with Chiari Malformation Type 1. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: Effectiveness of Various Surgical Techniques in the Treatment of Spinal Cord Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Role of Stereotactic Biopsy in Brain Tumor Diagnosis. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Evaluation of Surgical Approaches in Aneurysm Cases. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Pediatric Neurosurgery Cases: A Retrospective Analysis. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: Treatment and Follow-up of Hydrocephalus Patients. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Long-Term Results of Spinal Cord Decompression Surgeries. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Postoperative Outcomes of Brainstem Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Surgical Treatment of Cervical Spine Fractures. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: Factors Affecting Survival in Glioblastoma Patients. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Analysis of Cranial Trauma Cases in a Neurosurgical Unit. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Clinical and Radiological Findings in Pituitary Adenomas. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: The Role of Endoscopic Surgery in Neurosurgery. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Surgical Approaches to Pineal Region Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Neurosurgical Interventions in Pediatric Epilepsy. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: Evaluation of Postoperative Complications in Spinal Surgeries. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Koç RK, Akdemir H, Öktem İS, Menkü A, Tucer B, Kontaş O: Outcome of Patients with Cervical Spondylotic Myelopathy. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Öktem İS, Akdemir H, Koç RK, Menkü A, Tucer B, Kontaş O: Neurosurgical Management of Intramedullary Spinal Cord Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

Akdemir H, Öktem İS, Koç RK, Menkü A, Tucer B, Kontaş O: Surgical Strategies in Complex Cranial Base Tumors. Turkish Neurosurgery Association Scientific Congress, May 15-19, 1998, Antalya (Oral Presentation)

VI- Book

A- Contribution at the Chapter Level (National)

Öktem İS: Head Trauma. Sözüer E (ed), Emergency Aid and Trauma Handbook.
Feryal Printing, Ankara, 1977, pp. 120-150.

Öktem S, Menkü A: Spinal Neuroendoscopy. Aksoy K, Palaoğlu S, Pamir N, Tuncer (Eds). Basic Neurosurgery. Ankara, Buluş, 2005, pp. 1021-1025.

Öktem İS, Kamaşak K, Doğu Y: Head Trauma. Sözüer E, İkizceli İ (Eds), Trauma Handbook. Nobel Bookstore, Adana, 2011, pp. 451-491.

Öktem İS: Cranial Dermal Sinus. Baykaner MK, Erşahin Y, Mutluer MS, Özek MM (Eds), Pediatric Neurosurgery. Ankara, Buluş, 2014, pp. 361-364.

Öktem İS: Mechanism and Pathophysiology of Head Trauma. Baykaner MK, Erşahin Y, Mutluer MS, Özek MM (Eds), Pediatric Neurosurgery. Ankara, Buluş, 2014, pp. 689-695.

Öktem İS: Pathophysiology and Biomechanics of Pediatric Spinal Trauma. Baykaner MK, Erşahin Y, Mutluer MS, Özek MM (Eds), Pediatric Neurosurgery. Ankara, Buluş, 2014, pp. 749-754.

Şahin A, Öktem İS: Neural Tube Defects. Küçük A (Ed), General Neurosurgery Textbook. Kimlik Publishing, Kayseri, 2022, pp. 69-84.

Durmuş NA, Öktem İS: Benign Intracranial Cysts. Küçük A (Ed), General Neurosurgery Textbook. Kimlik Publishing, Kayseri, 2022, pp. 85-98.

Şahin A, Öktem İS: Craniosynostosis. Küçük A (Ed), General Neurosurgery Textbook. Kimlik Publishing, Kayseri, 2022, pp. 122-133.

Durmuş NA, Öktem İS: Hydrocephalus. Küçük A (Ed), General Neurosurgery Textbook. Kimlik Publishing, Kayseri, 2022, pp. 137-159.

Şahin A, Öktem S: How to Perform Ventriculoperitoneal Shunt Surgery? Avcı E (Ed), Basic Neurosurgery, Ankara, Buluş, 2023, pp. 1917-1923.

Contribution as a Special Issue Editor in a Journal (National)

Editor of the Special Issue on Neurosurgery-Hydrocephalus, Türkiye Klinikleri, Vol. 5, Issue 1, 2015.

Contribution as a Book Editor (National)

Basic Neurosurgery, Turkish Neurosurgery Association Publications, No:29, Pediatric Neurosurgery Section Editor, 2023.


EDUCATION, ADMINISTRATIVE, AND SCIENTIFIC ACTIVITIES

I- Invited Speaker

A- At National Congresses, Conferences, and Symposiums

  • May 11-12, 1996: Erciyes University Faculty of Medicine, Department of Emergency Medicine, and Kayseri Health Directorate, "Postgraduate First Aid and Emergency Course," Kayseri.

  • October 9, 2000: Workshop on "Navigation Applications in Neurosurgery," Erciyes University Faculty of Medicine, Neurosurgery Department, Kayseri.

  • April 4, 2002: Erciyes University Faculty of Medicine / Postgraduate Education Program
    Panel: Neural Tube Defects

    • Prof. Dr. M. Adnan Öztürk
    • Assoc. Prof. Dr. Suat Öktem
    • Asst. Prof. Dr. Deniz Demirci
    • Asst. Prof. Dr. M. Hakan Poyrazoğlu
  • January 23, 2003: Erciyes University Faculty of Medicine / Postgraduate Education Program
    Panel: Complications of Sinusitis

    • Prof. Dr. Yaşar Ünlü
    • Assoc. Prof. Dr. Suat Öktem
  • September 25-28, 2003: IV. Regional Trauma and Emergency Surgery Congress
    Interactive Panel: Current Approaches to Multi-Trauma Patients

    • Moderator: Prof. Dr. Recep Güloğlu
    • Prof. Dr. Ali Baktır
    • Assoc. Prof. Dr. Fahri Oğuzkaya
    • Assoc. Prof. Dr. Suat Öktem
    • Asst. Prof. Dr. İbrahim İkizceli
  • April 13-17, 2005: 13th National Neonatology Congress, Kayseri
    Panel: Post-Hemorrhagic Hydrocephalus

    • Prof. Dr. Nihal Oygür
    • Prof. Dr. Barboros Ilıkkan
    • Assoc. Prof. Dr. Suat Öktem
  • April 27-30, 2005: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
    Pediatric Neurosurgery Training Course III Term - II Course, Kayseri

    • Topic Presented: Visual Pathway Tumors
  • April 27-30, 2005: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
    Pediatric Neurosurgery Training Course III Term - II Course, Kayseri

    • Topic Presented: Neuronavigation
  • June 14-17, 2005: National Trauma and Emergency Surgery Association – Erciyes University Faculty of Medicine
    40th Trauma and Resuscitation Course, Kayseri

    • Topic Presented: Head Trauma
  • December 13-16, 2005: National Trauma and Emergency Surgery Association
    Standard Trauma and Resuscitation Course

    • Topic Presented: Head Trauma
  • April 6-9, 2006: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
    Pediatric Neurosurgery Training Course III Term - III Course, Malatya

    • Topics Presented:
      • Post-Traumatic Epilepsy / Carotid Cavernous Fistula
      • Cranial Tuberculosis Infections
  • May 15-18, 2006: National Trauma and Emergency Surgery Association
    Standard Trauma and Resuscitation Course

    • Topic Presented: Head Trauma
  • December 5-8, 2006: National Trauma and Emergency Surgery Association
    Standard Trauma and Resuscitation Course

    • Topic Presented: Head Trauma
  • April 5-8, 2007: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
    Pediatric Neurosurgery Training Course, Mersin

    • Topics Presented:
      • General Overview of Spinal and Cranial Dysraphism
      • Shunt Systems
  • April 20-24, 2007: Turkish Neurosurgery Association Scientific Congress, Antalya
    Panel: Advances in Cranial Neuroendoscopy

    • Speakers:
      • Prof. Dr. Yusuf Erşahin
      • Assoc. Prof. Dr. Ağahan Ünlü
      • Assoc. Prof. Dr. Suat Öktem
  • December 4-7, 2007: National Trauma and Emergency Surgery Association
    Standard Trauma and Resuscitation Course

    • Topic Presented: Head Trauma
  • May 25-27, 2007: 2nd Hydrocephalus Symposium, Izmir

    • Topic Presented: Treatment of Intraventricular Hemorrhage in Premature Infants
    • Panel: How Do I Place a Ventriculoperitoneal Shunt?
      • Assoc. Prof. Dr. Suat Öktem
      • Assoc. Prof. Dr. Çağatay Önal
      • Assoc. Prof. Dr. Ağahan Ünlü
      • April 3-6, 2008: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
        Pediatric Neurosurgery Training Course IV Term - I Course, Antalya
        Topic Presented:

        • Spinal Dysraphism and Neuroendoscopy Applications
      • May 7-10, 2008: 2nd National Trauma and Emergency Surgery Congress, Kayseri
        Panel: Current Approaches to Spinal Trauma

        • Assoc. Prof. Dr. Suat Öktem
        • Prof. Dr. Haluk Yalçınkaya
        • Assoc. Prof. Dr. Osman Akpinar
      • October 21-23, 2008: 8th National Neurosurgery Congress, Ankara
        Panel: Cranial and Spinal Tumors in Children

        • Prof. Dr. Recep Güloğlu
        • Prof. Dr. Savaş Aydar
        • Assoc. Prof. Dr. Suat Öktem
      • May 18-21, 2010: National Trauma and Emergency Surgery Association
        Trauma and Resuscitation Course
        Topic Presented:

        • Head Trauma and Neurosurgical Approaches
      • October 10-14, 2010: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
        Pediatric Neurosurgery Training Course, Antalya
        Topic Presented:

        • Spinal and Cranial Dysraphism and Current Approaches
      • November 23-26, 2011: National Trauma and Emergency Surgery Association
        Trauma and Resuscitation Course
        Topic Presented:

        • Spinal Trauma and Surgical Approaches
      • April 23-26, 2013: 4th National Pediatric Neurosurgery Congress, Kayseri
        Panel: Cranial and Spinal Tumors in Children

        • Prof. Dr. Recep Güloğlu
        • Assoc. Prof. Dr. Suat Öktem
      • December 4-7, 2013: National Trauma and Emergency Surgery Association
        Trauma and Resuscitation Course
        Topic Presented:

        • Cranial and Spinal Trauma
      • May 19-21, 2015: Turkish Neurosurgery Association / Pediatric Neurosurgery Group
        Pediatric Neurosurgery Training Course, Kayseri
        Topic Presented:

        • The Role of Neuroimaging in Pediatric Neurosurgery
      • April 27-30, 2017: National Pediatric Neurosurgery Congress, Antalya
        Panel: Advances in Cranial and Spinal Surgery

        • Prof. Dr. Yusuf Erşahin
        • Assoc. Prof. Dr. Suat Öktem
      • November 5-8, 2019: National Trauma and Emergency Surgery Association
        Advanced Trauma and Resuscitation Course
        Topic Presented:

        • Management of Multi-Trauma Patients
      • December 10-13, 2020: National Pediatric Neurosurgery Congress, Antalya
        Panel: Pediatric Cranial and Spinal Surgery

        • Assoc. Prof. Dr. Suat Öktem
        • Prof. Dr. Şahin Gürlek

      • II- Administrative and Scientific Activities

        A- Administrative Experience

        • 2005-Present: Head of the Neurosurgery Department, Erciyes University Faculty of Medicine
        • 2010-2015: Director, Kayseri Neurosurgery Education and Research Hospital
        • 2015-Present: Director, Pediatric Neurosurgery Training and Research Center, Erciyes University
        • 2019-Present: Chair, Neurosurgical Trauma and Emergency Care Committee, Turkish Neurosurgery Association

        B- Scientific and Academic Memberships

        • 1995-Present: Turkish Neurosurgery Association
        • 2001-Present: European Association of Neurosurgical Societies (EANS)
        • 2004-Present: World Federation of Neurosurgical Societies (WFNS)
        • 2010-Present: Pediatric Neurosurgery Group, Turkish Neurosurgery Association
        • 2015-Present: Scientific Committee Member, Turkish Trauma and Emergency Surgery Association

        C- Editorial Board Membership

        • 2010-Present: Editor, Turkish Journal of Neurosurgery
        • 2014-Present: Associate Editor, Journal of Pediatric Neurosurgery
        • 2016-Present: Editorial Board Member, Turkish Journal of Trauma and Emergency Surgery

        D- National and International Research Projects

        • 2005-2007: "The Role of Neuronavigation in Pediatric Neurosurgery," funded by the Scientific and Technological Research Council of Turkey (TÜBİTAK).
        • 2008-2010: "Spinal Dysraphism: Early Diagnosis and Surgical Techniques," funded by Erciyes University Research Fund.
        • 2013-2016: "Traumatic Brain Injury: Diagnostic and Therapeutic Approaches," supported by the Turkish Health Ministry.
        • 2017-2020: "Development of a New Hydrocephalus Treatment Protocol," collaborative research project with European Neurosurgical Cente
      • Asst. Prof. Dr. Adnan Dağçınar
      • Congress Organizing Committee

        Prof. Dr. Aydın Paşaoğlu Neurosurgery Days-I
        March 02-03, 2018, Kayseri

        Organizing Committee:
        Prof. Dr. Ali KURTSOY
        Prof. Dr. Ahmet SELÇUKLU
        Prof. Dr. İ. Suat ÖKTEM
        Prof. Dr. R. Kemal KOÇ
        Assoc. Prof. Dr. Abdulfettah TÜMTÜRK
        Assoc. Prof. Dr. Ahmet KÜÇÜK
        Asst. Prof. Dr. Halil ULUTABANCA

        Prof. Dr. Aydın Paşaoğlu Neurosurgery Days-II
        April 20, 2019, Kayseri

        Organizing Committee:
        Prof. Dr. Ali KURTSOY
        Prof. Dr. Ahmet SELÇUKLU
        Prof. Dr. İ. Suat ÖKTEM
        Prof. Dr. R. Kemal KOÇ
        Assoc. Prof. Dr. Abdulfettah TÜMTÜRK
        Assoc. Prof. Dr. Ahmet KÜÇÜK
        Asst. Prof. Dr. Halil ULUTABANCA

        Turkish Neurosurgery Association Scientific Congress
        September 30 - October 03, 2021, Belek, Antalya
        Congress Organizing Committee / Congress Secretary

        Turkish Neurosurgery Association Scientific Congress
        November 24-27, 2022, Belek, Antalya
        Congress Organizing Committee

        Turkish Neurosurgery Association Scientific Congress
        April 27-30, 2023, Belek, Antalya
        Congress Organizing Committee

        V- Theses Supervised

        A- Doctorate

        • Timing of ventriculoperitoneal shunt application in myelomeningocele
          Dr. Abdurrahman Özdemir, 2002, Kayseri
        • Comparison of intraoperative interventions in shunt infections and obstructions after ventriculoperitoneal shunt
          Ali Zantur, 2004, Kayseri
        • Ventriculoperitoneal shunt application in germinal matrix-originated post-hemorrhagic hydrocephalus in low birth weight premature infants
          Dr. Vaner Köksal, 2007, Kayseri
        • Effects of N-acetylcysteine, dextran, and saline combination on lipid peroxidation and brain edema in experimental traumatic brain injury in rats
          Yurdaer Doğu, 2009, Kayseri
        • The role of transcranial Doppler in preoperative and postoperative evaluation of craniosynostosis cases
          Resul Emin Börklü, 2014, Kayseri
        • Evaluation of the relationship between preoperative and postoperative platelet counts and blood transfusion amount in craniosynostosis cases
          N. Alper Durmuş, 2020, Kayseri

        Main Research Works

        Öktem İS, Akdemir H, Koç K, Menkü A, Tucer B, Selçuklu A, Turan C: Migration of abdominal catheter of ventriculoperitoneal shunt into the scrotum. Acta Neurochir 140:167-170, 1998

        Öktem İS, Akdemir H, Kurtsoy A, Koç RK, Menkü A: Hemilaminectomy for the removal of spinal lesions. Spinal Cord 38:92-96, 2000
        Akdemir H, Öktem İS, Tucer B, Menkü A, Başaslan K, Günaldı Ö: Intraoperative Microvascular Doppler Sonography in Aneurysm Surgery. Minim Invas Neurosurg 49:312-316, 2006
        Akdemir H, Öktem İS, Menkü A, Tucer B, Tuğcu B, Günaldı Ö: Image-Guided Microsurgical Management of Small Arteriovenous Malformation: Role of Neuronavigation and Intraoperative Doppler Sonography. Minim Invas Neurosurg 50:163-169, 2007
        Öktem İS, Menkü A, Özdemir A: When should ventriculoperitoneal shunt placement be performed in cases with myelomeningocele and hydrocephalus?. Turkish Neurosurg 18:387-91, 2008

        Other Official Activities
        President of the Administrative Board of Erciyes University Faculty of Medicine
        October 24, 2005 - September 10, 2008

        Administrative Roles
        Vice Chief Physician of Erciyes University Faculty of Medicine Hospitals
        August 24, 2004 - September 10, 2008

        Chair of the Neurosurgery Department at Erciyes University Faculty of Medicine
        2006-2009, 2014-2015, 2019-2024

        Faculty Council Member (Professor Representative), Erciyes University Faculty of Medicine
        2011-2014, 2014-2017

        Executive Board Member (Professor Representative), Erciyes University Faculty of Medicine
        2011-2014

        Speaker, Session Chair, or Attendee at Congresses, Conferences, Symposiums, Courses, and Other Scientific Meetings

        • 1996 Turkish Neurosurgery Association Scientific Congress
        • International Bakırköy Days
        • 1996 Post-Graduation First Aid and Emergency Course
        • 1997 Turkish Neurosurgery Association Scientific Congress
        • 1998 Turkish Neurosurgery Association Scientific Congress
        • 1998 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 1998 Turkish Neurosurgery Association Autumn Symposium
        • 1999 World Federation of Neurosurgical Societies Course
        • 2000 "Navigation Applications in Neurosurgery" Workshop, Erciyes University Faculty of Medicine Neurosurgery Department, Kayseri
        • 2001 World Federation of Neurosurgical Societies, Australasia
        • 2002 Erciyes University Faculty of Medicine/Post-Graduation Education Program
        • 2003 Erciyes University Faculty of Medicine/Post-Graduation Education Program
        • 2003 Hacettepe University Continuing Medical Education Events
        • 2003 Regional Trauma and Emergency Surgery Congress
        • 2003 Turkish Neurosurgery Association, Pediatric Neurosurgery Group, Three-Year II. Education Course (2nd time)
        • 2004 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2004 Erciyes University, Faculty of Medicine, Medical Education Department "Educational Skills Course," Kayseri
        • International Symposium on Microneurosurgical Anatomy
        • 2005 Turkish Neurosurgery Association Scientific Congress
        • 2005 National Neonatology Congress
        • 2005 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2005 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course, Course Director
        • 2005 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course I
        • 2005 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course II
        • 2006 Turkish Neurosurgery Association Scientific Congress
        • 2006 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2006 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course
        • 2006 Turkish Neurosurgery Association (Trauma and Intensive Care) Symposium
        • 2007 Turkish Neurosurgery Association Scientific Congress
        • 2007 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2007 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course
        • 2007 Hydrocephalus Symposium, İzmir
        • 2007 Gevher Nesibe Medical Days
        • 2008 Turkish Neurosurgery Association Scientific Congress
        • 2008 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2008 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course I
        • 2008 National Trauma and Emergency Surgery Association Trauma and Resuscitation Course II
        • 2009 Turkish Neurosurgery Association 23rd Scientific Congress
        • 2009 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2008 Turkish Neurosurgery Association Teaching and Education Summit
        • 2009 Nervous System Surgery Association Scientific Congress
        • 2009 Turkish Neurosurgery Association Teaching and Education Summit
        • 2010 Turkish Neurosurgery Association Scientific Congress
        • 2010 Turkish Neurosurgery Association / Pediatric Neurosurgery Group
        • 2010 Turkish Neurosurgery Association Stereotactic Workshop
        • 2010 Turkish Neurosurgery Association Teaching and Education Summit
        • 2010 Pediatric and Adolescent Neurology Spring Symposium
        • 2011 Turkish Neurosurgery Association Scientific Congress
        • 2011 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2012 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2013 Turkish Neurosurgery Association Scientific Congress
        • 2013 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2013 International Society for Pediatric Neurosurgery, Mainz – Germany
        • 2013 Traffic Safety Seminar
        • 2014 Turkish Neurosurgery Association Scientific Congress
        • 2014 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2015 Turkish Neurosurgery Association Scientific Congress
        • 2015 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2015 Turkish Neurosurgery Academy I. Meeting
        • 2015 International Society for Pediatric Neurosurgery, İzmir – Turkey
        • 2016 Turkish Neurosurgery Association Scientific Congress
        • 2016 Turkish Neurosurgery Academy 2nd Meeting
        • 2016 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2016 Turkish Neurosurgery Association Basic Neurosurgery Course
        • 2017 Turkish Neurosurgery Association Scientific Congress
        • 2017 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2017 Turkish Neurosurgery Academy 3rd Conference
        • 2017 Turkish Neurosurgery Association SPSCG Winter Meeting
        • 2017 Turkish Neurosurgery Association TURNOG Workshop
        • 2018 Turkish Neurosurgery Association Scientific Congress
        • 2018 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2018 Prof. Dr. Aydın Paşaoğlu Neurosurgery Days – I
        • 2018 Turkish Neurosurgery Academy 4th Conference
        • 2019 Turkish Neurosurgery Association Scientific Congress
        • 2019 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2019 Prof. Dr. Aydın Paşaoğlu Neurosurgery Days – II
        • 2019 Turkish Neurosurgery Academy Scientific Conference
        • 2020 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2022 Turkish Neurosurgery Association Scientific Congress
        • 2022 Turkish Neurosurgery Academy Academic Writing Education Course
        • 2023 Turkish Neurosurgery Association Scientific Congress
        • 2023 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course
        • 2024 Turkish Neurosurgery Association Scientific Congress
        • 2024 Turkish Neurosurgery Association / Pediatric Neurosurgery Education Course


IVF treatment, which is preferred by couples who cannot conceive naturally and cannot have children, is a source of hope for couples who cannot have children due to the development of medicine and technology. IVF treatment is the fertilization of male and female reproductive cells outside the body under laboratory conditions. Currently, couples have a 95 percent chance of success with IVF treatments. IVF treatment is one of the most successful methods in the treatment of infertility, the cause of which is not clear, or which cannot be conceived in the most natural ways. If couples do not succeed in their first attempts at IVF treatments, they should not despair and stress immediately. Because there are no restrictions on IVF treatment.

How many times can IVF treatment be tried?

 

A study conducted on couples undergoing IVF treatment shows that the rate of achieving pregnancy in couples after the first three trials is 95 percent. In addition, no number can be given about the number of treatments in the remaining group. The experts are also 4. or 5. there is an opinion that the chances of IVF success in trials are slightly lower than in the first three trials. The success rate of IVF treatment does not depend on many attempts. Multiple factors, such as the age of the couples, obtaining a quality embryo, affect the success rate of IVF treatment at a critical point.


Is Success Achieved in the First Attempt in IVF?

The chances of pregnancy during the one-month treatment period with the insemination method or ovulation treatments are about 20% or slightly more than the chances of a healthy couple becoming pregnant in a month. These treatments can be tried 3 or 4 times until pregnancy is achieved, but most of the pregnancies are obtained in the first months of treatment. Continuing treatment for more than 4 years will not increase the chances of pregnancy, so you can switch to IVF treatment.


Currently, thanks to newly developed methods and applications, the success rate of in vitro fertilization treatment is gradually increasing, if success is not achieved at the first attempt, repeated attempts can be made. The chance of becoming pregnant in a month with IVF treatments varies depending on age, but on average it is up to 50-60%. Pregnancy rates can increase by more than 90% after 4 applications when more than one treatment is performed in a row. For this reason, the chances of becoming pregnant increase with the number of attempts in couples who do not have a specific problem.


The application of Botulinum toxin (botox) to the stomach is a relatively new weight loss method based on the endoscopic injection of Botulinum toxin into certain parts of the stomach. Gastric botox, which provides "weight loss" without the need for surgical intervention, is the most preferred among the non-surgical slimming options.


Who is Stomach Botox suitable for?


Stomach botox can actually be applied to anyone who wants to lose weight. This procedure is not an obesity surgery. Our patients who meet the following criteria can choose it.

Our patients, who cannot lose weight properly with diet and sports,

Our patients with a body mass index below 40,

For our patients with stomach ulcers or gastritis, they can have stomach botox after the treatment process is completed.



Who can't be applied stomach botox?


Like every application, there are people who should not be treated with stomach botox. Stomach botox should not be applied to cancer patients, especially pregnant women, those who are undergoing cancer treatment, those who have had recent surgery and those who have gastrointestinal system diseases. Also; It is not recommended to apply stomach botox alone to people whose body mass index is above 35 kg/m2. Because it will not be appropriate to reduce the targeted weight only with stomach botox, combined treatments or bariatric surgery will be more suitable for these patients.


Non-surgical weight loss operation is one of the new obesity treatment methods applied to a certain region of the stomach with the endoscopic method. With non-surgical weight loss, the contraction of the stomach muscles is restricted, and the digestion and emptying time of the stomach is delayed, thus allowing patients to experience loss of appetite.






What is Stomach Botox?

Stomach botox is a relatively weight loss method and is an application based on the endoscopic injection of Botulinum toxin to certain parts of the stomach. By limiting the contraction of the stomach muscles, the gastric emptying time is delayed, the patient begins to lose appetite and thus the desired weight loss is achieved. The amount of weight lost varies according to the person's age, metabolic rate and supportive exercises. There is no history of the application in the literature, but it is not possible for those with muscle disease and allergy to botox to benefit from this application. Stomach botox has an appetite-reducing and diet-supporting effect, but it is not right to expect a miraculous effect. After gastric botox application, approximately 10-15 kilos can be easily lost by following the diet to be arranged by a professional dietitian and supporting it with sports.








How long does the stomach botox process take, is it necessary to stay in the hospital?


How long does the stomach botox process take, is it necessary to stay in the hospital?

Stomach botox is not an obesity surgery

It is a procedure that is completely endoscopically entered through the mouth.





There is no stomach incision.

During the procedure, patients are put to sleep accompanied by an anesthesiologist.

Hospitalization is not required.

A decrease in appetite and control in appetite control are achieved within about 3 days after stomach botox application.


As couples who want to become parents cannot become parents with natural methods, couples resort to some treatments. In vitro fertilization is the first treatment method. And IVF treatment is a very advanced and effective treatment method. Some applications in IVF treatment are important for the positive outcome of the treatment. Embryo glue application, which is one of the important application methods, is a very successful application. Embryo glue is one of the applications without any known risk. As a result of the studies, it was concluded that it did not increase the risk of miscarriage or pregnancy complications. Now we will provide you with detailed information about embryo glue. We wish you pleasant reading.

What is Embryo Adhesive?



Embryo glue, a method used in IVF treatments, is a kind of liquid embryo culture medium enriched with a substance called hyaluronan, in which embryos are left before transfer to the uterus of the expectant mother.

Hyaluronan is a natural carbohydrate found in all tissues in the body. The embryo needs an environment rich in carbohydrates, amino acids and protein in order to develop healthily inside. In addition, embryo glue is also called embryo glue because it reduces the ability of the embryo to move in the uterus.

How and Who Is Embryo Adhesive Used?



Embryo adhesive application is done as follows:

After the embryos are developed in the laboratory for 3-5 days, the most suitable one for embryo transfer is selected.

· The most suitable embryos selected for transfer are taken into the embryo glue.

· Embryos are kept in this environment for about 30 minutes.

· After standing, the embryos are taken from the culture dish and drawn into the catheter (a thin tube).

· The catheter is then passed through the cervix under ultrasound guidance and the embryos are transferred to the uterus.

In expectant mothers who have repeated in vitro fertilization failure using the embryo glue method,

It is used in couples who want to have children over the age of 35, when the quality of the embryo depending on the egg or sperm is not very good.

Is the Success Rate High in Embryo Bonding?



Embryo adhesive is one of the most frequently used applications for the last 10 years in order to increase the chance of success in IVF treatment. Experts were unsure about the effectiveness of embryo glue at first. However, in recent years, the effectiveness of embryo glue has been observed as a result of scientific research. Today, embryo glue is applied by various IVF centers. Hüma IVF Center is one of these centers.

The high concentration of hyaluronan concentrates the embryo glue similar to the tissue of the fluids in the womb, so that better mixing of these fluids minimizes the mobility of the embryo. In addition, hyaluronan acts as a bridge between the embryo and the inner wall of the uterus by binding to the inner wall of the uterus and the molecules on the surface of the embryo. In this way, it helps the embryo to attach to the uterus.

We aimed to give you information on this subject by considering the embryo glue method. We talked about how this method is applied and its success rate.

Parents who want to have children generally prefer the most common in vitro fertilization treatment. Before this treatment, both mother-to-be and father-to-be go through many tests. Father-to-be passed; The first of the tests to test for infertility or other problems is the sperm test, also known as the spermiogram test. What is the spermiogram test for the analysis of the sperm cell? How is spermiogram done? What do spermiogram test results mean? We will answer all these questions for you in detail below. We recommend that you continue reading our article to have detailed information about the sperm test.

 What is a test (spermiogram)?



Sperm test done to men; It is a test to determine sperm health, sperm count, and whether the sperm are moving correctly in the channels. As a result of the sperm test, if the sperm shape is normal and there is a sufficient number of sperm, it is concluded that your reproductive ability is high. However, in some cases, men may have low sperm count or the ability to reproduce despite having abnormal semen. That's why doctors order a second test for the accuracy of the results. If your results are normal in your first sperm test, you give the other test and if it is normal, these two normal tests show that you do not have an infertility problem. If there are different conditions, your doctor may order other tests.

If there is no semen or sperm as a result of the sperm test, this may indicate that your ducts are blocked. If this is the case, your doctor will plan different surgeries to open the channels.

Issues and Precautions to Consider While Giving Sperm Sample



There are important points to be considered before giving the sperm sample and while giving the sperm sample. Among the things to be considered before giving a sperm sample, we can count that "men should abstain from sexual intercourse for 3 days". Fasting for 3 to 5 days is sufficient. These numbers are important because if you fast for less than 3 days, the sperm count may be low as a result of the sperm test. For this reason, we can say that fasting between 3 and 5 days is sufficient. It is possible to list the issues to be considered while giving a sperm sample as follows;

 

· Storing the sample in a sterile environment: It is important to protect your sample from the outside environment for a healthy and accurate spermiogram test result. If a sterile environment is not provided, the test result may be inaccurate. Therefore, do not put your hands, especially sample containers, etc. It is important that you keep it as sterile as possible.

· Protecting the delivered sperm from heat: Another important point is to keep your sample away from extreme temperature changes after ejaculation. Because these extreme temperature changes negatively affect spermatozoa. Ideal temperatures for the sample cup should be between 20°C and 37°C.

· Sperm volume, amount: Volume is extremely important in the sperm test. Your sperm volume is expected to be at least 1.5 ml. The reason why you cannot reach the lower limit of 1.5 ml may be external discharge during ejaculation. It is important to be careful about this.

· Use of lubricating foreign substances during the sperm test: It is important not to use any lubricant during the sperm test because these substances seriously affect the sperm parameters. External factors with such an impact can lead to wrong conclusions.

How is the Sperm Test Done?



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



After the sperm test is given by the prospective fathers, it is examined in the laboratory environment. This examination takes approximately 1-2 hours and after the first hour, active results begin to be obtained. However, sometimes different situations can be encountered. For example, the test is given, but no sperm can be seen when looked at. In these cases, sperm are taken again and centrifuged. When faced with such a situation, the time may be extended. If there is no additional test to be done, the test results are immediately available in an average of 1-1.5 hours.

What Do Sperm Test Results Mean?



       





Sperm test results can be evaluated in many ways. Sperm analysis evaluates the sperm by analyzing it from various aspects. We can list these analyzes as follows:

· Sperm count and density:

Sperm count describes the number of sperm in 1 ml of semen. The World Health Organization advocates that a normal sperm count should be at least 15 million per ml or at least 39 million per sample. Having fewer sperm than these numbers indicates a low sperm count.

· Sperm morphology:

Non-abnormal sperm have a long tail and oval head. Morphology refers to the size and shape of the sperm a person has. Sperm that do not have a normal size or are weak in shape have difficulty reaching the egg and fertilization.

· Sperm motility:

The ability of sperm to move efficiently is one of the most important factors for fertilization.

· PH level of sperm:

When the pH level is too high or too low, it can affect the health of sperm and its ability to pass through the female reproductive tract.

Apart from these, sperm health is examined by looking at many factors such as semen volume, liquefaction, and seminal fructose levels while performing the sperm test. After examining all factors in detail, the results are examined and reported to the patient.

What is the Sperm Test Result of a Healthy Individual?



Low sperm count can have many different causes. The first reason is smoking addiction. Smoking addiction is one of the important factors that reduce the sperm count. In addition to smoking, alcohol and drug addiction also affect sperm count. Sperm count can also be adversely affected when there is a deficiency in hormones, depending on the clogged ducts.

Hormones are one of the important factors for reproduction on their own. Since the deficiency in reproductive hormones directly affects sperm production, it increases the possibility of encountering problems in reproduction. Apart from these, mistakes made by couples who want to have children also affect the sperm count. Using natural products unconsciously and continuing to use them uncontrollably, without knowing the limit, does harm to the person instead of providing benefits. Long-term treatment and drugs used during the treatment also affect the sperm count.

IMSI in Sperm Selection



The IMSI (Intracytoplasmic Morpholgically Selected Sperm Injection) method is the magnification and examination of even the smallest cells using special microscopes. In the past, in the microinjection procedures applied in IVF treatments, living sperm cells could be enlarged up to 400 times. However, with IMSI, sperm can now be enlarged between 6000 and 8000 times. It is possible to examine and detect in detail the disorders called "vacuoles" that indicate the intracellular structures of the sperm and their genetic damage.

The IMSI technique is an extremely useful method. Selected sperm injection; It allows advanced morphological analysis of sperm without damaging the living sperm cell. Sperm with the highest fertilization ability are selected and a high chance of fertilization between 20% and 40% can be obtained with the applied microinjection application.

Precautions to be Considered for Sperm Quality



Couples who want to have children should pay attention to egg and sperm health and be careful in this regard. There are many factors that affect sperm quality, such as those that affect egg quality. One of these factors is undoubtedly a healthy diet. A healthy diet is extremely important for every organ in the body, of course also in sperm health.

In addition, exercise is very important in making you more vigorous and increasing your body's stamina and activity. Regular exercise will make you recover in a short time and will positively affect both your mental and physical health. Alcohol and smoking are substances that affect reproductive cells and should be avoided. This is a proven fact as a result of research. If we gather all these under one title, we can say that one should take care of his own health. Nutrition, avoiding alcohol, smoking, exercising regularly will first affect your health and therefore your sperm quality.

This process, which is sensitive and special for couples who want to have a child, is extremely important for them. In this process, prospective parents experience excitement on the one hand and a lot of stress on the other. Hüma IVF Center, which understands the emotions experienced best and does not spare its support by being by their side throughout the process, is always ready to accompany you.

Recently, it has been revealed that egg quality obtained from patients with low reserve is lower and genetic problems in the embryo are higher. In this direction, it is aimed to create fewer but better quality embryos by obtaining higher quality eggs with less drugs. Mini IVF appears as a simplified in vitro fertilization practice, unlike the known in vitro fertilization practices performed with daily injections and high-dose drug use. Especially in patients with a low number of eggs or in advanced age, the success rates are higher than conventional treatments. What is mini IVF, who is it applied to and what are the drugs used in its treatment? You can continue reading our article for questions and all the details.


What is mini IVF?



Mini IVF is an in vitro fertilization application that enables the development of fewer but higher quality eggs by using lower doses of drugs. Eggs developed with this method are taken and fertilization is performed by applying the microinjection technique. Embryos formed after fertilization are transferred to the patient, assuming that the probability of attachment is higher.

In addition to the advantages such as less drug use, less cost and less time spent with mini IVF treatment, high success rates can be obtained in patients with a low number of eggs and advancing age.



Who is mini IVF applied to?



In cases where pregnancy does not occur naturally;

Those who want to use hormone drugs less,

At risk of developing OHSS (overstimulation of the ovaries),

Concerned about the daily injection process in IVF treatment,

Those who have problems in the fallopian tubes and are younger than 35 years old,

Having low egg reserve that cannot be increased with treatment,

Looking for a more economical solution than conventional treatment,

People who have tried many times in vitro fertilization but have not achieved a result, and

Mini IVF treatment can be applied to women who want to reduce the possibility of multiple pregnancy.

However, a treatment plan should be made by a specialist by listening to the patient's history of the disease, analyzing their expectations and performing health checks in detail.



What are the drugs used in mini IVF treatment?



Mini IVF treatment is a type of in vitro fertilization that uses little or no medication to increase and develop the number of eggs. In standard IVF treatments, hormone injections are made for 8-10 days to reproduce eggs, while these drugs are not used in the Mini IVF method. Oral tablets and very low dose hormone injections are used instead. With Mini IVF, which is a natural in vitro fertilization method, it is ensured that the highest quality eggs are produced by using the least amount of medication.

Mini IVF method is aimed to obtain better quality eggs with the use of low doses of drugs. At this point, it is possible to determine your treatment plan by consulting your doctor. You can visit our website for more information.

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Calcium ionophore therapy is a treatment method applied to ensure a healthy fertilization and to obtain a high pregnancy rate. In order to talk about a healthy fertilization, when the sperm enters the egg, the enzyme in the head part of the egg must be released into the egg and the amount of calcium inside must increase.

If the amount of folfolipase C in the sperm is low, the egg cannot be fertilized because without phospholipase, the calcium rate in the egg does not increase.

Calcium ionophore therapy is an application that increases the amount of calcium in the egg. In the calcium ionophore application, the egg and sperm are first fertilized by micro-injection. After this process, the eggs are kept in a calcium ionophore for a few minutes. The main purpose here is to increase the calcium level that needs to be increased in the egg. In other words, calcium ionophore therapy helps the fertilization of the egg by supporting the reactions that should start in the egg. So, what is calcium ionophore therapy and to whom is it applied? Now we will answer all these questions for you.



What is Calcium Ionophore? To Whom Is It Applied?

It is possible to define calcium ionophore therapy as an application that increases the amount of calcium in the egg. This treatment method is generally applied to the people we will list below. Those people;

Individuals with successive fertilization problems

If very few eggs or sperm are obtained

In cases where no fertilization can be achieved with micro-injection therapy

In patients with “globosperm” of all sperms

Calcium ionophore therapy is applied.



Who Is Fertilized With Calcium Ionophore?

In cases where embryo transfer cannot be performed due to the fertilization step not taking place during IVF treatment, activation of the eggs and fertilization are aimed by using calcium ionophore. Thus, calcium ionophore therapy is applied. With this treatment method, the problem of non-fertilization can be eliminated and treatment can be applied in couples who have non-fertilization problems. This treatment method is also applied to couples who have problems as a result of obtaining a very small amount of egg and sperm. Fertilization is performed with the calcium ionophore treatment method and a high pregnancy rate is obtained.

In this article, we have given the answers to all these questions for you, what is calcium ionophore therapy, to whom this treatment method is applied and in whom fertilization occurs as a result of the treatment.

It may interest you: What is infertility, what are its symptoms, what kind of treatment method is applied?

IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.



What is Comprehensive Chromosome Screening (NGS)?


It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.

Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.


What are the Features of the NGS Technique?




Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.


What Genetic Defects Can Be Detected with NGS-Based PGS?



Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.

To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.


Who are the Groups of Patients Who Can Be Administered NGS?




The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;

· In cases of repeated miscarriage,

· in expectant mothers over the age of 38,

· In severe male infertility,

* In cases of infertility, the cause of which is unknown,

· It is applied in cycles of continuous self-recurring treatment failures.

The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.


What are the Advantages of Preimplantastone Genetic Screening with NGS?




NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.


Does NGS Damage the Embryo?




IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.


Does Pregnancy Always Occur With a Smoothly Detected Embryo?




After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;

· Women's age

· The amount of ovarian reserve of the woman

* Sperm quality

· Embryo quality

· Ensuring a proper intrauterine environment

· The presence of hydrosalpinx

· Conditions encountered during embryo transfer

it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.

Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.

In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.


How Many Days Do NGS Results Come Out?



The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.

What are the NGS Test Prices?

The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.

In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.

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