Last Update Date
24.03.2025

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Especially in Gynecological and Oncological Surgery Op. Dr. Under the leadership of Erşad Batmaz, successful operations in female gynecological cancers, especially Wertheim (Radical Hysterectomy) Operations and Lymph Dissection, are performed in our hospital.

Surgery for gynecologic cancer typically involves removal of the tumor, and may include removal of the:
  • Cervix
  • Uterus
  • Ovaries
  • Other pelvic organs
Hüma Hospital, offers the latest surgical treatment options for gynecologic cancers.

Our expert surgeons will:
Evaluate the size and location of your tumor.
Attempt to remove as much of the tumor as possible. Reducing the size of the tumor improves the efficiency of subsequent chemotherapy and radiation therapy, since there is less tumor to treat.
Guide you to the appropriate surgical procedure for your type of gynecologic cancer.

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Every woman wants to feel the maternity. We try to see smiling on your face for that very small breath to be included into your world. We, as Huma IVF Center, plan to be with you in this process from the first step of your treatment to your birth with awareness of your infertility problems. We target to bring you together with the healthy individuals in your home while starting with the slogan ‘Let us Add Your Imagination into Your Life’, believe that you will feel safe and in peace in our center. We take the fair pride in presenting the high quality service to you with a principle trying to catch the world standards with our knowledge.


WHY IS HUMA IVF CENTER?
Our success in the assisted reproductive treatments is based on a team working in plan and in coordination.
Our team consisted of the gynaecologists, embryologists, nurses and the patient consultants expert at their subjects, open to share information shall be glad to give service to you in this way where you started in order to be able to have a child.
Huma IVF Center started out by making renewing itself every passing day in the infertility practices a rule. We are over the world standards at rates of pregnancy to be obtained by using the assisted reproductive techniques.
Our patient consultants are in your service in all stages of your treatments in order to ease the IVF center treatment processes of our patients who will come to our center for treatment from abroad. We enable accommodation at a discount in our contractual hotels and the transportation support, prepare the programs where you will be able to follow your treatment at a distance.

IVF Center Treatment Techniques

• TESE- TESA Practices
• PGT (Pre-implantation Genetic Diagnostic)
• Calcium Ionophore
• Intra lipid
• Asisted Hatching
• Microchip
• Embryoscopy
• Pool Method
• Uterus Resting
• PRP

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PREIMPLANTATION GENETIC DIAGNOSIS
In recent years, developments in genetics allow genetic analysis to be carried out on embryos developed in vitro by in vitro fertilization  ethods and the placement of selected healthy embryos in the uterus of the mother before pregnancy occurs. This method is called pre- regnancy genetic diagnosis (Preimplantation Genetic Diagnosis-PGD).
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One of the most important application areas of the PGT technique embryos that do not have a genetic disease but may not have a genetic disorder in their chromosomes.
These disorders are more common in women of advanced age (35 years and older). This situation may result in infertility as it both reduces the chance of attachment of the embryo (implantation) and may cause unwanted abortions. As a matter of fact, 40 out of every 100 pregnancies in women aged 39 and over have problems that occur due to a numerical chromosomal disorder
 
The aim of PGD is to increase implantation rates, reduce spontaneous abortions and increase healthy baby birth rates by selecting hromosomally normal embryos. Indeed, the miscarriage rate, which can reach up to 23 percent in normal pregnancy due to chromosomal disorders, may decrease to 9 percent after PGD.
 
Pre-pregnancy genetic diagnosis is performed by taking 1 or 2 cells from embryos developed as a result of fertilization of egg and sperm cells obtained from mother and father candidates in laboratory environment. Special methods called Fluorescence In Situ Hybridization (FISH), Microarray-based comparative genomic hybridization (aCGH) or Polymerase Chain Reaction (PCR) are used for genetic diagnosis. Diagnosis of numerical chromosomal disorders such as monosomy or trisomy (Down syndrome and other trisomies) and single gene diseases (such as hemophilia, Mediterranean anemia, cystic fibrosis, muscular dystrophies) in the baby to be born is possible with PGD. Thus, healthy babies are born by transferring disease-free, healthy embryos to the expectant mother.
 
DIAGNOSIS BEFORE PREGNANCY
 
  • In couples with a genetic or hereditary disease carrier,
  • In couples who have a child or children with a previous genetic disease,
  • For the purpose of HLA genotyping (tissue typing),
  • In the identification of diseases showing genetic predisposition (tendency)
  • Women in the advanced age group (37 years and over) who have been accepted for assisted reproductive techniques,
  • In couples with recurrent early pregnancy miscarriages,
  • In couples who could not achieve pregnancy with assisted reproductive techniques despite multiple applications or who lost their pregnancy due to miscarriage,
  • It is applied in cases of chromosomal disorders or genetic diseases associated with severe male infertility.
 
HOW IS THE PGT TEST DONE?
 
  • Whether the patient is suitable for PGD is evaluated by the reproductive health specialist, genetic counselor and the doctor of the related disease.
  • The couple is prepared for the IVF procedure.
  • The egg taken from the mother is fertilized in the laboratory with the sperm taken from the father.
  • 1-2 blastomere cells are removed from the obtained embryo by biopsy by embryologists
  • Cells obtained by biopsy are prepared and tested according to the method to be applied.
  • Embryos with genetic diseases or chromosomal disorders are selected and discarded and healthy embryos are transferred to the mothers womb.

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It is a technique developed to increase the rate of attachment of embryos to the uterus. In this technique, puncture the sheath (zona pellucida) surrounding the embryo by laser, acid or mechanical methods opens. This process can also be used prior to the transfer of cryopreserved embryos. 

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In patients with low sperm viability, quantity, number and structural quality, microfluidic technology, also known as the "chip baby method", ensures that the best quality sperm cells are selected by competing with each other in a way similar to the natural environment in the uterus, and ICSI is defined in in vitro fertilization treatment. With the application, it is left into the egg cell by microinjection method.

In this method, sperm cells with the best structural form, genetics and physiology are selected without causing cell damage, since techniques such as centrifugation (settling), vortex (mixing with high vibration) or mixing with a pipette are not applied to the sperm cells, which can physically damage the sperm cells. In classical preparation methods, sperm cells are prepared in a shorter time without being subjected to manipulation by skipping processes such as washing, flotation, gradient (grading), centrifugation (precipitation at high speeds). Thus, the sperm cells with the best DNA quality and physiologically are selected by themselves, and the sperm cells that pass this pre-screening are again screened under the microscope and the sperm cells of excellent quality are used for microinjection.

The above-mentioned classical preparation methods cause sperm cells to undergo respiratory stress, known as oxidative stress, and it has been scientifically proven that this can also cause DNA damage in healthy sperm cells. Better quality embryos are tried to be obtained with sperm cells that have been proven to be of the best quality by scientific data, and thus embryos with the highest potential for implantation (attachment) and development are obtained. The average total mobility in suckling samples taken from male individuals with microchip technology increased by 1.7 times.
The sperm cells obtained by this method were found 3 times faster than the classical preparation methods, and the forward motile sperm cells increased 3.8 times.

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MD. ERSAD BATMAZ, has graduated from GATA Military Medical Faculty. He completed his specialty training at GATA Haydarpaşa Training Hospital. He started to work as a Gynecology and Obstetrics specialist in Erzincan Military Hospital in 1990. After 3 years of duty at Erzincan Military Hospital, he served in Kayseri Military Hospital and Ankara Mevki Military Hospital.

Ersad Batmaz, who served as the Head Physician in Kayseri Maternity Hospital in 2002, established Private Hüma Hospital, which is the first and only Gynecology and Maternity Hospital in Kayseri, in 2004.

 

Since 2004, he has been working as the Chairman of the Board of Directors and Obstetrics and Gynecology Specialist at Hüma Hospital with 31 years of experience as a physician.

In addition to his successful operations in gynecological and oncological surgery, he has performed 8.195 surgeries and 7.168 deliveries so far. Successful operations in female gynecological cancers, especially Wertheim (Radical Hysterectomy) Operations and Lymph Dissection, are in the first place.

In addition to this, laparoscopic surgeries, Vaginal Hysterectomy, surgery to repair structural defects of the uterus, removal of intrauterine polyps and fibroids, diagnostic laparoscopy for infertility diagnosis and treatment, hysteroscopic operations, endometriosis surgeries, ovarian cysts operations, postpartum vaginal incontinence operations.  With its success, it is often mentioned

All the operations performed by MD. Ersad Batmaz
GYNECOLOGICAL OPERATIONS;
• Wertheim (Radical Hysterectomy) Operations
• Abdominal Hysterectomy
• Vaginal Hysterectomy
• Laparoscopic Hysterectomy
• Ovarian cyst operations
• TAH BSO
• Vaginal cuff prolapse repair
• Myomectomy
UROGINECOLOGICAL OPERATIONS;
• Rectocele
• Cystocele (Urinary Incontinence)
• Rectosystocele
• Operation Marshall- Marcetti Kranz
CLOSED SURGERY
• Laparoscopic surgeries
• Laparoscopic myoma removal
• Laporoscopic Removal of Ovarian Cysts
• Laparoscopic Endometriosis surgeries
• Diagnostic laparoscopy for infertility diagnosis and treatments
HYSTEROSCOPIC SURGERIES
• Surgery for Repairing Structural Disorders of the Uterus
• Surgery to remove intrauterine polps, myomas
GENITAL AESTHETIC OPERATIONS
• Perinoplasty
• Labiaplasty
• Enlargement of Vaginal Stenosis
OBSTETRIC OPERATIONS
• Normal birth 
• Birth in water
• Cesarian section

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EDUCATION

  • Medical Education: Erciyes University Faculty of Medicine
  • Specialization: Erciyes University Faculty of Medicine, Pediatric Surgery
  • Associate Professorship: Harran University Faculty of Medicine

WORK EXPERIENCE

  • Niğde State Hospital: 1998-2006
  • Erciyes University Faculty of Medicine: 2006-2011
  • Balıklıgöl State Hospital (Şanlıurfa): 2011-2013
  • Harran University Faculty of Medicine: 2013-2022
  • SBÜ Kayseri City Hospital: 2022-2024
  • Private Hüma Hospital: 2024-Present

AREAS OF INTEREST

General Pediatric Surgery

  • Congenital diaphragmatic hernias
  • Intestinal atresias
  • Gastroesophageal reflux
  • Esophageal pathologies (esophageal atresia, achalasia)
  • Pyloric stenosis
  • Abdominal wall defects (omphalocele, gastroschisis)
  • Inguinal pathologies (hydrocele, inguinal hernia)
  • Intussusception
  • Intra-abdominal masses (Wilms tumor, neuroblastoma, hepatoblastoma)
  • Sacrococcygeal teratomas
  • Ovarian pathologies
  • Biliary atresias
  • Biliary tract diseases

Pediatric Urology

  • Congenital uropathies
  • Ureteropelvic junction obstruction
  • Ureterovesical junction obstruction
  • Vesicoureteral reflux
  • Undescended testis
  • Bladder exstrophy and epispadias complex
  • Hypospadias
  • Urinary incontinence
  • Nocturnal enuresis

MEMBERSHIPS

  • TTB - Turkish Medical Association
  • PEDURO - Pediatric Urology Association
  • TÇCD - Turkish Pediatric Surgery Association
  • Kayseri Medical Chamber

CERTIFICATIONS

Abnormalities Diagnosed During Pregnancy:

(Including issues related to the respiratory system, kidneys, bladder, diaphragmatic hernia, abdominal wall anomalies, esophageal/bowel atresias, and some congenital tumors)

Congenital Anomalies Detected in the Neonatal Period (0-28 days):

  • Respiratory system and lung anomalies
  • Esophageal anomalies
  • Stomach and intestinal system anomalies
  • Liver and biliary tract anomalies
  • Kidney, urinary tract, and bladder anomalies
  • Abdominal wall formation anomalies
  • Congenital tumors

Issues Detected During Infancy (2-24 months):

  • Congenital anomalies (respiratory system, gastrointestinal system, reproductive and urinary tracts)
  • Intestinal bleeding
  • Intussusception (telescoping of the intestines)
  • Meckel's diverticulum
  • Pyloric stenosis (narrowing of the stomach outlet)
  • Bile duct obstructions

Common Issues Encountered at All Ages:

Surgical Problems:

  • Inguinal hernia
  • Hydrocele
  • Undescended testis (cryptorchidism)
  • Umbilical hernia
  • Appendicitis
  • Intestinal obstructions
  • Foreign objects in the respiratory or gastrointestinal system
  • Constipation, anal fissures
  • Recurrent urinary tract infections
  • Issues with fecal and urinary incontinence (encopresis, enuresis)

ISSUES RELATED TO THE ESOPHAGUS

  • Stomach reflux (gastroesophageal reflux)
  • Esophageal burns and strictures (corrosive esophagitis)
  • Swallowing difficulties (esophageal web, achalasia)

ISSUES RELATED TO THE GASTROINTESTINAL SYSTEM

  • Stomach outlet obstructions (infantile hypertrophic pyloric stenosis)
  • Small and large intestine obstructions (intestinal obstruction)
  • Hirschsprung disease (congenital aganglionic megacolon)
  • Absence of the anus (anal atresia)

ISSUES RELATED TO THE LIVER AND BILIARY TRACTS

  • Liver cysts (simple cysts, hydatid cysts)
  • Congenital bile duct abnormalities (choledochal cyst)
  • Pancreatic abnormalities
  • Gallstones (cholelithiasis)

ISSUES RELATED TO THE KIDNEYS AND URINARY TRACTS

  • Kidney outlet obstruction (ureteropelvic junction obstruction, UPJ)
  • Kidney reflux (vesicoureteral reflux, VUR)
  • Narrowing of the urinary tract (ureterovesical junction obstruction, posterior urethral valve)
  • Stone disease (urolithiasis, nephrolithiasis)
  • Improper placement of the urinary opening (hypospadias, epispadias)
  • Absence of the bladder front wall (bladder exstrophy)
  • Disorders of sexual differentiation (ambiguous genitalia, intersex conditions)

ISSUES SPECIFIC TO GIRLS

  • Ovarian cysts and ovarian torsion
  • Absence or obstruction of the uterus or vagina
  • Closed hymen (imperforate hymen)
  • Adhesions in external genitalia (labial synechiae, labial fusion)

CHILDHOOD CANCERS

  • Kidney and adrenal gland tumors (Wilms tumor, neuroblastoma)
  • Liver tumors (hepatoblastoma, hepatocellular carcinoma)
  • Lymph node tumors (leukemia and lymphomas)
  • Muscle tissue tumors (rhabdomyosarcoma), soft tissue tumors
  • Endocrine gland tumors (thyroid, pancreas, adrenal gland surgical conditions)
  • Tumors of the testes (in boys) and ovaries (in girls)
  • Issues related to the blood vessels and lymphatic system (hemangiomas and lymphangiomas)

OTHER ISSUES

  • Neck curvature (torticollis)
  • Ingestion of foreign objects (foreign bodies in the esophagus, stomach, or intestines)
  • Aspiration of foreign objects into the airway (foreign bodies in the trachea or bronchi)
  • Chest wall depression (funnel chest, pectus excavatum)
  • Chest wall protrusion (pigeon chest, pectus carinatum)
  • Falls
  • Accidents
  • Blunt or penetrating trauma

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In some cases, it is not enough if only the reproductive system is healthy for pregnancy to occur. Along with the reproductive system, it is extremely important for the pregnancy process that many factors work in harmony with each other. Depending on the factors that affect the process, pregnancy may not occur in people. This condition can also be observed if the person has already become pregnant or had a healthy birth.
Infertility, which occurs as a result of a couple having regular sexual intercourse for 12 months and not being able to get pregnant even though they are not using a method of protection, can be seen in two different ways. Never before pregnancy occurs when primary infertility; a live birth or not, regardless of if at least one pregnancy occurred, secondary (secondary) infertility is defined as.
You can continue reading our article about what is secondary infertility, what are its causes, important risk factors and treatment topics.

Causes of Secondary Infertility


Secondary infertility can occur due to both of the couples. The causes of secondary male infertility; the presence of varicose veins in sperm vessels, known as varicocele, infections, traumas and testicular tumors can be listed in the form of. The causes of secondary infertility in women are causes such as differences in ovulation patterns, damage or blockage of the tubes, deterioration of the structure of the uterus, and cervical and cervical cancer, especially as age progresses.
Autoimmune diseases and sexually transmitted diseases are also among the causes dec lead to secondary infertility.
In order to determine which of the many factors considered to cause the development of secondary infertility in people and to make appropriate planning, the couple should consult a specialist physician.

Risk Factors for Secondary Infertility



One of the most curious points about secondary infertility is the risk factors of secondary infertility. Many risk factors can cause the development of secondary infertility in people. These factors;
• Progression of age
• Different disorders such as polycystic ovary syndrome
* Excess weight
• Previous miscarriages
* Stress
* Alcohol, smoking and substance use
It can be sorted as follows. Along with all this, various factors that may differ from person to person can also lead to the development of secondary infertility in people.

Treatment of Secondary Infertility



The causes of secondary infertility, which are an obstacle to a person's conception, can be studied in an extremely wide range. For this reason, first of all, the points that prevent a person from becoming pregnant should be determined by taking into account different factors and an appropriate treatment plan should be developed accordingly. As a result of the evaluations made by taking the patient's history, vaccination and IVF treatments may be recommended to support conception. In order to determine the condition, specific infertility tests can be administered to people after a physical and pelvic examination. The ovulation test and other hormone tests are some of them.
As Huma IVF center, we continue to be with you in this process with our expert staff. For all the questions you have in mind, you can contact us by checking out our experts on our website.

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IVF treatment; It is the method that offers the highest chance of pregnancy for couples who want to have a baby but cannot conceive naturally. In vitro fertilization method can be applied as a result of unprotected intercourse for more than 1 year, when pregnancy does not occur. Although it is a successful method, it may not always be possible to achieve 100% success in IVF treatments. There are many factors that determine the probability of successful IVF treatment. 


What Factors Depends on Success in IVF Treatment?

In IVF treatment, it is aimed to catch pregnancy in the first time, but pregnancy is not possible for every woman at once. Factors affecting the success of IVF treatment include the age of the expectant mother, weight status, problems in the uterus, hydrosalpinx in the tubes, immune system problems, smoking degree, alcohol use rate, and decreased ovarian reserve. With this; Various male-related conditions such as sperm immobility, severe deformities, and absence of sperm in the semen also affect the success rate of IVF treatment. General statistical data can give you information about the success rate in IVF treatment, but it should not be forgotten that every couple is very special and unique. In IVF treatment, your doctor can better determine your individual chances, taking into account your personalized factors. 


What are the Risks of IVF Treatment?





As with any treatment, there are some risks in IVF treatment. However, some of these risks, which are likely to be encountered in IVF treatment, are predictable and can be intervened early, although these risks are very rare. We can list these risks as follows: Mild bruising, swelling and pain may occur in the areas where the drugs were injected. Overstimulation of the eggs can result in weight gain, nausea, vomiting and bloating. There may be a risk of ectopic pregnancy. Bleeding may occur during egg collection.


What Should Be Done After Unsuccessful IVF?



 Failure of one or more IVF attempts can be extremely challenging, disappointing couples. This situation is extremely natural. One of the most important reasons for a failed IVF treatment is poor embryo quality. Defective and damaged embryos cannot be attached to the uterus after they are transferred to the uterus. However, in some cases, pregnancy may not be achieved despite transferring good quality embryos. Your doctor will evaluate the reasons for the failure of your IVF process in detail to determine what the problem is. These points will be taken into account in future attempts after the problem is determined. Taking a break for at least a month after a failed IVF attempt will also be very beneficial for the process. As developments in the field of medicine increase, it becomes easier to detect and eliminate negative situations. It is important that couples who fail their first IVF attempt should not despair. When conditions are improved, the chances of pregnancy will be higher in subsequent attempts.

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There are 2 treatment methods most commonly preferred by couples who want to have a baby but do not have a baby for various reasons. One of them is in vitro fertilization treatment and the other is insemination method. In our article, we will try to answer the most frequently asked questions about the vaccination method, what is insemination and how it is done.


What is insemination? 


If couples cannot get a pregnancy result after one year after unprotected sexual intercourse, infertility is diagnosed. Infertility can have many causes, depending on the woman and the man. Thanks to science and developing technology, there are now many treatment methods for infertility. One of these methods is the vaccination method. In its simplest form, the method of vaccination is to prepare the sperm in the laboratory and inoculate the woman's uterus at the time of ovulation to ensure fertilization. In order for the vaccination method to be performed, some tests must be done to make sure that there is no problem in the uterus of the expectant mother. In addition, at least one of the tubes of the expectant mother must be in working condition. The purpose of the vaccination method is to select the motile, normal sperm with a higher probability of fertilization and send them to the uterus of the expectant mother. Thus, it will be more likely to be fertilized with eggs and selected sperm supported by drugs or pills. 


How is insemination done?


Before the insemination method, the development of the egg is supported with pills or low-dose injections given to the expectant mother. During this process, the egg is tracked. When the eggs mature and reach certain sizes, a cracking needle is given and the eggs are cracked. Just at this time of cracking, the sperm prepared in the laboratory are transferred to the uterus. Thus, the most suitable time of ovulation is provided for the woman and the best sperm are transferred to the uterus at the right time. insemination is a natural method. Only sperms that will increase the probability of fertilization are carefully selected. From the sperms taken from the father-to-be, those that are of good quality, motile and washed in a certain number, that is, processed. As Hüma IVF Center team, we tried to give information about what is insemination and how it is done in our article. We hope it was useful. You can contact us via our website to get more detailed information about IVF treatment or to ask your questions.

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As couples who want to become parents cannot become parents with natural methods, couples resort to some treatments. In vitro fertilization is the first treatment method. And IVF treatment is a very advanced and effective treatment method. Some applications in IVF treatment are important for the positive outcome of the treatment. Embryo glue application, which is one of the important application methods, is a very successful application. Embryo glue is one of the applications without any known risk. As a result of the studies, it was concluded that it did not increase the risk of miscarriage or pregnancy complications. Now we will provide you with detailed information about embryo glue. We wish you pleasant reading.

What is Embryo Adhesive?



Embryo glue, a method used in IVF treatments, is a kind of liquid embryo culture medium enriched with a substance called hyaluronan, in which embryos are left before transfer to the uterus of the expectant mother.

Hyaluronan is a natural carbohydrate found in all tissues in the body. The embryo needs an environment rich in carbohydrates, amino acids and protein in order to develop healthily inside. In addition, embryo glue is also called embryo glue because it reduces the ability of the embryo to move in the uterus.

How and Who Is Embryo Adhesive Used?



Embryo adhesive application is done as follows:

After the embryos are developed in the laboratory for 3-5 days, the most suitable one for embryo transfer is selected.

· The most suitable embryos selected for transfer are taken into the embryo glue.

· Embryos are kept in this environment for about 30 minutes.

· After standing, the embryos are taken from the culture dish and drawn into the catheter (a thin tube).

· The catheter is then passed through the cervix under ultrasound guidance and the embryos are transferred to the uterus.

In expectant mothers who have repeated in vitro fertilization failure using the embryo glue method,

It is used in couples who want to have children over the age of 35, when the quality of the embryo depending on the egg or sperm is not very good.

Is the Success Rate High in Embryo Bonding?



Embryo adhesive is one of the most frequently used applications for the last 10 years in order to increase the chance of success in IVF treatment. Experts were unsure about the effectiveness of embryo glue at first. However, in recent years, the effectiveness of embryo glue has been observed as a result of scientific research. Today, embryo glue is applied by various IVF centers. Hüma IVF Center is one of these centers.

The high concentration of hyaluronan concentrates the embryo glue similar to the tissue of the fluids in the womb, so that better mixing of these fluids minimizes the mobility of the embryo. In addition, hyaluronan acts as a bridge between the embryo and the inner wall of the uterus by binding to the inner wall of the uterus and the molecules on the surface of the embryo. In this way, it helps the embryo to attach to the uterus.

We aimed to give you information on this subject by considering the embryo glue method. We talked about how this method is applied and its success rate.

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IVF treatment, which is one of the methods of treatment that helps reproduction, begins with the collection of eggs from the expectant mother and the removal of sperm cells from the expectant father. The embryo, which appeared after the fertilization was carried out in the laboratory environment, is placed in the womb of the expectant mother. From this point on, pregnancy continues like a pregnancy acquired by natural means.







When should couples who cannot have children turn to IVF treatment?



A woman under the age of 35 who does not have any diseases that can prevent her from becoming pregnant should definitely be examined if she cannot conceive despite having unprotected and regular sexual intercourse for 1 year and seek treatment if deemed necessary. Women who are over the age of 35 or who have previously had any problems affecting conception should only try for 6 months.







How is IVF Performed? What are the Necessary Conditions?



In vitro fertilization can be defined as the process of placing the healthiest embryo in the womb obtained as a result of fertilization of eggs collected from the expectant mother with the sperm of the expectant father in the laboratory environment. Before starting IVF treatment, the reproductive abilities of both a man and a woman are evaluated. Then hormone therapy is started to allow the expectant mother's eggs to enter the maturation process. Then, a cracking needle is made and the eggs are released from the follicles. During the egg collection process, the ripening eggs of the expectant mother are collected with the help of transvaginal ultrasound. At this time, sperm cells are taken from the expectant father. 









Fertilization is achieved by means of reproductive cells that are brought together in a laboratory environment dec The healthiest of the embryos that occur, or in other words, the best IVF, is transferred to the expectant mother's uterus accompanied by ultrasound. After about half an hour after this procedure, the couple is sent home. In some cases, more than one embryo needs to be transferred to the mother's womb.

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Adenomyosis is a female disease that occurs in women, especially as age increases. Women with adenomyosis experience extremely painful, painful and excessive bleeding menstrual periods. This heavy menstrual period also affects the daily life of women with adenomyosis. In addition, it causes anemia. If you are experiencing these problems and want to know more about Adenomyosis, you can continue reading our article.

What is Adenomyosis?



The uterus contains an inner lining of the uterus called the endometrium. The task of this inner membrane is to limit the inner surface of the uterus. The inner membrane inside the uterus is renewed every month with the menstrual period and in some women it moves towards the uterine muscle layer. Adenomyosis occurs as a result of thickening of the inner membrane in the uterine muscle layer.

There are two types of adenomyosis: benign and malignant. It is a benign type that is usually seen in women, but some women may also have a malignant type that requires surgery and poses a risk.

Women with adenomyosis have difficult days during their menstrual periods. During this period, they may have to cope with excessive pain and excessive bleeding. Again, they may feel uncomfortable bloating before the menstrual period and may experience pain and pain during sexual intercourse.

What are the Causes of Adenomyosis?



Although the causes of adenomyosis disease in women are not known clearly, it is known that hormones such as estrogen, prolactin, and progesterone trigger this ailment. Apart from this, external interventions in cesarean deliveries, surgical cuts or inflammation of the inner lining of the uterus during birth trigger the cells that regulate the uterus to leave their borders and cause adenomyosis. Development-related adenomyosis can also be seen. During the developmental process, the endometrial accumulation formed between the muscles during the first formation of the fetus in the uterus may cause adenomyosis.

What is the Relationship Between Adenomyosis and Infertility?



The age at which adenomyosis is most common is people between the ages of 40 and 50. Adenomyosis is a female disease related to the uterus. For this reason, we can say that adenomyosis is directly related to infertility and pregnancy. Adenomyosis is a disease whose incidence increases with increasing age, so infertility and adenomyosis can be seen together when pregnancy is considered in older women. Expectant mothers who encounter this situation can achieve their dreams of having a child by trying the in vitro fertilization method after receiving adenomyosis treatment.

What is Adenomyosis Treatment?



Experts have done many studies to treat adenomyosis disease and as a result, they have found various treatment methods. We can talk about hormonal therapy as the first treatment method. With hormonal therapy, it is tried to relieve the pain caused by adenomyosis and to reduce the excess blood. For this, birth control pills, temporary menopause treatments or medicated spiral methods can be used. As a second method, we can consider MRI Focused Ultrasound. In MRI focused ultrasound treatment, high-intensity heat waves are used to destroy the tissue that causes adenomyosis. Another form of treatment is hysterectomy. This form of treatment is the most permanent solution, but because it results in the removal of the uterus, it is applied only to women who do not plan to have children or in severe cases that do not respond to any treatment.

 In this article, we discussed adenomyosis, which is common in older women. What is adenomyosis, what are the causes of this disease, what is the relationship between adenomyosis and infertility, and what are the treatment methods for this disease, based on all these questions, we have made detailed explanations about adenomyosis for you. We wish you a pleasant reading. You can visit our website for more.

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Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.


What is blastocyst transfer?



Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.


What are the advantages of blastocyst transfer?



Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;

The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,

Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,

The chance to observe the embryo development more clearly and healthily,

Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,

· Allowing different methods to examine embryo viability.



What is the risk of blastocyst transfer?



The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.


Who is blastocyst transfer suitable for?



Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.

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Insemination treatment is a method of selecting the sperm that is the highest quality of the sperm taken from the expectant father during the ovulation period, that is, during the period when the probability of conception of the expectant mother is the highest, and then putting it into the womb of the expectant mother. A state of fertilization that has been tried many times by natural means, but no successful results have been obtained, thanks to vaccination treatment, sperm and egg dec easily combined and fertilized. So, how will expectant parents understand this situation when Insemination gives a successful result? We will answer this question and give you more detailed information about Insemination treatment. We wish you a pleasant reading in advance.



What is Insemination?


Insemination is a treatment applied by people who want to become parents but have not been able to achieve this condition by natural means. This treatment, which is performed before starting IVF treatment, is aimed at increasing the chances of pregnancy. Insemination takes place exactly as follows;

· Several necessary tests are applied to prospective parents before.

· Male sperm is taken and the best quality sperm is selected by special procedures.

* Spermatozoa are released into the uterus when the woman's eggs are laid. Here this process is known as the vaccination process.

The vaccination method is a method used in cases where the man's sperm count or mobility is low, when there are problems with the excretion of semen during intercourse, when the woman's cervix is narrow. The cause of infertility cannot be explained in any way.





To Whom Is Insemination Therapy Prescribed?


“Who is the Insemination method applied to?"we can explain the question as follows; It is a form of treatment applied to expectant parents who want to have children, but for various reasons some kind of pregnancy condition cannot be created. For the implementation of this treatment, the man or woman must have some problems that he is experiencing. We can list the problems encountered as follows:

· If there is a lack of sperm count and mobility in a man,

· If there is a problem of unexplained infertility (infertility)

· If the woman has ovulation problems and therefore pregnancy could not be done with egg tracking

· It can be applied in couples who want to accelerate the possibility of pregnancy due to social reasons experienced by couples.



What is the Success Rate of Insemination?


With the development of technology in the medical field and the scientific studies conducted, the success rate of Insemination treatment is quite high. And every day these treatments are being enriched with a new way and it is aimed to increase the success rate of Insemination to the highest level.







When Do the Symptoms of Pregnancy Begin With the Success of Insemination?


There is no difference between the occurrence of pregnancy with Insemination and the occurrence of pregnancy by natural means and the appearance of symptoms in terms of the occurrence of pregnancy Dec In other words, expectant mothers are 3rd of pregnancy, as in naturally occurring pregnancies. from the week she begins to experience signs of pregnancy. These symptoms can be considered as complaints such as dizziness, weakness, nausea and vomiting that occur in the morning. Expectant mothers who have these symptoms can find out if they are pregnant by taking a pregnancy test. 12-14 after Insemination to see if pregnancy has occurred. on the day, the Beta HCG hormone is checked in the blood and it is understood whether pregnancy exists or not. If the pregnancy result is positive, you will need to contact your doctor and undergo an examination to keep it under control. After this examination, a clearer result will be obtained by looking at it with ultrasound and it will be determined whether there is a pregnancy or not.

After Insemination, expectant parents should continue their normal lifestyle. They do not need to change anything in their lives with the introduction of Insemination therapy. In this process, they should only take care of regular and balanced nutrition and protect themselves in the best way. We have shared all the details of the vaccination method with you in this article. If you also want to become a parent and are looking for various treatment methods for this, you can check out our page.

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IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.



What is Comprehensive Chromosome Screening (NGS)?


It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.

Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.


What are the Features of the NGS Technique?




Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.


What Genetic Defects Can Be Detected with NGS-Based PGS?



Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.

To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.


Who are the Groups of Patients Who Can Be Administered NGS?




The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;

· In cases of repeated miscarriage,

· in expectant mothers over the age of 38,

· In severe male infertility,

* In cases of infertility, the cause of which is unknown,

· It is applied in cycles of continuous self-recurring treatment failures.

The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.


What are the Advantages of Preimplantastone Genetic Screening with NGS?




NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.


Does NGS Damage the Embryo?




IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.


Does Pregnancy Always Occur With a Smoothly Detected Embryo?




After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;

· Women's age

· The amount of ovarian reserve of the woman

* Sperm quality

· Embryo quality

· Ensuring a proper intrauterine environment

· The presence of hydrosalpinx

· Conditions encountered during embryo transfer

it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.

Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.

In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.


How Many Days Do NGS Results Come Out?



The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.

What are the NGS Test Prices?

The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.

In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.

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