IVF Treatment And Fertility
Every woman wants to feel the maternity. We try to see smiling on your face for that very small breath to be included into your world. We, as Huma IVF Center, plan to be with you in this process from the first step of your treatment to your birth with awareness of your infertility problems. We target to bring you together with the healthy individuals in your home while starting with the slogan ‘Let us Add Your Imagination into Your Life’, believe that you will feel safe and in peace in our center. We take the fair pride in presenting the high quality service to you with a principle trying to catch the world standards with our knowledge.
WHY IS HUMA IVF CENTER?
Our success in the assisted reproductive treatments is based on a team working in plan and in coordination.
Our team consisted of the gynaecologists, embryologists, nurses and the patient consultants expert at their subjects, open to share information shall be glad to give service to you in this way where you started in order to be able to have a child.
Huma IVF Center started out by making renewing itself every passing day in the infertility practices a rule. We are over the world standards at rates of pregnancy to be obtained by using the assisted reproductive techniques.
Our patient consultants are in your service in all stages of your treatments in order to ease the IVF center treatment processes of our patients who will come to our center for treatment from abroad. We enable accommodation at a discount in our contractual hotels and the transportation support, prepare the programs where you will be able to follow your treatment at a distance.
IVF Center Treatment Techniques
• TESE- TESA Practices
• PGT (Pre-implantation Genetic Diagnostic)
• Calcium Ionophore
• Intra lipid
• Asisted Hatching
• Microchip
• Embryoscopy
• Pool Method
• Uterus Resting
• PRP
Ear, Nose, Throat
Ear Nose Throat
In our Ear Nose and Throat Polyclinic, ear diseases such as ear infections, hearing loss, balance disorders and tinnitus, nasal congestion, nasal discharge, olfactory disorders, sinusitis, nasal diseases such as allergic rhinitis, throat diseases such as pharyngitis, tonsillitis, other rare diseases of the mouth and throat ; In addition to hoarseness, dysphagia and speech disorders, cancer diagnosis and treatment of the neck are performed. Our ENT polyclinic is equipped with devices and equipment that allow endoscopic examinations in addition to classical examination tools.
Nose Aesthetics (Rhinoplasty)
Rhinoplasty is an aesthetic operation performed to correct or reconstruct the appearance of the nose. Apart from visual purposes, rhinoplasty is also performed to eliminate structural defects that cause breathing problems. It is also a frequently performed surgery in the treatment of nasal fractures.
The size of the nose, shape and angle of the nose can be changed with Rhinoplasty (nose aesthetics), which is the most preferred operation among aesthetic surgeries and is performed to create a beautiful nose that is compatible with the face and liked by the person himself and his surroundings.
In which cases is rhinoplasty necessary?
• If the patient has aesthetic concerns
• If there are breathing problems due to various functional disorders
• In sinus problems
• In nasal fractures
• In case of cleft lip (with other operations)
• In severe facial burns
How Is Rhinoplasty Performed?
With the first examination to be performed by the surgeon, the patient's complaints, the desired visual changes and whether they are suitable for the nose or face structure are evaluated by sharing ideas between the doctor and the patient. With a detailed examination, it can be determined whether there is any problem in the nose that may prevent the rhinoplasty operation. In the absence of a structural problem, general health checks should also be carried out, and the presence of conditions that may interfere with the surgical operation, such as bleeding diseases, should be investigated. It is very important for the doctor and the patient to establish a good communication with the patient in terms of the shape changes to be made in the patients who are determined to be suitable for the operation, and to explain the patient's expectations to the doctor in a good way. The planning phase is completed by taking photographs of the nose from various angles.
When the day of the operation comes, general anesthesia is usually applied depending on the type of surgery. The duration of the operation also varies according to the procedures to be performed. On average, a rhinoplasty operation is expected to take approximately 1.5-2 hours. After the operation, which is performed by choosing the most suitable method for the patient, open or closed methods, the patients are discharged after being kept under observation for a certain period of time.
How long does the recovery process take in rhinoplasty?
After the rhinoplasty operation, it is of great importance to preserve the shape of the nose and the operation area in order to be successful in the treatment applications performed on the nose. Therefore, any trauma that will adversely affect the shape of the nose should be avoided. Apart from trauma, it is extremely important not to use heavy glasses, not to lie on your side or to apply pressure to the nose area for a period of time. After the surgery, resting adequately, especially for the first two or three days, and avoiding strenuous activities for a week will accelerate the healing process. In addition, medications prescribed by the physician should be used regularly. The control examinations given should not be interrupted, and if there is a dressing suggestion, they should be done regularly.
Today, rhinoplasty surgery gives extremely successful results thanks to the advanced techniques applied. Success in rhinoplasty means a nose that is both visually pleasing to the patient and performing its functions in a healthy way.
Who is suitable for Eyelid Aesthetics (Blepharoplasty)?
Eyelid aesthetics are mostly performed by individuals over the age of 35. It is possible for anyone with a medical need to have it done at any age. One of the first structures to show aging on the human face is the upper eyelid. Eyelid aesthetics (blepharoplasty) surgery cannot stop the ongoing aging of the eyelids; but the tired appearance on the face can be stopped for about 10 years.
How is upper eyelid aesthetics performed?
Upper eyelid aesthetics (blepharoplasty) or droopy eyelid surgery is the process of removing excess skin and fat tissue from the area due to the loss of tension in the skin. The surgical scar does not attract much attention as it will remain on the upper eyelid and will be open during the day. However, in order to avoid the scar, an incision is made from the eyelid fold line and aesthetic stitches are applied. Of course, this deformation of the skin does not occur only on the eyelid, so it gives better cosmetic results when applied together with forehead lift and eyebrow lifting operations.
In addition, interventions such as almond eye aesthetics along with upper eyelid aesthetics (blepharoplasty) are frequently preferred by patients.
How is lower eyelid aesthetics performed?
The fat pads located on the cheekbones atrophy (weak) with the effect of gravity along with the aging process. This causes signs of aging in the form of slumping or edema under the lower eyelid and prominent smile lines around the mouth. The lower eyelid should be evaluated by your physician and checked for bagging and sagging. The form of treatment should be evaluated. If surgery is required, the specialist physician should initiate the planning and process. In lower eyelid aesthetics, the surgical incision is made just below the eyelashes. The skin is lifted and the fat packets are removed. If the under-eye sunkenness continues after the surgery, an under-eye fat injection may be required after recovery.
How long does it take for Eyelid Aesthetics (Blepharoplasty) surgery and post-operative recovery?
After Eyelid Aesthetic Surgery, patients do not have serious pain. Movement is allowed, provided that it is nourished and not heavy. The patient, who is discharged on the same day, is evaluated again the next day and 5 days later. Stitches are often dissolving stitches. However, when necessary, the stitches are removed painlessly without waiting for them to dissolve. After the 5th day, it is allowed to shower and return to normal life. In order to reduce scars in Eyelid Aesthetics, scar reducing creams are sometimes recommended to patients.
Medical Aesthetic
Natural and artificial factors, especially aging, can cause the skin to lose its old appearance and become deformed. Surgical and non-surgical methods continue to be frequently preferred by people who are dissatisfied with their external appearance.
Hüma Hospital offers you health and beauty together in its Medical Aesthetics Clinic, which prioritizes professionalism and high-level technology.
BOTOX PROCESSES
What is Botox?
Botox , botulinum It is an abbreviation of the word toxin . Bacteria is a condensed type of protein. By acting on a substance called acetylcholine , which provides this communication between the brain and muscle , Botox prevents the contraction of small muscle groups that cause the appearance of wrinkles on the face and ensures that wrinkles are minimized.
It provides a more aesthetic appearance to the person by showing the effect of eliminating the appearance of wrinkled and old skin in a short time. Botox also provides expression design.
Because of the lines on the face, people who have an angry and stressful stance can easily get rid of this situation with botox .
How is Botox applied?
Botox application is done through a thin needle tip. Specially designed small injectors are used with a thin needle. The application is made to the muscle layer. During the Botox procedure, a slight burning sensation, like a needle stick, is felt. Other than that, no pain is felt. However, local anesthetic cream and ice are applied to sensitive individuals during the procedure.
How Long Does Botox Effect Last?
of Botox lasts up to 4-6 months. In repetitive botox applications, this period is prolonged in many patients. The effect of Botox does not end abruptly 4-6 months after it is made, it disappears over time. A person who has had botox for a long time will have fewer wrinkles than if he has never had botox, even after the procedure has lost its effect. That's why botox is also used as an anti-wrinkle treatment.
Facial Botox
Eye area Botox
Forehead Botox
Between Eyebrows Botox
Upper lip (Smoking lines) Botox
Lip Edge (sad face) Botox
Gummy Smile (The appearance of the gums when smiling) Botox
Upper Nose (Rabbit lines) Botox
Masseter (Chewing) Botox
Nefertiti (Neck and Decollete) Botox
Hands and palms Botox
Sweating Botox
Migraine Botox
FILLING PROCESSES
Nose Filling: It is a painless and painless procedure that provides an aesthetic nose appearance without the need for surgery in people who have problems such as curvature and symmetry in the nose area, droopy nose tip .
anesthetic cream is applied to the area to be applied, waiting for 15-20 minutes and the area is disinfected, and the filling material is injected under the skin in appropriate doses.
After this procedure, which lasts for an average of 1-1.5 years and takes about 15-20 minutes, the person can return to his daily life immediately.
The biggest advantage of nasal filling is that the desired shape can be given to the nose of the person. A better profile view can be obtained by filling the gaps in the main bone. In the same way, nasal tip deformities can be eliminated to a certain extent and the nose can be given a more upturned appearance.
Cheek-Cheek Filling : With the cheek filling technique, which is made to find practical and quick solutions to aesthetic problems on the face, volume deficiencies in the cheeks of the person can be successfully treated with an operation that takes 15 minutes. Hyaluronic acid filling , which is found in the natural structure of the skin, is generally preferred as a filling material.
Lip Filling : Lip augmentation, which is applied to add volume to the lips and increase their aesthetic appearance, is a painless filling process that takes 10-15 minutes.
Nasolabial Filling: Nasolabial lines , which are known as laugh lines among the people, appear more clearly when people laugh. With the nasolabial filling process, the appearance of deep pits is eliminated and the tissues in this area have a more vivid and fuller appearance.
Under-Eye Light Filling: Under-eye bags, bruises and swellings, depending on the genetic structure of the person, usually begin to become more pronounced in the 30s . With under-eye light filling, people's under-eyes get a healthy appearance without pain and pain. The permanence of this process, which is made by allowing the gel with a high water content of hyaluronic acid to dissolve in the body, is 1-1.5 years.
Chin and Jawline Filling:It is a method applied to people whose forward or backward stance in the chin impairs facial aesthetics or who want a more pronounced chin appearance. It is done by anesthetizing the person's chin area and injecting the appropriate dose of hyaluronic acid filler . The chin filling session takes about 15 minutes and the healing process is fast.
Temple Filling: It is a botox procedure that is performed to ensure facial harmony and makes the temples more pronounced .
PINK GLOW:
One of the most popular applications of the last period, which ensures the renewal of the skin, Paris Shine is one of the aesthetic applications performed to make the face shadow look younger and healthier.
How to Apply Paris Shine?
Local After skin cleansing, anesthetic cream is applied to sensitive individuals and waited for 20 minutes. It is then injected with a mesotherapy needle by forming a papule (with a slight swelling of the skin).
It can be applied to points of aging such as face, neck, décolleté and hands to give a fresher and brighter appearance. With the Paris glow, which can be repeated with certain sessions, the differences in your skin will show itself as vitality, brightness and youth, and you will feel more beautiful.
Face Lift with Rope Strap (French Strap): It is one of the non-surgical face rejuvenation methods with flexible ropes compatible with the human body to raise the tissue under the skin surface. People who are dissatisfied with their facial features and have complaints of wrinkles and sagging can make their choices with expert opinion Rope Strap alternatives according to their skin conditions.
Rope Axis Application Areas
In this method, although the application areas of the rope hanger may vary according to mimic movements, they are mostly the same. We can list the rope suspension application areas on the face and body as follows:
• cheeks
• Gill
• cheekbones
• oval line of the face
• forehead lines
• crow's feet
• Kas region
• Neck
Process time
• The patient does not feel pain or pain during the rope suspension application under local anesthesia.
• Depending on the procedure to be performed, the time may vary. However, it is usually completed in 20 minutes.
• There is no need for stitches in the rope suspension application applied to the patient.
• During the procedure, it is ensured that the threads are attached to the ear inside the head.
• In case of stretching for the body, rope hangers are attached to different areas.
• No clinical rest or home rest is required after the procedure.
• Individuals can return to their daily life.
PGD (Pre-implantation Genetic Diagnostic)
PREIMPLANTATION GENETIC DIAGNOSIS
In recent years, developments in genetics allow genetic analysis to be carried out on embryos developed in vitro by in vitro fertilization ethods and the placement of selected healthy embryos in the uterus of the mother before pregnancy occurs. This method is called pre- regnancy genetic diagnosis (Preimplantation Genetic Diagnosis-PGD).
One of the most important application areas of the PGT technique embryos that do not have a genetic disease but may not have a genetic disorder in their chromosomes.
These disorders are more common in women of advanced age (35 years and older). This situation may result in infertility as it both reduces the chance of attachment of the embryo (implantation) and may cause unwanted abortions. As a matter of fact, 40 out of every 100 pregnancies in women aged 39 and over have problems that occur due to a numerical chromosomal disorder
The aim of PGD is to increase implantation rates, reduce spontaneous abortions and increase healthy baby birth rates by selecting hromosomally normal embryos. Indeed, the miscarriage rate, which can reach up to 23 percent in normal pregnancy due to chromosomal disorders, may decrease to 9 percent after PGD.
Pre-pregnancy genetic diagnosis is performed by taking 1 or 2 cells from embryos developed as a result of fertilization of egg and sperm cells obtained from mother and father candidates in laboratory environment. Special methods called Fluorescence In Situ Hybridization (FISH), Microarray-based comparative genomic hybridization (aCGH) or Polymerase Chain Reaction (PCR) are used for genetic diagnosis. Diagnosis of numerical chromosomal disorders such as monosomy or trisomy (Down syndrome and other trisomies) and single gene diseases (such as hemophilia, Mediterranean anemia, cystic fibrosis, muscular dystrophies) in the baby to be born is possible with PGD. Thus, healthy babies are born by transferring disease-free, healthy embryos to the expectant mother.
DIAGNOSIS BEFORE PREGNANCY
- In couples with a genetic or hereditary disease carrier,
- In couples who have a child or children with a previous genetic disease,
- For the purpose of HLA genotyping (tissue typing),
- In the identification of diseases showing genetic predisposition (tendency)
- Women in the advanced age group (37 years and over) who have been accepted for assisted reproductive techniques,
- In couples with recurrent early pregnancy miscarriages,
- In couples who could not achieve pregnancy with assisted reproductive techniques despite multiple applications or who lost their pregnancy due to miscarriage,
- It is applied in cases of chromosomal disorders or genetic diseases associated with severe male infertility.
HOW IS THE PGT TEST DONE?
- Whether the patient is suitable for PGD is evaluated by the reproductive health specialist, genetic counselor and the doctor of the related disease.
- The couple is prepared for the IVF procedure.
- The egg taken from the mother is fertilized in the laboratory with the sperm taken from the father.
- 1-2 blastomere cells are removed from the obtained embryo by biopsy by embryologists
- Cells obtained by biopsy are prepared and tested according to the method to be applied.
- Embryos with genetic diseases or chromosomal disorders are selected and discarded and healthy embryos are transferred to the mothers womb.
Calcium Ionophore Application
It is a method of activating eggs and ensuring fertilization by using calcium ionophore (calcium ionophore) in cases where embryo transfer cannot be performed due to lack of fertilization during IVF treatment.
In the calcium ionophore application, first the egg and sperm are fertilized by micro-injection (ICSI); Then the eggs are kept in a medium containing calcium ionophore for a while. The main purpose here is to artificially increase the calcium level, which should increase in the egg after the sperm enters the egg. In other words, by supporting the reactions that should start in the egg, the egg is forced to be fertilized. With this procedure, a healthy fertilization and therefore a high pregnancy rate can be achieved.
Calcium ionophore therapy has been shown to be successful in the following situations:
- In patients with “globosperm” of all sperms
- If very few eggs or sperm are obtained
- Recurrent fertilization (fertilization) failures
- In cases where no fertilization can be achieved with micro-injection therapy
Microchip
In patients with low sperm viability, quantity, number and structural quality, microfluidic technology, also known as the "chip baby method", ensures that the best quality sperm cells are selected by competing with each other in a way similar to the natural environment in the uterus, and ICSI is defined in in vitro fertilization treatment. With the application, it is left into the egg cell by microinjection method.
In this method, sperm cells with the best structural form, genetics and physiology are selected without causing cell damage, since techniques such as centrifugation (settling), vortex (mixing with high vibration) or mixing with a pipette are not applied to the sperm cells, which can physically damage the sperm cells. In classical preparation methods, sperm cells are prepared in a shorter time without being subjected to manipulation by skipping processes such as washing, flotation, gradient (grading), centrifugation (precipitation at high speeds). Thus, the sperm cells with the best DNA quality and physiologically are selected by themselves, and the sperm cells that pass this pre-screening are again screened under the microscope and the sperm cells of excellent quality are used for microinjection.
The above-mentioned classical preparation methods cause sperm cells to undergo respiratory stress, known as oxidative stress, and it has been scientifically proven that this can also cause DNA damage in healthy sperm cells. Better quality embryos are tried to be obtained with sperm cells that have been proven to be of the best quality by scientific data, and thus embryos with the highest potential for implantation (attachment) and development are obtained. The average total mobility in suckling samples taken from male individuals with microchip technology increased by 1.7 times.
The sperm cells obtained by this method were found 3 times faster than the classical preparation methods, and the forward motile sperm cells increased 3.8 times.
Dietician Fatma Aybike BOZOKLU
Education:
2023 Nuh Naci Yazgan University faculty of health sciences
Work experience:
Çapa Faculty of Medicine Oncology Institute 2022
Areas of interest:
Nutrition in diseases
Nutrition after gastric sleeve surgery and stomach botox
sports nutrition
Pregnant and Breastfeeding Nutrition
Nutrition in diabetes
Baby-child-adult nutrition
Getting fat
Allergy-food intolerance and nutrition
Losing weight
Adequate balanced and healthy nutrition
Nutrition in eating behavior disorders
weight maintenance
institutional nutrition
sports nutrition
Md. ADEM ARIK
INTEREST AREAS
Premature Baby Follow-up and Treatment
Neonatal Intensive Care Treatments
Neonatal Jaundice
Healthy Child Follow-up
Growth Follow-up and Evaluation in Children
Infection in Children
Respiratory Disorders in Children
Loss of Appetite in Children
EDUCATION
Hacettepe University Faculty of Medicine
Atatürk University Faculty of Medicine Child Health and Diseases Clinic
WORK EXPERIENCE
2021 – Present Private Hüma Gynecology and Obstetrics Hospital
2018-2021 Kayseri City Hospital
2012 -2018 Kayseri Education and Research Hospital
2010 – 2012 Kırıkkale State Hospital
2008 – 2010 Private Elif Children's Center
2005 -2008 Kırıkkale Gynecology and Obstetrics Hospital
2002 -2005 Keskin State Hospital
MEMBERSHIPS
Kayseri Medical Chamber
How many times can IVF treatment be tried?
IVF treatment, which is preferred by couples who cannot conceive naturally and cannot have children, is a source of hope for couples who cannot have children due to the development of medicine and technology. IVF treatment is the fertilization of male and female reproductive cells outside the body under laboratory conditions. Currently, couples have a 95 percent chance of success with IVF treatments. IVF treatment is one of the most successful methods in the treatment of infertility, the cause of which is not clear, or which cannot be conceived in the most natural ways. If couples do not succeed in their first attempts at IVF treatments, they should not despair and stress immediately. Because there are no restrictions on IVF treatment.
How many times can IVF treatment be tried?
A study conducted on couples undergoing IVF treatment shows that the rate of achieving pregnancy in couples after the first three trials is 95 percent. In addition, no number can be given about the number of treatments in the remaining group. The experts are also 4. or 5. there is an opinion that the chances of IVF success in trials are slightly lower than in the first three trials. The success rate of IVF treatment does not depend on many attempts. Multiple factors, such as the age of the couples, obtaining a quality embryo, affect the success rate of IVF treatment at a critical point.
Is Success Achieved in the First Attempt in IVF?
The chances of pregnancy during the one-month treatment period with the insemination method or ovulation treatments are about 20% or slightly more than the chances of a healthy couple becoming pregnant in a month. These treatments can be tried 3 or 4 times until pregnancy is achieved, but most of the pregnancies are obtained in the first months of treatment. Continuing treatment for more than 4 years will not increase the chances of pregnancy, so you can switch to IVF treatment.
Currently, thanks to newly developed methods and applications, the success rate of in vitro fertilization treatment is gradually increasing, if success is not achieved at the first attempt, repeated attempts can be made. The chance of becoming pregnant in a month with IVF treatments varies depending on age, but on average it is up to 50-60%. Pregnancy rates can increase by more than 90% after 4 applications when more than one treatment is performed in a row. For this reason, the chances of becoming pregnant increase with the number of attempts in couples who do not have a specific problem.
WHAT IS SECONDARY INFERTILITY?
In some cases, it is not enough if only the reproductive system is healthy for pregnancy to occur. Along with the reproductive system, it is extremely important for the pregnancy process that many factors work in harmony with each other. Depending on the factors that affect the process, pregnancy may not occur in people. This condition can also be observed if the person has already become pregnant or had a healthy birth.
Infertility, which occurs as a result of a couple having regular sexual intercourse for 12 months and not being able to get pregnant even though they are not using a method of protection, can be seen in two different ways. Never before pregnancy occurs when primary infertility; a live birth or not, regardless of if at least one pregnancy occurred, secondary (secondary) infertility is defined as.
You can continue reading our article about what is secondary infertility, what are its causes, important risk factors and treatment topics.
Causes of Secondary Infertility
Secondary infertility can occur due to both of the couples. The causes of secondary male infertility; the presence of varicose veins in sperm vessels, known as varicocele, infections, traumas and testicular tumors can be listed in the form of. The causes of secondary infertility in women are causes such as differences in ovulation patterns, damage or blockage of the tubes, deterioration of the structure of the uterus, and cervical and cervical cancer, especially as age progresses.
Autoimmune diseases and sexually transmitted diseases are also among the causes dec lead to secondary infertility.
In order to determine which of the many factors considered to cause the development of secondary infertility in people and to make appropriate planning, the couple should consult a specialist physician.
Risk Factors for Secondary Infertility
One of the most curious points about secondary infertility is the risk factors of secondary infertility. Many risk factors can cause the development of secondary infertility in people. These factors;
• Progression of age
• Different disorders such as polycystic ovary syndrome
* Excess weight
• Previous miscarriages
* Stress
* Alcohol, smoking and substance use
It can be sorted as follows. Along with all this, various factors that may differ from person to person can also lead to the development of secondary infertility in people.
Treatment of Secondary Infertility
The causes of secondary infertility, which are an obstacle to a person's conception, can be studied in an extremely wide range. For this reason, first of all, the points that prevent a person from becoming pregnant should be determined by taking into account different factors and an appropriate treatment plan should be developed accordingly. As a result of the evaluations made by taking the patient's history, vaccination and IVF treatments may be recommended to support conception. In order to determine the condition, specific infertility tests can be administered to people after a physical and pelvic examination. The ovulation test and other hormone tests are some of them.
As Huma IVF center, we continue to be with you in this process with our expert staff. For all the questions you have in mind, you can contact us by checking out our experts on our website.
WHAT IS THE SPERMIOGRAM TEST FOR ANALYSIS OF SPERM CELL?
Parents who want to have children generally prefer the most common in vitro fertilization treatment. Before this treatment, both mother-to-be and father-to-be go through many tests. Father-to-be passed; The first of the tests to test for infertility or other problems is the sperm test, also known as the spermiogram test. What is the spermiogram test for the analysis of the sperm cell? How is spermiogram done? What do spermiogram test results mean? We will answer all these questions for you in detail below. We recommend that you continue reading our article to have detailed information about the sperm test.
What is a test (spermiogram)?
Sperm test done to men; It is a test to determine sperm health, sperm count, and whether the sperm are moving correctly in the channels. As a result of the sperm test, if the sperm shape is normal and there is a sufficient number of sperm, it is concluded that your reproductive ability is high. However, in some cases, men may have low sperm count or the ability to reproduce despite having abnormal semen. That's why doctors order a second test for the accuracy of the results. If your results are normal in your first sperm test, you give the other test and if it is normal, these two normal tests show that you do not have an infertility problem. If there are different conditions, your doctor may order other tests.
If there is no semen or sperm as a result of the sperm test, this may indicate that your ducts are blocked. If this is the case, your doctor will plan different surgeries to open the channels.
Issues and Precautions to Consider While Giving Sperm Sample
There are important points to be considered before giving the sperm sample and while giving the sperm sample. Among the things to be considered before giving a sperm sample, we can count that "men should abstain from sexual intercourse for 3 days". Fasting for 3 to 5 days is sufficient. These numbers are important because if you fast for less than 3 days, the sperm count may be low as a result of the sperm test. For this reason, we can say that fasting between 3 and 5 days is sufficient. It is possible to list the issues to be considered while giving a sperm sample as follows;
· Storing the sample in a sterile environment: It is important to protect your sample from the outside environment for a healthy and accurate spermiogram test result. If a sterile environment is not provided, the test result may be inaccurate. Therefore, do not put your hands, especially sample containers, etc. It is important that you keep it as sterile as possible.
· Protecting the delivered sperm from heat: Another important point is to keep your sample away from extreme temperature changes after ejaculation. Because these extreme temperature changes negatively affect spermatozoa. Ideal temperatures for the sample cup should be between 20°C and 37°C.
· Sperm volume, amount: Volume is extremely important in the sperm test. Your sperm volume is expected to be at least 1.5 ml. The reason why you cannot reach the lower limit of 1.5 ml may be external discharge during ejaculation. It is important to be careful about this.
· Use of lubricating foreign substances during the sperm test: It is important not to use any lubricant during the sperm test because these substances seriously affect the sperm parameters. External factors with such an impact can lead to wrong conclusions.
How is the Sperm Test Done?
For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.
Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.
Issues and Precautions to Consider When Analyzing Sperm Sample
For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.
Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.
Issues and Precautions to Consider When Analyzing Sperm Sample
After the sperm test is given by the prospective fathers, it is examined in the laboratory environment. This examination takes approximately 1-2 hours and after the first hour, active results begin to be obtained. However, sometimes different situations can be encountered. For example, the test is given, but no sperm can be seen when looked at. In these cases, sperm are taken again and centrifuged. When faced with such a situation, the time may be extended. If there is no additional test to be done, the test results are immediately available in an average of 1-1.5 hours.
What Do Sperm Test Results Mean?
Sperm test results can be evaluated in many ways. Sperm analysis evaluates the sperm by analyzing it from various aspects. We can list these analyzes as follows:
· Sperm count and density:
Sperm count describes the number of sperm in 1 ml of semen. The World Health Organization advocates that a normal sperm count should be at least 15 million per ml or at least 39 million per sample. Having fewer sperm than these numbers indicates a low sperm count.
· Sperm morphology:
Non-abnormal sperm have a long tail and oval head. Morphology refers to the size and shape of the sperm a person has. Sperm that do not have a normal size or are weak in shape have difficulty reaching the egg and fertilization.
· Sperm motility:
The ability of sperm to move efficiently is one of the most important factors for fertilization.
· PH level of sperm:
When the pH level is too high or too low, it can affect the health of sperm and its ability to pass through the female reproductive tract.
Apart from these, sperm health is examined by looking at many factors such as semen volume, liquefaction, and seminal fructose levels while performing the sperm test. After examining all factors in detail, the results are examined and reported to the patient.
What is the Sperm Test Result of a Healthy Individual?
Low sperm count can have many different causes. The first reason is smoking addiction. Smoking addiction is one of the important factors that reduce the sperm count. In addition to smoking, alcohol and drug addiction also affect sperm count. Sperm count can also be adversely affected when there is a deficiency in hormones, depending on the clogged ducts.
Hormones are one of the important factors for reproduction on their own. Since the deficiency in reproductive hormones directly affects sperm production, it increases the possibility of encountering problems in reproduction. Apart from these, mistakes made by couples who want to have children also affect the sperm count. Using natural products unconsciously and continuing to use them uncontrollably, without knowing the limit, does harm to the person instead of providing benefits. Long-term treatment and drugs used during the treatment also affect the sperm count.
IMSI in Sperm Selection
The IMSI (Intracytoplasmic Morpholgically Selected Sperm Injection) method is the magnification and examination of even the smallest cells using special microscopes. In the past, in the microinjection procedures applied in IVF treatments, living sperm cells could be enlarged up to 400 times. However, with IMSI, sperm can now be enlarged between 6000 and 8000 times. It is possible to examine and detect in detail the disorders called "vacuoles" that indicate the intracellular structures of the sperm and their genetic damage.
The IMSI technique is an extremely useful method. Selected sperm injection; It allows advanced morphological analysis of sperm without damaging the living sperm cell. Sperm with the highest fertilization ability are selected and a high chance of fertilization between 20% and 40% can be obtained with the applied microinjection application.
Precautions to be Considered for Sperm Quality
Couples who want to have children should pay attention to egg and sperm health and be careful in this regard. There are many factors that affect sperm quality, such as those that affect egg quality. One of these factors is undoubtedly a healthy diet. A healthy diet is extremely important for every organ in the body, of course also in sperm health.
In addition, exercise is very important in making you more vigorous and increasing your body's stamina and activity. Regular exercise will make you recover in a short time and will positively affect both your mental and physical health. Alcohol and smoking are substances that affect reproductive cells and should be avoided. This is a proven fact as a result of research. If we gather all these under one title, we can say that one should take care of his own health. Nutrition, avoiding alcohol, smoking, exercising regularly will first affect your health and therefore your sperm quality.
This process, which is sensitive and special for couples who want to have a child, is extremely important for them. In this process, prospective parents experience excitement on the one hand and a lot of stress on the other. Hüma IVF Center, which understands the emotions experienced best and does not spare its support by being by their side throughout the process, is always ready to accompany you.
WHAT IS BETA HCG? HOW MUCH BETA HCG VALUE SHOULD BE? WHAT DOES ITS LOW AND HEIGHT MEAN?
Beta HCG hormone is a hormone known as the pregnancy hormone among the people. It is used in pregnancy tests to determine whether the person is pregnant or not. Experts express the test to measure the beta HCG hormone in different ways. You may have heard of Beta HCG blood test, quantitative blood pregnancy test, quantitative HCG test, and quantitative serial Beta HCG test. In this article, we have brought together all the curious about Beta HCG. What should be the Beta HCG value? What does low or high Beta HCG mean? Read on for the answers to all these questions.
What is Beta HCG?
There are 2 types of HCG Hormone, Beta and Alpha. During the pregnancy test, the Beta hormone is examined and is called Beta HCG. Beta HCG hormone is secreted by the placenta with the occurrence of fertilization. A blood test is performed between 10 days and 14 days after fertilization, and a high value can be observed in Beta HCG hormone as a result of the blood test. After a day or two, a urine test is done and more precise data for pregnancy can be obtained. High beta hcg hormone does not only mean a sign of pregnancy. Depending on some diseases encountered in people, its level in the body may increase, this varies from person to person. For this reason, when a high level of Beta HCG hormone is detected, different tests are performed immediately and it is ensured whether pregnancy has occurred or not.
What Should Beta HCG Value Be?
In a healthy non-pregnant woman, Beta HCG hormone varies in the range of 0-10 mlU/ml. In fact, it is usually seen at values around 0 and 0. With pregnancy, these values increase. In other words, we can understand whether pregnancy exists or not from the height of this hormone.
What Does Low and High Beta HCG Mean?
Beta HCG elevation first suggests that the person is pregnant. Because pregnancy increases the Beta HCG hormone. This hormone may give false information in some periods. Especially if the person has a different ailment, for example; In cases such as gastritis, some types of pancreatic cancer, some stomach cancers, ovarian cancer, liver tumor, multiple pregnancy, high levels of this hormone can be detected. For this reason, it is not possible to understand that you are pregnant with this test alone. Afterwards, you must have different tests. In addition to these, it is possible to say that the foods eaten also affect this hormone. Foods high in progesterone such as dill, avocado, spinach, tomatoes and walnuts increase the Beta HCG value.
Beta HCG is usually 0 and close to 0 in normal, ie non-pregnant individuals. In individuals who are pregnant, the low level of this hormone may be due to many reasons. These; ectopic pregnancy, deviation in the calculation of the week of pregnancy, sudden miscarriages.
In this article, we have discussed the Beta HCG hormone in detail. We have made explanations for you by giving place to all the questions that are curious. For more, you can visit our Hüma IVF page.
WHAT IS THE INTRA-LIPID SERUM PROCEDURE AND HOW TO USE IT?
Serum Intralipid Therapy is a treatment used specifically to strengthen the immune system. The immune system plays a big role in the repeated IVF failures and recurrent miscarriages seen in some women. For this purpose, intralipid serum therapy is also used. This is a type of treatment that is started prior to IVF treatment and is applied once a week or every two weeks until the baby's heartbeat is heard, if deemed necessary after pregnancy is achieved. Now let's take a closer look at intralipid serum treatment together ...
What is Intralipid Serum Therapy?
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Intralipid serum therapy is a form of treatment that starts on the day of the transfer and continues throughout the process. Intralipid whey contains fat molecules and soy protein, which strengthens the immune system. The immune system is extremely important for a healthy pregnancy and its continuation. Because half of the child belongs to the father, the mother's body does not reject it. In vitro fertilization failure also occurs in case of rejection, but intralipid therapy can prevent this failure.
For whom and how is intralipid serum treatment applied?
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Intralipid Serum Therapy is an immune-boosting treatment that is commonly used in women with recurrent miscarriage problems and recurrent IVF failures. As a result of studies, it was found that treatment with intralipid serum does not have side effects. Only women can be allergic to some substances in the serum of intralipid, in which case this should be determined in advance. These substances are a number of special ingredients such as glycerin, egg phospholipids. It is preliminarily checked whether the patient is allergic to these substances. If the patient has an allergy, treatment is not applied.
Intralipid whey treatment is carried out with a preparation containing emulsified oil prepared with a special concentration, which takes approximately 45 minutes. Fatty sera are administered to the patient intravenously.
In this article: what is serum intralipid therapy, who is this treatment for, how is intralipid therapy used? We have answered all these questions for you. If you want to get more detailed information about this, we recommend that you visit the website of the HUMA center.
WHAT IS A REDUCED OVER RESERVE (AMH)?
Ovarian reserve, known as the ovary, is a term used to determine the fertilization ability of the ovary to provide egg cells and to determine the probability of a successful pregnancy. With the advancing age of the expectant mother, the number of egg cells obtained from the follicles for pregnancy decreases. decreased ovarian reserve (AMH); It is a condition in which the ovaries begin to lose their normal production capabilities, reducing fertility. Decreased ovarian reserve reduces women's chances of conceiving spontaneously or with treatment. However, it is aimed to minimize the effects of this situation with various methods. The main causes of decreased ovarian reserve can be listed as follows:
· Smoking,
Chronic diseases,
Coffee consumption
Age of the expectant mother,
Genetic abnormalities (X chromosome abnormalities)
Various treatments (such as radiation for cancer)
· Having undergone ovarian surgery.
You can continue reading our article for reduced ovarian reserve and all its details.
How to Identify Decreased Ovarian Reserve?
Decreased ovarian reserve is determined by examining the hormone tests to be performed on the 2nd or 3rd day of the menstrual period of the expectant mother. FSH hormone gives information about the status of ovarian reserves. If the FSH value is higher than 10, it indicates decreased ovarian capacity.
The best indication of the capacity of the ovaries is the vaginal ultrasound. Existing and developing egg structures can be easily detected here. If there are less than six egg structures in the total ovaries, decreased ovarian reserve may be in question.
In summary, decreased ovarian reserve; It can be understood by clinical evaluation of the person, vaginal ultrasound, measurement of AMH hormone and FSH hormone in the blood.
Can a Woman with a Decreased Ovarian Reserve Get Pregnant?
Existing studies show that women with reduced ovarian reserve can become pregnant both spontaneously and with IVF treatment. Although it has been shown that high serum FSH levels in women are associated with low pregnancy rates, it is not sufficient to make a decision based on this alone. Egg cells also regulate their size under the influence of genetic factors. The speed of the aging process of the ovaries varies greatly among women, except for the age factor. In addition to the successful results of endocrine tests and imaging methods in the numerical evaluation of ovarian reserve, their values in determining the chance of pregnancy remain at a limited level.
The chance of conceiving of a woman who is determined to have decreased ovarian reserve with ovarian reserve tests and clinical evaluations by specialist physicians can be increased by applying appropriate ovulation treatment protocols. Patients with reduced ovarian reserve can become mothers with different techniques today. In order to determine these methods, it is important to plan and apply special treatment methods suitable for patients by considering various factors.
How Is Decreased Ovarian Reserve Treated?
Currently, there is no treatment for decreased ovarian reserve that prevents or slows down ovarian aging. In addition, lifestyle changes have an extremely important role in preventing premature aging of the ovaries and in order to ensure the healthy continuation of egg quality, that is, to increase egg reserve and quality. These;
· Eating a balanced and healthy diet,
Doing regular exercise,
Quality and adequate sleep,
Avoiding chemicals, high glycemic index and fast food style foods,
Not to use substances such as cigarettes and alcohol,
· Using antioxidant drugs under the control of a physician.
If you have decreased ovarian reserve and want to have a child according to your required tests and vaginal ultrasound results, it is extremely important to seek in vitro fertilization treatment in the presence of a specialist doctor, without wasting time.
As Hüma IVF Center, we choose the most appropriate treatment method for you, apply it and continue to serve.
WHAT IS BLASTOCYST TRANSFER? WHAT ARE THE ADVANTAGES OF BLASTOCYST TRANSFER?
Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.
What is blastocyst transfer?
Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.
What are the advantages of blastocyst transfer?
Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;
The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,
Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,
The chance to observe the embryo development more clearly and healthily,
Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,
· Allowing different methods to examine embryo viability.
What is the risk of blastocyst transfer?
The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.
Who is blastocyst transfer suitable for?
Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.
CALCIUM IONOPHORE THERAPY
Calcium ionophore therapy is a treatment method applied to ensure a healthy fertilization and to obtain a high pregnancy rate. In order to talk about a healthy fertilization, when the sperm enters the egg, the enzyme in the head part of the egg must be released into the egg and the amount of calcium inside must increase.
If the amount of folfolipase C in the sperm is low, the egg cannot be fertilized because without phospholipase, the calcium rate in the egg does not increase.
Calcium ionophore therapy is an application that increases the amount of calcium in the egg. In the calcium ionophore application, the egg and sperm are first fertilized by micro-injection. After this process, the eggs are kept in a calcium ionophore for a few minutes. The main purpose here is to increase the calcium level that needs to be increased in the egg. In other words, calcium ionophore therapy helps the fertilization of the egg by supporting the reactions that should start in the egg. So, what is calcium ionophore therapy and to whom is it applied? Now we will answer all these questions for you.
What is Calcium Ionophore? To Whom Is It Applied?
It is possible to define calcium ionophore therapy as an application that increases the amount of calcium in the egg. This treatment method is generally applied to the people we will list below. Those people;
Individuals with successive fertilization problems
If very few eggs or sperm are obtained
In cases where no fertilization can be achieved with micro-injection therapy
In patients with “globosperm” of all sperms
Calcium ionophore therapy is applied.
Who Is Fertilized With Calcium Ionophore?
In cases where embryo transfer cannot be performed due to the fertilization step not taking place during IVF treatment, activation of the eggs and fertilization are aimed by using calcium ionophore. Thus, calcium ionophore therapy is applied. With this treatment method, the problem of non-fertilization can be eliminated and treatment can be applied in couples who have non-fertilization problems. This treatment method is also applied to couples who have problems as a result of obtaining a very small amount of egg and sperm. Fertilization is performed with the calcium ionophore treatment method and a high pregnancy rate is obtained.
In this article, we have given the answers to all these questions for you, what is calcium ionophore therapy, to whom this treatment method is applied and in whom fertilization occurs as a result of the treatment.
It may interest you: What is infertility, what are its symptoms, what kind of treatment method is applied?
WHAT IS BETA HCG? WHAT SHOULD BE THE BETA HCG VALUE? WHAT DOES ITS LOWNESS AND HEIGHT MEAN?
The hormone beta HCG is a hormone that is popularly known as a pregnancy hormone dec It is used in pregnancy tests to determine whether a person is pregnant or not. Specialists express the test for measuring the hormone beta HCG in different ways. It is possible to hear it in the form of a beta HCG blood test, a quantitative blood pregnancy test, a quantitative HCG test, and a quantitative serial Beta HCG test. In this article, we have collected all the curiosities about Beta DECG. What should be the beta HCG value? What does it mean if the beta hCG value is low or high? For answers to all these questions, continue reading our article.
What is Beta HCG?
There are 2 types of the Hormone HCG - Beta and Alpha. When conducting a pregnancy test, the Beta hormone is examined and called Beta HCG. The hormone beta HCG is secreted by the placenta with the formation of fertilization. A blood test is performed dec 10 days and 14 days after fertilization, and as a result of the blood test, a high value of the hormone Beta HCG can be observed. After a day or two, a urine test is performed and clearer data for pregnancy can be obtained. The height of the hormone beta hcg means not only a sign of pregnancy. Depending on some diseases that are found in people, their level in the body may also increase, it varies from person to person. For this reason, when an increase in the Beta HCG hormone is detected, different tests are also performed immediately and it is made sure that the pregnancy does not occur.
What Should Be the Beta HCG Value?
In a healthy woman who is not pregnant, the hormone December HCG varies in the range of 0-10 mlU/ml. Even it is usually seen at an approximate value of 0 and 0. With pregnancy, these values increase. That is, we know from the height of this hormone whether pregnancy exists or not.
What Does Low And High Beta HCG Mean?
The height of beta hCG first makes it clear that the person is pregnant. Because pregnancy increases the hormone Beta HCG. This hormone can give false information in some periods. For example, if a person has a different condition, gastritis, some types of pancreatic cancer, some stomach cancers, ovarian cancer, liver tumor, and multiple pregnancy, this hormone can also be elevated in cases such as gastritis. Therefore, it is unlikely that you will understand that you are pregnant only with this test. After that, you must also have different tests. In addition to these, it october possible to say that the nutrients eaten also affect this hormone. Foods high in progesterone, especially dill, avocado, spinach, tomatoes and walnuts, increase the value of Beta HCG.
Beta HCG is normal, that is, it is usually close to 0 and 0 in individuals who are not pregnant. In individuals who are pregnant, a low level of this hormone can be due to many reasons. These are ectopic pregnancy, a deviation in the calculation of the week of pregnancy, sudden miscarriages.
In this article, we have discussed the Beta HCG hormone in detail. We have made explanations for you by including all the questions that are curious. For more information, you can visit our Human IVF page.
WHAT IS COMPREHENSIVE CHROMOSOME SCREENING (NGS)?
IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.
What is Comprehensive Chromosome Screening (NGS)?
It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.
Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.
What are the Features of the NGS Technique?
Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.
What Genetic Defects Can Be Detected with NGS-Based PGS?
Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.
To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.
Who are the Groups of Patients Who Can Be Administered NGS?
The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;
· In cases of repeated miscarriage,
· in expectant mothers over the age of 38,
· In severe male infertility,
* In cases of infertility, the cause of which is unknown,
· It is applied in cycles of continuous self-recurring treatment failures.
The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.
What are the Advantages of Preimplantastone Genetic Screening with NGS?
NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.
Does NGS Damage the Embryo?
IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.
Does Pregnancy Always Occur With a Smoothly Detected Embryo?
After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;
· Women's age
· The amount of ovarian reserve of the woman
* Sperm quality
· Embryo quality
· Ensuring a proper intrauterine environment
· The presence of hydrosalpinx
· Conditions encountered during embryo transfer
it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.
Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.
In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.
How Many Days Do NGS Results Come Out?
The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.
What are the NGS Test Prices?
The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.
In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.
Foods That Boost Fertility: A Nutritional Guide for IVF Patients
Foods That Boost Fertility: A Nutritional Guide for IVF Patients
Embarking on an IVF journey can be both exciting and overwhelming. While medical advancements have significantly increased the chances of conception, diet plays a crucial role in supporting reproductive health and improving IVF success rates. A well-balanced diet rich in essential nutrients can enhance fertility, regulate hormones, and improve overall well-being. In this guide, we will explore the best fertility-boosting foods for IVF patients.
1. The Role of Nutrition in IVF Success
Nutrition has a direct impact on reproductive health. A diet rich in antioxidants, healthy fats, vitamins, and minerals can improve egg quality, support embryo development, and enhance uterine health. Conversely, unhealthy eating habits, excessive processed foods, and trans fats may negatively affect fertility.
2. Fertility-Boosting Foods for IVF Patients
A. Antioxidant-Rich Foods
Antioxidants help reduce oxidative stress, which can damage egg and sperm cells. Incorporate these antioxidant-rich foods into your diet:
Berries (strawberries, blueberries, raspberries) – High in vitamin C and folate.
Dark leafy greens (spinach, kale, Swiss chard) – Loaded with folic acid and iron.
Nuts and seeds (walnuts, almonds, flaxseeds, chia seeds) – Contain vitamin E and selenium, crucial for reproductive health.
Dark chocolate (with at least 70% cocoa) – Rich in flavonoids that support blood circulation to reproductive organs.
B. Healthy Fats
Healthy fats are essential for hormone production and egg quality. Opt for:
Avocados – A great source of monounsaturated fats that promote hormone balance.
Olive oil – Anti-inflammatory properties support embryo implantation.
Fatty fish (salmon, sardines, mackerel) – Rich in omega-3 fatty acids, crucial for reproductive health.
Nuts and seeds – Provide healthy fats and essential micronutrients.
C. Protein Sources
Protein is vital for cell development and hormone production. Prioritize:
Lean meats (chicken, turkey, lean beef) – Provide high-quality protein and iron.
Eggs – Contain choline and vitamin D, essential for fertility.
Legumes (lentils, chickpeas, beans) – Plant-based proteins that boost hormonal balance.
Greek yogurt – A probiotic-rich dairy option that supports gut health and nutrient absorption.
D. Whole Grains
Whole grains provide sustained energy and improve insulin sensitivity, which is crucial for reproductive health. Include:
Quinoa – A gluten-free, protein-rich grain with essential amino acids.
Brown rice – Supports blood sugar balance and ovulation.
Oats – High in fiber, promoting digestive health and hormonal balance.
Whole wheat bread – Provides essential B vitamins for reproductive function.
E. Hydration and IVF Success
Proper hydration is key to reproductive health. Drinking enough water helps maintain cervical mucus, improves egg health, and enhances nutrient absorption. Aim for at least 8-10 glasses of water daily, and include herbal teas like ginger or peppermint for additional benefits.
3. Foods to Avoid During IVF Treatment
Certain foods can negatively impact fertility and IVF success. Limit or avoid:
Processed foods – High in trans fats and artificial additives that disrupt hormonal balance.
Excess caffeine – May reduce fertility and interfere with implantation.
Sugary foods and beverages – Can cause insulin spikes, affecting ovulation.
Alcohol – Lowers fertility rates and negatively impacts egg and sperm quality.
Soy-based products – Excessive soy can disrupt estrogen levels.
4. Final Tips for a Fertility-Boosting Diet
Follow the Mediterranean diet – This diet, rich in whole foods, healthy fats, and lean proteins, is linked to improved IVF success rates.
Maintain a balanced meal plan – Aim for variety and include a mix of macronutrients.
Consult a nutritionist – If needed, seek guidance for a personalized diet plan.
Stay active and manage stress – Regular physical activity and stress reduction techniques, such as yoga or meditation, can further support fertility.
Conclusion
A fertility-focused diet can significantly enhance IVF success rates by improving egg quality, regulating hormones, and creating an optimal environment for conception. By incorporating nutrient-dense foods and avoiding fertility-disrupting substances, you can support your journey toward parenthood. Always consult with your fertility specialist or nutritionist to tailor a diet plan suited to your specific needs.
Are you ready to take charge of your IVF journey through nutrition? Start today by making small, healthy changes that will benefit your reproductive health and overall well-being!
How to Improve Egg Productivity & Quality
How to Improve Egg Productivity & Quality
Fertility is a crucial aspect of reproductive health, and for women, egg productivity and quality play a vital role in conception. The number and quality of eggs naturally decline with age, but various lifestyle changes, diet improvements, and medical interventions can help maintain and enhance ovarian health. Whether you are planning for pregnancy now or preserving fertility for the future, here are some effective ways to boost egg productivity and quality.
1. Maintain a Balanced and Nutrient-Rich Diet
What you eat directly impacts your reproductive health. A fertility-friendly diet should include:
Antioxidants: Found in berries, nuts, and leafy greens, antioxidants help protect eggs from oxidative stress.
Healthy Fats: Avocados, olive oil, and nuts support hormonal balance and egg cell membrane integrity.
Protein Sources: Include lean meats, fish, eggs, and plant-based proteins like beans and lentils to promote healthy egg development.
Folic Acid & B Vitamins: Essential for cell division and DNA synthesis. Found in leafy greens, citrus fruits, and fortified grains.
Omega-3 Fatty Acids: Found in salmon, flaxseeds, and walnuts, they enhance egg quality and overall reproductive health.
2. Stay Hydrated
Drinking enough water is essential for circulation and nutrient transport to the ovaries. Dehydration can negatively affect egg development and hormone production.
3. Maintain a Healthy Weight
Being overweight or underweight can disrupt hormonal balance and ovulation. Maintaining a BMI within a healthy range supports regular ovulation and egg maturation.
4. Reduce Stress Levels
Chronic stress increases cortisol levels, which can interfere with reproductive hormones and egg development. Stress management techniques include:
Meditation & Yoga: Help regulate stress hormones and improve blood flow to reproductive organs.
Regular Exercise: Moderate physical activity boosts circulation and hormone regulation.
Adequate Sleep: 7-9 hours of quality sleep each night supports hormone balance and overall health.
5. Avoid Toxins and Harmful Substances
Reduce Caffeine & Alcohol: Excessive intake can negatively affect fertility.
Quit Smoking: Smoking accelerates ovarian aging and reduces egg quality.
Limit Exposure to Environmental Toxins: Pesticides, plastics (BPA), and heavy metals can harm egg health. Opt for organic foods and use BPA-free products.
6. Take Fertility-Boosting Supplements
Certain vitamins and supplements can enhance egg quality:
Coenzyme Q10 (CoQ10): Improves egg cell energy and mitochondrial function.
Vitamin D: Supports ovarian function and hormonal balance.
Zinc & Selenium: Help protect eggs from oxidative stress and improve overall reproductive health.
DHEA (Dehydroepiandrosterone): A precursor hormone that can help improve ovarian reserve in some cases (consult a doctor before use).
7. Consider Medical Interventions if Necessary
If you are struggling with fertility issues, consult a specialist who may recommend:
Hormonal Therapy: Helps regulate ovulation and improve egg development.
Ovulation Induction Medications: Clomiphene citrate or Letrozole can stimulate egg production.
IVF (In Vitro Fertilization): If natural conception is difficult, IVF can retrieve multiple eggs for fertilization.
PRP (Platelet-Rich Plasma) Therapy: An emerging treatment that may help rejuvenate ovarian function.
8. Monitor Your Ovarian Reserve
Regular fertility check-ups can help assess egg quality and quantity. Tests such as:
AMH (Anti-Müllerian Hormone) Test: Measures ovarian reserve.
FSH & Estradiol Tests: Assess ovarian function and hormone levels.
Antral Follicle Count (AFC) via Ultrasound: Provides insights into egg supply.
Conclusion
Improving egg productivity and quality requires a holistic approach that includes a healthy diet, lifestyle adjustments, and, if needed, medical assistance. By adopting these strategies, you can enhance your fertility potential and increase your chances of a successful pregnancy. If you are planning for the future, consider consulting a fertility specialist for personalized guidance on preserving and optimizing your reproductive health.
