Last Update Date
21.10.2025

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In patients with low sperm viability, quantity, number and structural quality, microfluidic technology, also known as the "chip baby method", ensures that the best quality sperm cells are selected by competing with each other in a way similar to the natural environment in the uterus, and ICSI is defined in in vitro fertilization treatment. With the application, it is left into the egg cell by microinjection method.

In this method, sperm cells with the best structural form, genetics and physiology are selected without causing cell damage, since techniques such as centrifugation (settling), vortex (mixing with high vibration) or mixing with a pipette are not applied to the sperm cells, which can physically damage the sperm cells. In classical preparation methods, sperm cells are prepared in a shorter time without being subjected to manipulation by skipping processes such as washing, flotation, gradient (grading), centrifugation (precipitation at high speeds). Thus, the sperm cells with the best DNA quality and physiologically are selected by themselves, and the sperm cells that pass this pre-screening are again screened under the microscope and the sperm cells of excellent quality are used for microinjection.

The above-mentioned classical preparation methods cause sperm cells to undergo respiratory stress, known as oxidative stress, and it has been scientifically proven that this can also cause DNA damage in healthy sperm cells. Better quality embryos are tried to be obtained with sperm cells that have been proven to be of the best quality by scientific data, and thus embryos with the highest potential for implantation (attachment) and development are obtained. The average total mobility in suckling samples taken from male individuals with microchip technology increased by 1.7 times.
The sperm cells obtained by this method were found 3 times faster than the classical preparation methods, and the forward motile sperm cells increased 3.8 times.

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DOCUMENTS TO BE REQUESTED FROM THE PATIENT

1. Biometric photo (.pdf)

• Digitally scanned biometric photos of the patient and companion

2. Flight ticket reservation (.jpeg or .pdf)

3. Hotel reservation (.jpeg or .pdf)

• In case the patient stays in the hospital during the treatment; The document prepared on the letterhead of the health institution stating that the accommodation service will be provided by the hospital will be accepted.

4. Proof of income (.jpeg or .pdf) showing that he can cover the treatment costs

• Bank-approved bank statement document containing the last 6 months. If the patient does not have his own bank account, his spouse will be accepted (an official document showing that he is a spouse will be attached)

5. Colored and legible scanned images (.jpeg or .pdf) of the front and back of the passport

6. Document showing the compulsory health or travel insurance of the patient

7. Receipt showing that the treatment fee has been paid to the health institution in Turkey

• At least $ 500 (USD) must be deposited into the hospital account, and the patient's name, surname and passport number must be written as an explanation.

Note: The documents must be requested from the patient with color scanning.

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“Ovarian hyperstimulation syndrome”, also known as Ovarian Hyperstimulation Syndrome (OHSS), in the most basic way; It can be explained as a reaction to the hormones given to women for the development of the ovaries. During IVF treatment, women are given hormone drugs to stimulate and support egg development. When these hormone drugs stimulate the ovaries more than necessary, the syndrome of overstimulation of the ovaries occurs.


How Ovaries Stimulation Happens?

Ovarian hyperstimulation syndrome (OHSS) is an undesirable consequence of IVF treatment. Although the aim of IVF treatment is to develop a large number of eggs, OHSS may occur if more than a certain number of eggs develop.

Women with polycystic ovary syndrome are much more likely to have ovarian overstimulation syndrome. Excessive response to the drugs given to stimulate the ovaries prepares the ground for encountering this syndrome. During the stimulation of the ovaries, there is a fine line between stimulating the desired number of eggs and over-stimulating the ovaries. It is not always possible to determine this point clearly. When there is overstimulation, reducing the dose of ovarian stimulating drugs and not giving the drug for a day or more, if needed, can prevent the excessive rise of estrogen.


Symptoms of ovarian hyperstimulation syndrome can be mild, moderate or severe. These symptoms are;

-Increased ovarian size

- Abdominal pain, bloating, shortness of breath, decreased urination

-Fluid accumulation in the abdominal cavity

-Coagulation disorders

It can be seen as fluid collection in the chest cavity. It is extremely important to follow these situations closely and to get medical support when necessary.


How is Ovarian Overstimulation Syndrome Treated?

OHSS treatment is carried out to relieve the expectant mother, reduce ovarian activity and prevent complications. However, OHSS can be performed in two different ways as drug and surgical treatment. In mild cases, no additional treatment is required other than outpatient follow-up and severe physical activity restriction, and the patient can usually recover in 10-14 days. Moderate and severe cases may require hospitalization and treatment. In most cases, women who have had OHSS can continue IVF. It is still possible to become pregnant despite OHSS, but these symptoms may worsen if pregnancy occurs. In this case, the patient is followed closely under the supervision of a doctor.


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IVF treatment, which is preferred by couples who cannot conceive naturally and cannot have children, is a source of hope for couples who cannot have children due to the development of medicine and technology. IVF treatment is the fertilization of male and female reproductive cells outside the body under laboratory conditions. Currently, couples have a 95 percent chance of success with IVF treatments. IVF treatment is one of the most successful methods in the treatment of infertility, the cause of which is not clear, or which cannot be conceived in the most natural ways. If couples do not succeed in their first attempts at IVF treatments, they should not despair and stress immediately. Because there are no restrictions on IVF treatment.

How many times can IVF treatment be tried?

 

A study conducted on couples undergoing IVF treatment shows that the rate of achieving pregnancy in couples after the first three trials is 95 percent. In addition, no number can be given about the number of treatments in the remaining group. The experts are also 4. or 5. there is an opinion that the chances of IVF success in trials are slightly lower than in the first three trials. The success rate of IVF treatment does not depend on many attempts. Multiple factors, such as the age of the couples, obtaining a quality embryo, affect the success rate of IVF treatment at a critical point.


Is Success Achieved in the First Attempt in IVF?

The chances of pregnancy during the one-month treatment period with the insemination method or ovulation treatments are about 20% or slightly more than the chances of a healthy couple becoming pregnant in a month. These treatments can be tried 3 or 4 times until pregnancy is achieved, but most of the pregnancies are obtained in the first months of treatment. Continuing treatment for more than 4 years will not increase the chances of pregnancy, so you can switch to IVF treatment.


Currently, thanks to newly developed methods and applications, the success rate of in vitro fertilization treatment is gradually increasing, if success is not achieved at the first attempt, repeated attempts can be made. The chance of becoming pregnant in a month with IVF treatments varies depending on age, but on average it is up to 50-60%. Pregnancy rates can increase by more than 90% after 4 applications when more than one treatment is performed in a row. For this reason, the chances of becoming pregnant increase with the number of attempts in couples who do not have a specific problem.


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There are 2 treatment methods most commonly preferred by couples who want to have a baby but do not have a baby for various reasons. One of them is in vitro fertilization treatment and the other is insemination method. In our article, we will try to answer the most frequently asked questions about the vaccination method, what is insemination and how it is done.


What is insemination? 


If couples cannot get a pregnancy result after one year after unprotected sexual intercourse, infertility is diagnosed. Infertility can have many causes, depending on the woman and the man. Thanks to science and developing technology, there are now many treatment methods for infertility. One of these methods is the vaccination method. In its simplest form, the method of vaccination is to prepare the sperm in the laboratory and inoculate the woman's uterus at the time of ovulation to ensure fertilization. In order for the vaccination method to be performed, some tests must be done to make sure that there is no problem in the uterus of the expectant mother. In addition, at least one of the tubes of the expectant mother must be in working condition. The purpose of the vaccination method is to select the motile, normal sperm with a higher probability of fertilization and send them to the uterus of the expectant mother. Thus, it will be more likely to be fertilized with eggs and selected sperm supported by drugs or pills. 


How is insemination done?


Before the insemination method, the development of the egg is supported with pills or low-dose injections given to the expectant mother. During this process, the egg is tracked. When the eggs mature and reach certain sizes, a cracking needle is given and the eggs are cracked. Just at this time of cracking, the sperm prepared in the laboratory are transferred to the uterus. Thus, the most suitable time of ovulation is provided for the woman and the best sperm are transferred to the uterus at the right time. insemination is a natural method. Only sperms that will increase the probability of fertilization are carefully selected. From the sperms taken from the father-to-be, those that are of good quality, motile and washed in a certain number, that is, processed. As Hüma IVF Center team, we tried to give information about what is insemination and how it is done in our article. We hope it was useful. You can contact us via our website to get more detailed information about IVF treatment or to ask your questions.

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Parents who want to have children generally prefer the most common in vitro fertilization treatment. Before this treatment, both mother-to-be and father-to-be go through many tests. Father-to-be passed; The first of the tests to test for infertility or other problems is the sperm test, also known as the spermiogram test. What is the spermiogram test for the analysis of the sperm cell? How is spermiogram done? What do spermiogram test results mean? We will answer all these questions for you in detail below. We recommend that you continue reading our article to have detailed information about the sperm test.

 What is a test (spermiogram)?



Sperm test done to men; It is a test to determine sperm health, sperm count, and whether the sperm are moving correctly in the channels. As a result of the sperm test, if the sperm shape is normal and there is a sufficient number of sperm, it is concluded that your reproductive ability is high. However, in some cases, men may have low sperm count or the ability to reproduce despite having abnormal semen. That's why doctors order a second test for the accuracy of the results. If your results are normal in your first sperm test, you give the other test and if it is normal, these two normal tests show that you do not have an infertility problem. If there are different conditions, your doctor may order other tests.

If there is no semen or sperm as a result of the sperm test, this may indicate that your ducts are blocked. If this is the case, your doctor will plan different surgeries to open the channels.

Issues and Precautions to Consider While Giving Sperm Sample



There are important points to be considered before giving the sperm sample and while giving the sperm sample. Among the things to be considered before giving a sperm sample, we can count that "men should abstain from sexual intercourse for 3 days". Fasting for 3 to 5 days is sufficient. These numbers are important because if you fast for less than 3 days, the sperm count may be low as a result of the sperm test. For this reason, we can say that fasting between 3 and 5 days is sufficient. It is possible to list the issues to be considered while giving a sperm sample as follows;

 

· Storing the sample in a sterile environment: It is important to protect your sample from the outside environment for a healthy and accurate spermiogram test result. If a sterile environment is not provided, the test result may be inaccurate. Therefore, do not put your hands, especially sample containers, etc. It is important that you keep it as sterile as possible.

· Protecting the delivered sperm from heat: Another important point is to keep your sample away from extreme temperature changes after ejaculation. Because these extreme temperature changes negatively affect spermatozoa. Ideal temperatures for the sample cup should be between 20°C and 37°C.

· Sperm volume, amount: Volume is extremely important in the sperm test. Your sperm volume is expected to be at least 1.5 ml. The reason why you cannot reach the lower limit of 1.5 ml may be external discharge during ejaculation. It is important to be careful about this.

· Use of lubricating foreign substances during the sperm test: It is important not to use any lubricant during the sperm test because these substances seriously affect the sperm parameters. External factors with such an impact can lead to wrong conclusions.

How is the Sperm Test Done?



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



After the sperm test is given by the prospective fathers, it is examined in the laboratory environment. This examination takes approximately 1-2 hours and after the first hour, active results begin to be obtained. However, sometimes different situations can be encountered. For example, the test is given, but no sperm can be seen when looked at. In these cases, sperm are taken again and centrifuged. When faced with such a situation, the time may be extended. If there is no additional test to be done, the test results are immediately available in an average of 1-1.5 hours.

What Do Sperm Test Results Mean?



       





Sperm test results can be evaluated in many ways. Sperm analysis evaluates the sperm by analyzing it from various aspects. We can list these analyzes as follows:

· Sperm count and density:

Sperm count describes the number of sperm in 1 ml of semen. The World Health Organization advocates that a normal sperm count should be at least 15 million per ml or at least 39 million per sample. Having fewer sperm than these numbers indicates a low sperm count.

· Sperm morphology:

Non-abnormal sperm have a long tail and oval head. Morphology refers to the size and shape of the sperm a person has. Sperm that do not have a normal size or are weak in shape have difficulty reaching the egg and fertilization.

· Sperm motility:

The ability of sperm to move efficiently is one of the most important factors for fertilization.

· PH level of sperm:

When the pH level is too high or too low, it can affect the health of sperm and its ability to pass through the female reproductive tract.

Apart from these, sperm health is examined by looking at many factors such as semen volume, liquefaction, and seminal fructose levels while performing the sperm test. After examining all factors in detail, the results are examined and reported to the patient.

What is the Sperm Test Result of a Healthy Individual?



Low sperm count can have many different causes. The first reason is smoking addiction. Smoking addiction is one of the important factors that reduce the sperm count. In addition to smoking, alcohol and drug addiction also affect sperm count. Sperm count can also be adversely affected when there is a deficiency in hormones, depending on the clogged ducts.

Hormones are one of the important factors for reproduction on their own. Since the deficiency in reproductive hormones directly affects sperm production, it increases the possibility of encountering problems in reproduction. Apart from these, mistakes made by couples who want to have children also affect the sperm count. Using natural products unconsciously and continuing to use them uncontrollably, without knowing the limit, does harm to the person instead of providing benefits. Long-term treatment and drugs used during the treatment also affect the sperm count.

IMSI in Sperm Selection



The IMSI (Intracytoplasmic Morpholgically Selected Sperm Injection) method is the magnification and examination of even the smallest cells using special microscopes. In the past, in the microinjection procedures applied in IVF treatments, living sperm cells could be enlarged up to 400 times. However, with IMSI, sperm can now be enlarged between 6000 and 8000 times. It is possible to examine and detect in detail the disorders called "vacuoles" that indicate the intracellular structures of the sperm and their genetic damage.

The IMSI technique is an extremely useful method. Selected sperm injection; It allows advanced morphological analysis of sperm without damaging the living sperm cell. Sperm with the highest fertilization ability are selected and a high chance of fertilization between 20% and 40% can be obtained with the applied microinjection application.

Precautions to be Considered for Sperm Quality



Couples who want to have children should pay attention to egg and sperm health and be careful in this regard. There are many factors that affect sperm quality, such as those that affect egg quality. One of these factors is undoubtedly a healthy diet. A healthy diet is extremely important for every organ in the body, of course also in sperm health.

In addition, exercise is very important in making you more vigorous and increasing your body's stamina and activity. Regular exercise will make you recover in a short time and will positively affect both your mental and physical health. Alcohol and smoking are substances that affect reproductive cells and should be avoided. This is a proven fact as a result of research. If we gather all these under one title, we can say that one should take care of his own health. Nutrition, avoiding alcohol, smoking, exercising regularly will first affect your health and therefore your sperm quality.

This process, which is sensitive and special for couples who want to have a child, is extremely important for them. In this process, prospective parents experience excitement on the one hand and a lot of stress on the other. Hüma IVF Center, which understands the emotions experienced best and does not spare its support by being by their side throughout the process, is always ready to accompany you.

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Serum Intralipid Therapy is a treatment used specifically to strengthen the immune system. The immune system plays a big role in the repeated IVF failures and recurrent miscarriages seen in some women. For this purpose, intralipid serum therapy is also used. This is a type of treatment that is started prior to IVF treatment and is applied once a week or every two weeks until the baby's heartbeat is heard, if deemed necessary after pregnancy is achieved. Now let's take a closer look at intralipid serum treatment together ...

What is Intralipid Serum Therapy?

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Intralipid serum therapy is a form of treatment that starts on the day of the transfer and continues throughout the process. Intralipid whey contains fat molecules and soy protein, which strengthens the immune system. The immune system is extremely important for a healthy pregnancy and its continuation. Because half of the child belongs to the father, the mother's body does not reject it. In vitro fertilization failure also occurs in case of rejection, but intralipid therapy can prevent this failure.

For whom and how is intralipid serum treatment applied?

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Intralipid Serum Therapy is an immune-boosting treatment that is commonly used in women with recurrent miscarriage problems and recurrent IVF failures. As a result of studies, it was found that treatment with intralipid serum does not have side effects. Only women can be allergic to some substances in the serum of intralipid, in which case this should be determined in advance. These substances are a number of special ingredients such as glycerin, egg phospholipids. It is preliminarily checked whether the patient is allergic to these substances. If the patient has an allergy, treatment is not applied.

Intralipid whey treatment is carried out with a preparation containing emulsified oil prepared with a special concentration, which takes approximately 45 minutes. Fatty sera are administered to the patient intravenously.

In this article: what is serum intralipid therapy, who is this treatment for, how is intralipid therapy used? We have answered all these questions for you. If you want to get more detailed information about this, we recommend that you visit the website of the HUMA center.

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What is infertility, what are its symptoms, what kind of treatment method is applied?



Infertility, as it is called in the medical literature, is one of the most important health problems affecting millions of people around the world. In addition to being a health problem that can be seen in women and men, today the number of couples who cannot have children is quite high. According to researches, 10-15% of couples who have unprotected sexual intercourse for a year cannot have a child.

In our article, about infertility, one of the most important health problems in the world; We will try to give short answers about what is infertility, what are the symptoms of infertility and how to apply the treatment method.




What is infertility?


According to the definition of the World Health Organization, infertility; “Failure to conceive within one year of a sexually active couple who had unprotected intercourse without using contraception.” is the status. In other words, in order to be able to talk about infertility exactly, couples must have unprotected intercourse for one year and be unable to conceive. Infertility is one of the important health problems affecting 25% of the world population. In the researches, it can be seen depending on the woman or the man.

What are the symptoms of infertility?

The most important sign of infertility for both men and women is the inability to get pregnant despite having unprotected sexual intercourse for one year. However, some symptoms seen in men and women can be seen as a sign of infertility and an examination may be required accordingly.


 infertility in women;


- Imbalances in the menstrual cycle can be considered as a symptom. If you have periods longer than 35 days or shorter than 21 days, you should definitely see a specialist.

- If you are in your 30s and younger, it is expected to get pregnant within 1 year.

- If you are in your 35s and 40s, pregnancy is expected within 6 months. If pregnancy does not occur within 6 months, it is useful to see a doctor.


Infertility in men;


- Sexual dysfunctions are considered a sign of infertility. Example; impotence, ejaculation, such as strain.

- Pain, swelling or a lump in the testicle area during sexual intercourse may also be a sign of infertility.

- Infertility in men can often be caused by hormonal disorders.

Although all these symptoms are not exactly the cause of infertility, they are among the factors affecting it and may be symptoms of infertility.



What kind of treatment method is applied in infertility?







There can be many different reasons for the occurrence of infertility. Therefore, first of all, the causes of infertility are investigated. Different treatment methods are tried according to the detected cause. Some of the treatment methods applied are as follows;

- IVF Treatment

- Vaccination

- Microinjection

In vitro fertilization is one of the most well-known and most preferred and effective treatment methods among other treatment methods.

As Hüma IVF Center team, we tried to give information about what is infertility, what are its symptoms and what kind of treatment method is applied in our article. We hope it was useful. You can contact us via our website to get more detailed information about infertility or to ask your questions.

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Ovarian reserve, known as the ovary, is a term used to determine the fertilization ability of the ovary to provide egg cells and to determine the probability of a successful pregnancy. With the advancing age of the expectant mother, the number of egg cells obtained from the follicles for pregnancy decreases. decreased ovarian reserve (AMH); It is a condition in which the ovaries begin to lose their normal production capabilities, reducing fertility. Decreased ovarian reserve reduces women's chances of conceiving spontaneously or with treatment. However, it is aimed to minimize the effects of this situation with various methods. The main causes of decreased ovarian reserve can be listed as follows:

· Smoking,

Chronic diseases,

 Coffee consumption

  Age of the expectant mother,

Genetic abnormalities (X chromosome abnormalities)

Various treatments (such as radiation for cancer)

· Having undergone ovarian surgery.

You can continue reading our article for reduced ovarian reserve and all its details.






How to Identify Decreased Ovarian Reserve?



Decreased ovarian reserve is determined by examining the hormone tests to be performed on the 2nd or 3rd day of the menstrual period of the expectant mother. FSH hormone gives information about the status of ovarian reserves. If the FSH value is higher than 10, it indicates decreased ovarian capacity.

The best indication of the capacity of the ovaries is the vaginal ultrasound. Existing and developing egg structures can be easily detected here. If there are less than six egg structures in the total ovaries, decreased ovarian reserve may be in question.

In summary, decreased ovarian reserve; It can be understood by clinical evaluation of the person, vaginal ultrasound, measurement of AMH hormone and FSH hormone in the blood.



Can a Woman with a Decreased Ovarian Reserve Get Pregnant?



Existing studies show that women with reduced ovarian reserve can become pregnant both spontaneously and with IVF treatment. Although it has been shown that high serum FSH levels in women are associated with low pregnancy rates, it is not sufficient to make a decision based on this alone. Egg cells also regulate their size under the influence of genetic factors. The speed of the aging process of the ovaries varies greatly among women, except for the age factor. In addition to the successful results of endocrine tests and imaging methods in the numerical evaluation of ovarian reserve, their values ​​in determining the chance of pregnancy remain at a limited level.

The chance of conceiving of a woman who is determined to have decreased ovarian reserve with ovarian reserve tests and clinical evaluations by specialist physicians can be increased by applying appropriate ovulation treatment protocols. Patients with reduced ovarian reserve can become mothers with different techniques today. In order to determine these methods, it is important to plan and apply special treatment methods suitable for patients by considering various factors.



How Is Decreased Ovarian Reserve Treated?



Currently, there is no treatment for decreased ovarian reserve that prevents or slows down ovarian aging. In addition, lifestyle changes have an extremely important role in preventing premature aging of the ovaries and in order to ensure the healthy continuation of egg quality, that is, to increase egg reserve and quality. These;

· Eating a balanced and healthy diet,

Doing regular exercise,

Quality and adequate sleep,

Avoiding chemicals, high glycemic index and fast food style foods,

Not to use substances such as cigarettes and alcohol,

· Using antioxidant drugs under the control of a physician.

 

 

If you have decreased ovarian reserve and want to have a child according to your required tests and vaginal ultrasound results, it is extremely important to seek in vitro fertilization treatment in the presence of a specialist doctor, without wasting time.

As Hüma IVF Center, we choose the most appropriate treatment method for you, apply it and continue to serve.

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Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.


What is blastocyst transfer?



Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.


What are the advantages of blastocyst transfer?



Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;

The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,

Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,

The chance to observe the embryo development more clearly and healthily,

Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,

· Allowing different methods to examine embryo viability.



What is the risk of blastocyst transfer?



The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.


Who is blastocyst transfer suitable for?



Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.

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Recently, it has been revealed that egg quality obtained from patients with low reserve is lower and genetic problems in the embryo are higher. In this direction, it is aimed to create fewer but better quality embryos by obtaining higher quality eggs with less drugs. Mini IVF appears as a simplified in vitro fertilization practice, unlike the known in vitro fertilization practices performed with daily injections and high-dose drug use. Especially in patients with a low number of eggs or in advanced age, the success rates are higher than conventional treatments. What is mini IVF, who is it applied to and what are the drugs used in its treatment? You can continue reading our article for questions and all the details.


What is mini IVF?



Mini IVF is an in vitro fertilization application that enables the development of fewer but higher quality eggs by using lower doses of drugs. Eggs developed with this method are taken and fertilization is performed by applying the microinjection technique. Embryos formed after fertilization are transferred to the patient, assuming that the probability of attachment is higher.

In addition to the advantages such as less drug use, less cost and less time spent with mini IVF treatment, high success rates can be obtained in patients with a low number of eggs and advancing age.



Who is mini IVF applied to?



In cases where pregnancy does not occur naturally;

Those who want to use hormone drugs less,

At risk of developing OHSS (overstimulation of the ovaries),

Concerned about the daily injection process in IVF treatment,

Those who have problems in the fallopian tubes and are younger than 35 years old,

Having low egg reserve that cannot be increased with treatment,

Looking for a more economical solution than conventional treatment,

People who have tried many times in vitro fertilization but have not achieved a result, and

Mini IVF treatment can be applied to women who want to reduce the possibility of multiple pregnancy.

However, a treatment plan should be made by a specialist by listening to the patient's history of the disease, analyzing their expectations and performing health checks in detail.



What are the drugs used in mini IVF treatment?



Mini IVF treatment is a type of in vitro fertilization that uses little or no medication to increase and develop the number of eggs. In standard IVF treatments, hormone injections are made for 8-10 days to reproduce eggs, while these drugs are not used in the Mini IVF method. Oral tablets and very low dose hormone injections are used instead. With Mini IVF, which is a natural in vitro fertilization method, it is ensured that the highest quality eggs are produced by using the least amount of medication.

Mini IVF method is aimed to obtain better quality eggs with the use of low doses of drugs. At this point, it is possible to determine your treatment plan by consulting your doctor. You can visit our website for more information.

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How to Improve Egg Productivity & Quality

Fertility is a crucial aspect of reproductive health, and for women, egg productivity and quality play a vital role in conception. The number and quality of eggs naturally decline with age, but various lifestyle changes, diet improvements, and medical interventions can help maintain and enhance ovarian health. Whether you are planning for pregnancy now or preserving fertility for the future, here are some effective ways to boost egg productivity and quality.

1. Maintain a Balanced and Nutrient-Rich Diet

What you eat directly impacts your reproductive health. A fertility-friendly diet should include:

  • Antioxidants: Found in berries, nuts, and leafy greens, antioxidants help protect eggs from oxidative stress.

  • Healthy Fats: Avocados, olive oil, and nuts support hormonal balance and egg cell membrane integrity.

  • Protein Sources: Include lean meats, fish, eggs, and plant-based proteins like beans and lentils to promote healthy egg development.

  • Folic Acid & B Vitamins: Essential for cell division and DNA synthesis. Found in leafy greens, citrus fruits, and fortified grains.

  • Omega-3 Fatty Acids: Found in salmon, flaxseeds, and walnuts, they enhance egg quality and overall reproductive health.

2. Stay Hydrated

Drinking enough water is essential for circulation and nutrient transport to the ovaries. Dehydration can negatively affect egg development and hormone production.

3. Maintain a Healthy Weight

Being overweight or underweight can disrupt hormonal balance and ovulation. Maintaining a BMI within a healthy range supports regular ovulation and egg maturation.

4. Reduce Stress Levels

Chronic stress increases cortisol levels, which can interfere with reproductive hormones and egg development. Stress management techniques include:

  • Meditation & Yoga: Help regulate stress hormones and improve blood flow to reproductive organs.

  • Regular Exercise: Moderate physical activity boosts circulation and hormone regulation.

  • Adequate Sleep: 7-9 hours of quality sleep each night supports hormone balance and overall health.

5. Avoid Toxins and Harmful Substances

  • Reduce Caffeine & Alcohol: Excessive intake can negatively affect fertility.

  • Quit Smoking: Smoking accelerates ovarian aging and reduces egg quality.

  • Limit Exposure to Environmental Toxins: Pesticides, plastics (BPA), and heavy metals can harm egg health. Opt for organic foods and use BPA-free products.

6. Take Fertility-Boosting Supplements

Certain vitamins and supplements can enhance egg quality:

  • Coenzyme Q10 (CoQ10): Improves egg cell energy and mitochondrial function.

  • Vitamin D: Supports ovarian function and hormonal balance.

  • Zinc & Selenium: Help protect eggs from oxidative stress and improve overall reproductive health.

  • DHEA (Dehydroepiandrosterone): A precursor hormone that can help improve ovarian reserve in some cases (consult a doctor before use).

7. Consider Medical Interventions if Necessary

If you are struggling with fertility issues, consult a specialist who may recommend:

  • Hormonal Therapy: Helps regulate ovulation and improve egg development.

  • Ovulation Induction Medications: Clomiphene citrate or Letrozole can stimulate egg production.

  • IVF (In Vitro Fertilization): If natural conception is difficult, IVF can retrieve multiple eggs for fertilization.

  • PRP (Platelet-Rich Plasma) Therapy: An emerging treatment that may help rejuvenate ovarian function.

8. Monitor Your Ovarian Reserve

Regular fertility check-ups can help assess egg quality and quantity. Tests such as:

  • AMH (Anti-Müllerian Hormone) Test: Measures ovarian reserve.

  • FSH & Estradiol Tests: Assess ovarian function and hormone levels.

  • Antral Follicle Count (AFC) via Ultrasound: Provides insights into egg supply.

Conclusion

Improving egg productivity and quality requires a holistic approach that includes a healthy diet, lifestyle adjustments, and, if needed, medical assistance. By adopting these strategies, you can enhance your fertility potential and increase your chances of a successful pregnancy. If you are planning for the future, consider consulting a fertility specialist for personalized guidance on preserving and optimizing your reproductive health.

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