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WHAT IS INTRALPID SERUM TREATMENT? WHO IS APPLIED?

Intralipid serum therapy emerges as a form of treatment applied to women who want to become pregnant but cannot achieve this goal as a result of recurrent IVF failures. It is extremely important that the immune system is strong during IVF treatment. Intralipid serum therapy is a method used at this point to strengthen the immune system.

Intralipid serum treatment is started to be applied to women who want to become pregnant before starting IVF treatment. What are the details of intralipid treatment? Who is intralipid serum therapy applied to? How is intralipid serum therapy applied? Now we will be giving answers to all these questions for you below.

What is Intralipid Therapy?

Intralipid serum therapy is a treatment for women who want to become mothers. Intralipid serum is a treatment method that starts on the day of transfer and continues throughout the process in IVF treatment. Intralipid serum contains many important proteins and molecules for the immune system. Thanks to this serum, it is aimed to keep the immune system of the expectant mother strong during pregnancy by supporting the immune system.

To Whom Is Intralipid Serum Treatment Applied?

Intralipid serum therapy is a treatment for women who want to become mothers, but only for those who have experienced miscarriage problems or who have experienced IVF failures. The purpose of this treatment is to ensure that the immunity of the expectant mother remains strong throughout the pregnancy process.

As a result of the information obtained, it has been proven that intralipid serum therapy does not have any side effects. However, some women may be allergic to the substances in the intralipid serum. At this point, good research should be done before starting the treatment and if there is no allergic condition, treatment should be applied.

How is Intralipid Serum Treatment Applied?

Parents who want to have a child can resort to many ways for pregnancy to occur. In vitro fertilization, which has been very popular recently, has been determined as the most successful assisted reproductive method. If there are recurrent failures as a result of IVF treatment, this problem can be eliminated with intralipid serum treatment. Intralipid serum therapy is an extremely effective and successful form of treatment.

Intralipid serum treatment is administered to the expectant mother by intravenous route, with a preparation containing emulsified oil, prepared with a special concentration, which takes approximately 45 minutes. In other words, the patient's immune system is supported by giving oily serums intravenously.

In this article, we have given detailed explanations about inralipid serum therapy and that parents can receive intralipid serum treatment in cases where pregnancy does not occur due to some reasons. If you want to have more detailed information on this subject, you can visit https://www.humatupbebek.com/.

Serum Intralipid Therapy is a treatment used specifically to strengthen the immune system. The immune system plays a big role in the repeated IVF failures and recurrent miscarriages seen in some women. For this purpose, intralipid serum therapy is also used. This is a type of treatment that is started prior to IVF treatment and is applied once a week or every two weeks until the baby's heartbeat is heard, if deemed necessary after pregnancy is achieved. Now let's take a closer look at intralipid serum treatment together ...

What is Intralipid Serum Therapy?

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Intralipid serum therapy is a form of treatment that starts on the day of the transfer and continues throughout the process. Intralipid whey contains fat molecules and soy protein, which strengthens the immune system. The immune system is extremely important for a healthy pregnancy and its continuation. Because half of the child belongs to the father, the mother's body does not reject it. In vitro fertilization failure also occurs in case of rejection, but intralipid therapy can prevent this failure.

For whom and how is intralipid serum treatment applied?

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Intralipid Serum Therapy is an immune-boosting treatment that is commonly used in women with recurrent miscarriage problems and recurrent IVF failures. As a result of studies, it was found that treatment with intralipid serum does not have side effects. Only women can be allergic to some substances in the serum of intralipid, in which case this should be determined in advance. These substances are a number of special ingredients such as glycerin, egg phospholipids. It is preliminarily checked whether the patient is allergic to these substances. If the patient has an allergy, treatment is not applied.

Intralipid whey treatment is carried out with a preparation containing emulsified oil prepared with a special concentration, which takes approximately 45 minutes. Fatty sera are administered to the patient intravenously.

In this article: what is serum intralipid therapy, who is this treatment for, how is intralipid therapy used? We have answered all these questions for you. If you want to get more detailed information about this, we recommend that you visit the website of the HUMA center.

Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.

What is blastocyst transfer?

Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.

What are the advantages of blastocyst transfer?

Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;

The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,

Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,

The chance to observe the embryo development more clearly and healthily,

Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,

· Allowing different methods to examine embryo viability.

What is the risk of blastocyst transfer?

The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.

Who is blastocyst transfer suitable for?

Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.

IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.

What is Comprehensive Chromosome Screening (NGS)?

It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.

Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.

What are the Features of the NGS Technique?

Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.

What Genetic Defects Can Be Detected with NGS-Based PGS?

Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.

To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.

Who are the Groups of Patients Who Can Be Administered NGS?

The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;

· In cases of repeated miscarriage,

· in expectant mothers over the age of 38,

· In severe male infertility,

* In cases of infertility, the cause of which is unknown,

· It is applied in cycles of continuous self-recurring treatment failures.

The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.

What are the Advantages of Preimplantastone Genetic Screening with NGS?

NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.

Does NGS Damage the Embryo?

IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.

Does Pregnancy Always Occur With a Smoothly Detected Embryo?

After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;

· Women's age

· The amount of ovarian reserve of the woman

* Sperm quality

· Embryo quality

· Ensuring a proper intrauterine environment

· The presence of hydrosalpinx

· Conditions encountered during embryo transfer

it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.

Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.

In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.

How Many Days Do NGS Results Come Out?

The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.

What are the NGS Test Prices?

The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.

In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.