Last Update Date
21.10.2025

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About Hüma International Hospital

Founded in March 2004 as Kayseri’s first dedicated Women’s Health Center, Hüma has continually expanded its scope of medical services to meet the evolving needs of its patients. In 2006, the institution grew into a full-fledged Gynecology and Obstetrics Hospital, broadening its reach and enhancing its capacity to provide specialized care for women. The hospital further solidified its position as a leader in women’s healthcare by establishing a state-of-the-art IVF Center in 2014, offering cutting-edge fertility treatments backed by the latest advancements in reproductive medicine.

Today, Hüma International Hospital has become a trusted name in gynecology, obstetrics, fertility, and urogynecology, providing evidence-based, modern, and patient-centered healthcare. With a team of highly experienced physicians, nurses, and medical specialists, Hüma is committed to delivering superior healthcare services through advanced medical technology and a compassionate approach.

International Patient Services

Understanding the unique needs of international patients, Hüma International Hospital has established a comprehensive International Patient Services Center, designed as a “one-stop” service hub. This center is dedicated to ensuring a seamless and comfortable healthcare experience for patients traveling from abroad. From the initial inquiry to post-treatment follow-up and the patient’s safe return home, the International Patient Services Team provides personalized support at every step of the journey.

Why Choose Hüma International Hospital?

  • Highly Experienced Medical Team: Renowned physicians, nurses, and fertility specialists with extensive expertise.

  • Exceptional Success Rates: Proven track record in IVF, gynecology, and obstetrics.

  • Personalized Treatment Plans: Tailored medical approaches designed to meet each patient’s specific needs.

  • Uncompromising Patient Satisfaction: A commitment to excellence in healthcare and patient care.

  • Affordable & Transparent Pricing: Cost-effective treatments with no hidden fees, offering Europe’s most competitive pricing in fertility and gynecological care.

  • Best Price Guarantee: High-quality treatments at the most affordable rates.

At Hüma International Hospital, we prioritize medical excellence, patient well-being, and ethical healthcare practices, ensuring that every patient receives the highest standard of treatment in a safe and comfortable environment

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Every woman wants to have beautiful, clean and smooth skin. Laser epilation, which has facilitated the work of not only women but also men in recent years, is an extremely effective method applied to permanently remove unwanted hair follicles and unwanted hair. The fact that it has the quality of use in all seasons and that it does not have any roughness has also increased its degree of effectiveness. The most distinctive feature of the ice laser is that it offers many methods as a whole and gives the expected results quickly.

The Ice laser epilation device, which we offer in our hospital, is a laser epilation method that is applied every season with an extremely low level of pain and technological systems are used. Thanks to the hair follicles that can be destroyed by laser, you will have clearly observed that your hair growth or hair growth problems have decreased visibly. Laser epilation is an effective and safe treatment to permanently get rid of unwanted hair. An important point to note in laser epilation applications that both men and women can apply is that the laser procedure is performed by trained specialists in a hospital environment under the control of a doctor. People with darker skin tones may experience hyperpigmentation and scarring, while people with lighter skin tones may experience temporary redness and swelling. You can have laser epilation in our hospital accompanied by a specialist doctor and esthetician.
If you are looking for a hassle-free solution for your epilation needs, the Ice laser epilation technique, which you can safely choose for four seasons, may be the perfect option for you.

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PREIMPLANTATION GENETIC DIAGNOSIS
In recent years, developments in genetics allow genetic analysis to be carried out on embryos developed in vitro by in vitro fertilization  ethods and the placement of selected healthy embryos in the uterus of the mother before pregnancy occurs. This method is called pre- regnancy genetic diagnosis (Preimplantation Genetic Diagnosis-PGD).
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One of the most important application areas of the PGT technique embryos that do not have a genetic disease but may not have a genetic disorder in their chromosomes.
These disorders are more common in women of advanced age (35 years and older). This situation may result in infertility as it both reduces the chance of attachment of the embryo (implantation) and may cause unwanted abortions. As a matter of fact, 40 out of every 100 pregnancies in women aged 39 and over have problems that occur due to a numerical chromosomal disorder
 
The aim of PGD is to increase implantation rates, reduce spontaneous abortions and increase healthy baby birth rates by selecting hromosomally normal embryos. Indeed, the miscarriage rate, which can reach up to 23 percent in normal pregnancy due to chromosomal disorders, may decrease to 9 percent after PGD.
 
Pre-pregnancy genetic diagnosis is performed by taking 1 or 2 cells from embryos developed as a result of fertilization of egg and sperm cells obtained from mother and father candidates in laboratory environment. Special methods called Fluorescence In Situ Hybridization (FISH), Microarray-based comparative genomic hybridization (aCGH) or Polymerase Chain Reaction (PCR) are used for genetic diagnosis. Diagnosis of numerical chromosomal disorders such as monosomy or trisomy (Down syndrome and other trisomies) and single gene diseases (such as hemophilia, Mediterranean anemia, cystic fibrosis, muscular dystrophies) in the baby to be born is possible with PGD. Thus, healthy babies are born by transferring disease-free, healthy embryos to the expectant mother.
 
DIAGNOSIS BEFORE PREGNANCY
 
  • In couples with a genetic or hereditary disease carrier,
  • In couples who have a child or children with a previous genetic disease,
  • For the purpose of HLA genotyping (tissue typing),
  • In the identification of diseases showing genetic predisposition (tendency)
  • Women in the advanced age group (37 years and over) who have been accepted for assisted reproductive techniques,
  • In couples with recurrent early pregnancy miscarriages,
  • In couples who could not achieve pregnancy with assisted reproductive techniques despite multiple applications or who lost their pregnancy due to miscarriage,
  • It is applied in cases of chromosomal disorders or genetic diseases associated with severe male infertility.
 
HOW IS THE PGT TEST DONE?
 
  • Whether the patient is suitable for PGD is evaluated by the reproductive health specialist, genetic counselor and the doctor of the related disease.
  • The couple is prepared for the IVF procedure.
  • The egg taken from the mother is fertilized in the laboratory with the sperm taken from the father.
  • 1-2 blastomere cells are removed from the obtained embryo by biopsy by embryologists
  • Cells obtained by biopsy are prepared and tested according to the method to be applied.
  • Embryos with genetic diseases or chromosomal disorders are selected and discarded and healthy embryos are transferred to the mothers womb.

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In patients with low sperm viability, quantity, number and structural quality, microfluidic technology, also known as the "chip baby method", ensures that the best quality sperm cells are selected by competing with each other in a way similar to the natural environment in the uterus, and ICSI is defined in in vitro fertilization treatment. With the application, it is left into the egg cell by microinjection method.

In this method, sperm cells with the best structural form, genetics and physiology are selected without causing cell damage, since techniques such as centrifugation (settling), vortex (mixing with high vibration) or mixing with a pipette are not applied to the sperm cells, which can physically damage the sperm cells. In classical preparation methods, sperm cells are prepared in a shorter time without being subjected to manipulation by skipping processes such as washing, flotation, gradient (grading), centrifugation (precipitation at high speeds). Thus, the sperm cells with the best DNA quality and physiologically are selected by themselves, and the sperm cells that pass this pre-screening are again screened under the microscope and the sperm cells of excellent quality are used for microinjection.

The above-mentioned classical preparation methods cause sperm cells to undergo respiratory stress, known as oxidative stress, and it has been scientifically proven that this can also cause DNA damage in healthy sperm cells. Better quality embryos are tried to be obtained with sperm cells that have been proven to be of the best quality by scientific data, and thus embryos with the highest potential for implantation (attachment) and development are obtained. The average total mobility in suckling samples taken from male individuals with microchip technology increased by 1.7 times.
The sperm cells obtained by this method were found 3 times faster than the classical preparation methods, and the forward motile sperm cells increased 3.8 times.

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As couples who want to become parents cannot become parents with natural methods, couples resort to some treatments. In vitro fertilization is the first treatment method. And IVF treatment is a very advanced and effective treatment method. Some applications in IVF treatment are important for the positive outcome of the treatment. Embryo glue application, which is one of the important application methods, is a very successful application. Embryo glue is one of the applications without any known risk. As a result of the studies, it was concluded that it did not increase the risk of miscarriage or pregnancy complications. Now we will provide you with detailed information about embryo glue. We wish you pleasant reading.

What is Embryo Adhesive?



Embryo glue, a method used in IVF treatments, is a kind of liquid embryo culture medium enriched with a substance called hyaluronan, in which embryos are left before transfer to the uterus of the expectant mother.

Hyaluronan is a natural carbohydrate found in all tissues in the body. The embryo needs an environment rich in carbohydrates, amino acids and protein in order to develop healthily inside. In addition, embryo glue is also called embryo glue because it reduces the ability of the embryo to move in the uterus.

How and Who Is Embryo Adhesive Used?



Embryo adhesive application is done as follows:

After the embryos are developed in the laboratory for 3-5 days, the most suitable one for embryo transfer is selected.

· The most suitable embryos selected for transfer are taken into the embryo glue.

· Embryos are kept in this environment for about 30 minutes.

· After standing, the embryos are taken from the culture dish and drawn into the catheter (a thin tube).

· The catheter is then passed through the cervix under ultrasound guidance and the embryos are transferred to the uterus.

In expectant mothers who have repeated in vitro fertilization failure using the embryo glue method,

It is used in couples who want to have children over the age of 35, when the quality of the embryo depending on the egg or sperm is not very good.

Is the Success Rate High in Embryo Bonding?



Embryo adhesive is one of the most frequently used applications for the last 10 years in order to increase the chance of success in IVF treatment. Experts were unsure about the effectiveness of embryo glue at first. However, in recent years, the effectiveness of embryo glue has been observed as a result of scientific research. Today, embryo glue is applied by various IVF centers. Hüma IVF Center is one of these centers.

The high concentration of hyaluronan concentrates the embryo glue similar to the tissue of the fluids in the womb, so that better mixing of these fluids minimizes the mobility of the embryo. In addition, hyaluronan acts as a bridge between the embryo and the inner wall of the uterus by binding to the inner wall of the uterus and the molecules on the surface of the embryo. In this way, it helps the embryo to attach to the uterus.

We aimed to give you information on this subject by considering the embryo glue method. We talked about how this method is applied and its success rate.

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IVF treatment, which is one of the methods of treatment that helps reproduction, begins with the collection of eggs from the expectant mother and the removal of sperm cells from the expectant father. The embryo, which appeared after the fertilization was carried out in the laboratory environment, is placed in the womb of the expectant mother. From this point on, pregnancy continues like a pregnancy acquired by natural means.







When should couples who cannot have children turn to IVF treatment?



A woman under the age of 35 who does not have any diseases that can prevent her from becoming pregnant should definitely be examined if she cannot conceive despite having unprotected and regular sexual intercourse for 1 year and seek treatment if deemed necessary. Women who are over the age of 35 or who have previously had any problems affecting conception should only try for 6 months.







How is IVF Performed? What are the Necessary Conditions?



In vitro fertilization can be defined as the process of placing the healthiest embryo in the womb obtained as a result of fertilization of eggs collected from the expectant mother with the sperm of the expectant father in the laboratory environment. Before starting IVF treatment, the reproductive abilities of both a man and a woman are evaluated. Then hormone therapy is started to allow the expectant mother's eggs to enter the maturation process. Then, a cracking needle is made and the eggs are released from the follicles. During the egg collection process, the ripening eggs of the expectant mother are collected with the help of transvaginal ultrasound. At this time, sperm cells are taken from the expectant father. 









Fertilization is achieved by means of reproductive cells that are brought together in a laboratory environment dec The healthiest of the embryos that occur, or in other words, the best IVF, is transferred to the expectant mother's uterus accompanied by ultrasound. After about half an hour after this procedure, the couple is sent home. In some cases, more than one embryo needs to be transferred to the mother's womb.

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Parents who want to have children generally prefer the most common in vitro fertilization treatment. Before this treatment, both mother-to-be and father-to-be go through many tests. Father-to-be passed; The first of the tests to test for infertility or other problems is the sperm test, also known as the spermiogram test. What is the spermiogram test for the analysis of the sperm cell? How is spermiogram done? What do spermiogram test results mean? We will answer all these questions for you in detail below. We recommend that you continue reading our article to have detailed information about the sperm test.

 What is a test (spermiogram)?



Sperm test done to men; It is a test to determine sperm health, sperm count, and whether the sperm are moving correctly in the channels. As a result of the sperm test, if the sperm shape is normal and there is a sufficient number of sperm, it is concluded that your reproductive ability is high. However, in some cases, men may have low sperm count or the ability to reproduce despite having abnormal semen. That's why doctors order a second test for the accuracy of the results. If your results are normal in your first sperm test, you give the other test and if it is normal, these two normal tests show that you do not have an infertility problem. If there are different conditions, your doctor may order other tests.

If there is no semen or sperm as a result of the sperm test, this may indicate that your ducts are blocked. If this is the case, your doctor will plan different surgeries to open the channels.

Issues and Precautions to Consider While Giving Sperm Sample



There are important points to be considered before giving the sperm sample and while giving the sperm sample. Among the things to be considered before giving a sperm sample, we can count that "men should abstain from sexual intercourse for 3 days". Fasting for 3 to 5 days is sufficient. These numbers are important because if you fast for less than 3 days, the sperm count may be low as a result of the sperm test. For this reason, we can say that fasting between 3 and 5 days is sufficient. It is possible to list the issues to be considered while giving a sperm sample as follows;

 

· Storing the sample in a sterile environment: It is important to protect your sample from the outside environment for a healthy and accurate spermiogram test result. If a sterile environment is not provided, the test result may be inaccurate. Therefore, do not put your hands, especially sample containers, etc. It is important that you keep it as sterile as possible.

· Protecting the delivered sperm from heat: Another important point is to keep your sample away from extreme temperature changes after ejaculation. Because these extreme temperature changes negatively affect spermatozoa. Ideal temperatures for the sample cup should be between 20°C and 37°C.

· Sperm volume, amount: Volume is extremely important in the sperm test. Your sperm volume is expected to be at least 1.5 ml. The reason why you cannot reach the lower limit of 1.5 ml may be external discharge during ejaculation. It is important to be careful about this.

· Use of lubricating foreign substances during the sperm test: It is important not to use any lubricant during the sperm test because these substances seriously affect the sperm parameters. External factors with such an impact can lead to wrong conclusions.

How is the Sperm Test Done?



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



For the sperm test, you must first be at the IVF center or hospital. There are rooms specially prepared for men in hospitals or IVF centers. In these rooms, men give their sperm in a special container. For the effectiveness of the sperm test, the sperm sample is immediately delivered to the laboratory. The sperm sample given in the laboratory is subjected to many processes and the best quality sperms are selected. The purpose of the procedures is to examine the sperm count, motility and shape in the semen and to reach quality sperm as a result.

Apart from the hospital, sperm samples can be placed in a container and brought to the hospital in the home environment. However, this is highly not recommended. Even if this is accepted, the sperm samples should be brought to the hospital and delivered within half an hour.

Issues and Precautions to Consider When Analyzing Sperm Sample



After the sperm test is given by the prospective fathers, it is examined in the laboratory environment. This examination takes approximately 1-2 hours and after the first hour, active results begin to be obtained. However, sometimes different situations can be encountered. For example, the test is given, but no sperm can be seen when looked at. In these cases, sperm are taken again and centrifuged. When faced with such a situation, the time may be extended. If there is no additional test to be done, the test results are immediately available in an average of 1-1.5 hours.

What Do Sperm Test Results Mean?



       





Sperm test results can be evaluated in many ways. Sperm analysis evaluates the sperm by analyzing it from various aspects. We can list these analyzes as follows:

· Sperm count and density:

Sperm count describes the number of sperm in 1 ml of semen. The World Health Organization advocates that a normal sperm count should be at least 15 million per ml or at least 39 million per sample. Having fewer sperm than these numbers indicates a low sperm count.

· Sperm morphology:

Non-abnormal sperm have a long tail and oval head. Morphology refers to the size and shape of the sperm a person has. Sperm that do not have a normal size or are weak in shape have difficulty reaching the egg and fertilization.

· Sperm motility:

The ability of sperm to move efficiently is one of the most important factors for fertilization.

· PH level of sperm:

When the pH level is too high or too low, it can affect the health of sperm and its ability to pass through the female reproductive tract.

Apart from these, sperm health is examined by looking at many factors such as semen volume, liquefaction, and seminal fructose levels while performing the sperm test. After examining all factors in detail, the results are examined and reported to the patient.

What is the Sperm Test Result of a Healthy Individual?



Low sperm count can have many different causes. The first reason is smoking addiction. Smoking addiction is one of the important factors that reduce the sperm count. In addition to smoking, alcohol and drug addiction also affect sperm count. Sperm count can also be adversely affected when there is a deficiency in hormones, depending on the clogged ducts.

Hormones are one of the important factors for reproduction on their own. Since the deficiency in reproductive hormones directly affects sperm production, it increases the possibility of encountering problems in reproduction. Apart from these, mistakes made by couples who want to have children also affect the sperm count. Using natural products unconsciously and continuing to use them uncontrollably, without knowing the limit, does harm to the person instead of providing benefits. Long-term treatment and drugs used during the treatment also affect the sperm count.

IMSI in Sperm Selection



The IMSI (Intracytoplasmic Morpholgically Selected Sperm Injection) method is the magnification and examination of even the smallest cells using special microscopes. In the past, in the microinjection procedures applied in IVF treatments, living sperm cells could be enlarged up to 400 times. However, with IMSI, sperm can now be enlarged between 6000 and 8000 times. It is possible to examine and detect in detail the disorders called "vacuoles" that indicate the intracellular structures of the sperm and their genetic damage.

The IMSI technique is an extremely useful method. Selected sperm injection; It allows advanced morphological analysis of sperm without damaging the living sperm cell. Sperm with the highest fertilization ability are selected and a high chance of fertilization between 20% and 40% can be obtained with the applied microinjection application.

Precautions to be Considered for Sperm Quality



Couples who want to have children should pay attention to egg and sperm health and be careful in this regard. There are many factors that affect sperm quality, such as those that affect egg quality. One of these factors is undoubtedly a healthy diet. A healthy diet is extremely important for every organ in the body, of course also in sperm health.

In addition, exercise is very important in making you more vigorous and increasing your body's stamina and activity. Regular exercise will make you recover in a short time and will positively affect both your mental and physical health. Alcohol and smoking are substances that affect reproductive cells and should be avoided. This is a proven fact as a result of research. If we gather all these under one title, we can say that one should take care of his own health. Nutrition, avoiding alcohol, smoking, exercising regularly will first affect your health and therefore your sperm quality.

This process, which is sensitive and special for couples who want to have a child, is extremely important for them. In this process, prospective parents experience excitement on the one hand and a lot of stress on the other. Hüma IVF Center, which understands the emotions experienced best and does not spare its support by being by their side throughout the process, is always ready to accompany you.

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Blastocyst transfer, which is one of the advanced in vitro fertilization techniques applied today, is a method that offers a much higher chance of pregnancy to couples who want to have children. The blastocyst transfer method, which is a method that minimizes the possibility of multiple pregnancy, which is frequently encountered in IVF treatments, supports families in making their plans to have a child more effectively. The blastocyst is defined as the 5th or 6th day of the egg becoming an embryo. Before transfer, one or two embryos of the highest quality are selected and the transfer is carried out. This method is among the most important processes of IVF treatment. What is blastocyst transfer, what are its advantages and risks? You can continue reading our article, which includes the details of blastocyst transfer with questions.


What is blastocyst transfer?



Blastocyst transfer, which has an extremely important place in the IVF treatment process, is the process of transferring the embryo created in the laboratory environment to the woman on the 5th or 6th development day. Embryos are followed in incubators in the laboratory and when they reach the blastocyst stage, transfer to the uterus is performed. Blastocyst transfer has many positive contributions to the IVF process, such as enabling better quality embryo transfer and reducing the risk of multiple pregnancy.


What are the advantages of blastocyst transfer?



Blastocyst transfer is a method that has been used frequently in recent years, depending on the developing technologies. In the first years of in vitro fertilization treatment, the expected time for transfer was 48 hours, but this period has been extended in parallel with the developments experienced today. In the blastocyst transfer method, embryos with the highest success rate are selected more easily with transfers made after 5 and 6 days. In general, the advantages of blastocyst transfer can be listed as follows;

The chance to achieve better results against recurrent pregnancy failures, thanks to the selection of embryos with better development potential and compatibility with the uterus,

Reducing the possibility of multiple pregnancy by transferring fewer embryos with high viability,

The chance to observe the embryo development more clearly and healthily,

Freezing of embryos at the time when they have the highest developmental power, that is, at the blastocyst stage,

· Allowing different methods to examine embryo viability.



What is the risk of blastocyst transfer?



The condition that can be encountered frequently as a result of blastocyst transfer is the factor of multiple pregnancy. For this reason, some legal restrictions have been imposed on the number of embryos to be transferred in order to be protected from the risks of multiple pregnancy. For our country, this limit has been determined to be a maximum of 2 embryos. By performing 1 or 2 blastocyst transfers in embryo transfer on the 5th day, both the risk of multiple pregnancy is reduced and the chance of pregnancy is increased. The aim of IVF treatment is to achieve a healthy fertilization. In this direction, better quality but less number of embryo transfers will minimize the risks that may be encountered and will facilitate healthy results.


Who is blastocyst transfer suitable for?



Blastocyst transfer can be applied to all couples with a high number of fertilized eggs and good embryo quality on the 2nd day. Since a single embryo can be transferred in the first two attempts under the age of 35, a blastocyst transfer will be made to them, thus preventing multiple pregnancy. In our country, blastocyst transfer is successfully applied and high success rates are achieved. However, the remaining quality embryos after the transfer are successfully frozen with the vitrification method, which is a new and fast freezing technique, giving couples a second chance. You can visit our website for more information and to make an appointment.

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IVF treatments are supported by a wide range of tests and analyzes to get a healthy result. With the help of these tests, problems that may occur before and after pregnancy are also detected and planning is carried out in this direction. NGS, a genetic analysis technology that allows comprehensive chromosome screening to be performed in embryos, is a test that gives extremely effective results as technological developments gain momentum. With NGS, embryos are scanned quickly and effectively, and genetic problems at the chromosome level are detected before pregnancy. The aim of this method is to select a healthy embryo by performing genetic analysis on embryos before the transfer process and to increase the chances of a healthy pregnancy. You can continue reading our article for the details of the NGS test.



What is Comprehensive Chromosome Screening (NGS)?


It is extremely important that the embryos obtained in IVF treatments are successfully transferred to the uterus. But in some cases, pregnancy may not be achieved. One of the most important reasons why a healthy pregnancy cannot be achieved despite embryo transfer in treatment has been identified as chromosome disorders that occur in embryos. In order to achieve a healthy and successful result in IVF treatments, it is necessary to analyze the embryos in detail and detect chromosomal abnormalities. Previously, the multidimensional and complex structure of chromosomes would have made multiple tests necessary. While this situation is quite time consuming and costly, the NGS (Next Generation Sequencing) test appears as a result of the developing technology today. The NGS method is a newly developed genetic analysis technology that allows comprehensive chromosome screening of embryos. The NGS method allows all embryos to be screened within a short period of time. With NGS, which offers a quick and detailed scan, chromosome-related problems are diagnosed before pregnancy. All 24 chromosomes are scanned with the NGS test.

Comprehensive chromosomal screening practices performed by the NGS method play an extremely important role in diagnosing disorders and have an effect on facilitating healthy outcomes in IVF treatments.


What are the Features of the NGS Technique?




Chromosomal abnormalities are determined by screening with the NGS method. Embryos containing more than two or more cell communities with different chromosomal structures are called “mosaic embryos”. Mosaic embryos are detected more easily with the NGS technique. After these chromosomal abnormalities detected by the NGS test are detected accurately and in detail, the process is advanced by including them in the treatment planning. Compared to the different PGD methods used to date and known, the NGS method provides a high-intensity scanning area, allowing you to detect even some genetic disorders, as well as numerical changes occurring in chromosomes.


What Genetic Defects Can Be Detected with NGS-Based PGS?



Embryos obtained in IVF treatment are evaluated according to various criteria in terms of the characteristics they have, and a healthy result is sought by ensuring the transfer of the embryo with the best developmental characteristics to the uterus. Examination of the developmental characteristics of the embryo under a microscope by classical methods does not give a clear information about the chromosomal state of the embryo. This information is only reached by performing a genetic screening with PGS. Even if the embryos have a good quality structure, they can contain various chromosomal problems, and this can also lead to problems such as early miscarriages, some structural disorders in the developing fetus, or the embryo does not hold on to the uterus. The main purpose of using the PGS method, which is an NGS-based method, is to increase the adhesion of the embryo to the uterus, which is found to have a chromosomally normal structure, to reduce the likelihood of miscarriage that may occur later, and as a result, to increase the likelihood of couples having healthy babies. The NGS-based PGS operation is performed by embryologists who have the necessary education and experience in this regard. The process takes a short time and does not cause any harm to the embryo. The PGS process begins by combining the egg taken from the expectant mother and the sperm taken from the expectant father outside the body. 5. Development of embryos from formed embryos. or 6. on the day when the blastocyst is at the stage, several cells are taken by biopsy without damaging the embryo. These received cells are sent to the genetic laboratory for a scan of 24 chromosomes, while the embryos are frozen. At this point, it is extremely important that the procedure is performed by a qualified embryologist so that the embryo does not get damaged. At the end of this examination, the embryo or embryos whose genetic structure has been determined to be healthy are transferred after completion of intrauterine preparation and pregnancy results that reach higher rates are obtained, especially.

To summarize briefly; NGS-based PGS is a genetic screening method and can be used to detect numerical and structural imbalances in chromosomes. However, single gene diseases, especially those with familial transmission, cannot be detected with the PGS method.


Who are the Groups of Patients Who Can Be Administered NGS?




The benefits of the NGS method, which is a new generation genetic analysis technology, also raises the question of which patient groups this technique can be applied to. Before answering this question, we can state that the intended point of the NGS method is to be able to detect numerical and structural changes in chromosomes. Therefore, we can address the question of which people have these changes more often for groups of patients who can be administered NGS. Groups of patients for whom NGS can be applied can be listed as follows;

· In cases of repeated miscarriage,

· in expectant mothers over the age of 38,

· In severe male infertility,

* In cases of infertility, the cause of which is unknown,

· It is applied in cycles of continuous self-recurring treatment failures.

The NGS method, which is a rapidly developing field, is actively used in many countries today due to its possibilities and facilitating and accelerating effects for the process.


What are the Advantages of Preimplantastone Genetic Screening with NGS?




NGS, a new genetic examination method used to screen for 24 chromosomes in embryos, provides the opportunity to examine and sequence the entire human genome both numerically and structurally in a short period of time, such as a single day. It offers us a revolutionary technology in this aspect. The improved NGS method can detect mosaic embryos better than other PGD methods. The main advantages of Preimplantastone Genetic Screening with NGS are that it allows you to quickly scan a large area of genes, both numerically and structurally. In addition to scanning gene fields numerically and structurally, the NGS method also has advantages such as obtaining a more accurate result with a low margin of error, achieving faster results, and having a lower cost. With this method, 24 chromosome screening can also be performed simultaneously with the study of single gene diseases and HLA typing.


Does NGS Damage the Embryo?




IVF treatments are an extremely exciting period for couples. During this period, in order to obtain a healthy result, various tests are applied to the embryos obtained to determine the success rate. In some cases, couples may have a high risk of genetically abnormal embryo development. Advanced maternal age is one of these conditions. Embryos that are not genetically normal are not suitable for transfer. In order to be able to determine the chromosomal status of embryos and to obtain a healthy result, process planning is carried out in the light of the NGS result. Another confusing situation for couples at this point is whether NGS causes any damage to the embryo during the application phase. Doctors who specialize in their field and NGS performed under appropriate conditions do not pose a danger risk to the embryo. At this point, managing and planning the process in accordance with the needs with a reliable specialist and institution will also be an extremely important step.


Does Pregnancy Always Occur With a Smoothly Detected Embryo?




After the tests and examinations, embryos that do not carry any genetic abnormalities are placed in the uterus. The probability of the occurrence of pregnancy after this procedure develops due to various factors. These factors;

· Women's age

· The amount of ovarian reserve of the woman

* Sperm quality

· Embryo quality

· Ensuring a proper intrauterine environment

· The presence of hydrosalpinx

· Conditions encountered during embryo transfer

it can be sorted as follows. All these factors are among the dec that affect the occurrence of pregnancy. From this point of view, it is impossible to say that pregnancy always occurs with an embryo that is detected without problems.

Studies have shown that age-related embryos are less likely to be chromosomally normal. For this reason, pregnancy rates are also decreasing due to the increasing age of women, especially in IVF trials that have not been applied to PGS. In women under the age of forty, NGS-based PGS normal embryos vary between 40 and 60 percent probability with the results of the analysis, the rate falls below twenty percent in people over the age of 40.

In women over the age of forty, a low pregnancy rate is achieved by transferring an embryo that has not been genetically screened with NGS, while this rate is increased by transferring an embryo that has been diagnosed with NGS and is chromosomally normal.


How Many Days Do NGS Results Come Out?



The embryos that have been biopsied are 5 or 6 until they reach the blastocyst stage. by following it up to the day, only embryos that have not been detected as abnormalities are transferred to the expectant mother's uterus (uterus). The NGS process applied to the embryos is completed within the same day. In this way, treatment planning is quickly directed.

What are the NGS Test Prices?

The information obtained from the results of the NGS test gives a comprehensive information for the IVF process. At this point, NGS, a new generation genetic screening test, has entered our lives as a result of high technology. It is a method that also has many advantages, especially if it provides a quick and wide information about the chromosomal state of the embryo. In addition to the advantages it provides, NGS is a method that also has an extremely low cost. This is a situation that also increases the availability of the test. As the Huma IVF family, we continue to be there for our couples during this exciting process. For all your questions about NGS, you can review our site and contact us for detailed information.

In this article, we have included details about the NGS method. It is important to detect embryos that do not have chromosomal abnormalities, as well as to successfully transfer the embryos obtained in IVF treatments to the uterus. Comprehensive chromosomal screening practices performed by the NGS method play an extremely effective role in detecting chromosomal disorders in embryos and increase the risk of a positive outcome of the process.

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Foods That Boost Fertility: A Nutritional Guide for IVF Patients

Embarking on an IVF journey can be both exciting and overwhelming. While medical advancements have significantly increased the chances of conception, diet plays a crucial role in supporting reproductive health and improving IVF success rates. A well-balanced diet rich in essential nutrients can enhance fertility, regulate hormones, and improve overall well-being. In this guide, we will explore the best fertility-boosting foods for IVF patients.

1. The Role of Nutrition in IVF Success

Nutrition has a direct impact on reproductive health. A diet rich in antioxidants, healthy fats, vitamins, and minerals can improve egg quality, support embryo development, and enhance uterine health. Conversely, unhealthy eating habits, excessive processed foods, and trans fats may negatively affect fertility.

2. Fertility-Boosting Foods for IVF Patients

A. Antioxidant-Rich Foods

Antioxidants help reduce oxidative stress, which can damage egg and sperm cells. Incorporate these antioxidant-rich foods into your diet:

  • Berries (strawberries, blueberries, raspberries) – High in vitamin C and folate.

  • Dark leafy greens (spinach, kale, Swiss chard) – Loaded with folic acid and iron.

  • Nuts and seeds (walnuts, almonds, flaxseeds, chia seeds) – Contain vitamin E and selenium, crucial for reproductive health.

  • Dark chocolate (with at least 70% cocoa) – Rich in flavonoids that support blood circulation to reproductive organs.

B. Healthy Fats

Healthy fats are essential for hormone production and egg quality. Opt for:

  • Avocados – A great source of monounsaturated fats that promote hormone balance.

  • Olive oil – Anti-inflammatory properties support embryo implantation.

  • Fatty fish (salmon, sardines, mackerel) – Rich in omega-3 fatty acids, crucial for reproductive health.

  • Nuts and seeds – Provide healthy fats and essential micronutrients.

C. Protein Sources

Protein is vital for cell development and hormone production. Prioritize:

  • Lean meats (chicken, turkey, lean beef) – Provide high-quality protein and iron.

  • Eggs – Contain choline and vitamin D, essential for fertility.

  • Legumes (lentils, chickpeas, beans) – Plant-based proteins that boost hormonal balance.

  • Greek yogurt – A probiotic-rich dairy option that supports gut health and nutrient absorption.

D. Whole Grains

Whole grains provide sustained energy and improve insulin sensitivity, which is crucial for reproductive health. Include:

  • Quinoa – A gluten-free, protein-rich grain with essential amino acids.

  • Brown rice – Supports blood sugar balance and ovulation.

  • Oats – High in fiber, promoting digestive health and hormonal balance.

  • Whole wheat bread – Provides essential B vitamins for reproductive function.

E. Hydration and IVF Success

Proper hydration is key to reproductive health. Drinking enough water helps maintain cervical mucus, improves egg health, and enhances nutrient absorption. Aim for at least 8-10 glasses of water daily, and include herbal teas like ginger or peppermint for additional benefits.

3. Foods to Avoid During IVF Treatment

Certain foods can negatively impact fertility and IVF success. Limit or avoid:

  • Processed foods – High in trans fats and artificial additives that disrupt hormonal balance.

  • Excess caffeine – May reduce fertility and interfere with implantation.

  • Sugary foods and beverages – Can cause insulin spikes, affecting ovulation.

  • Alcohol – Lowers fertility rates and negatively impacts egg and sperm quality.

  • Soy-based products – Excessive soy can disrupt estrogen levels.

4. Final Tips for a Fertility-Boosting Diet

  • Follow the Mediterranean diet – This diet, rich in whole foods, healthy fats, and lean proteins, is linked to improved IVF success rates.

  • Maintain a balanced meal plan – Aim for variety and include a mix of macronutrients.

  • Consult a nutritionist – If needed, seek guidance for a personalized diet plan.

  • Stay active and manage stress – Regular physical activity and stress reduction techniques, such as yoga or meditation, can further support fertility.

Conclusion

A fertility-focused diet can significantly enhance IVF success rates by improving egg quality, regulating hormones, and creating an optimal environment for conception. By incorporating nutrient-dense foods and avoiding fertility-disrupting substances, you can support your journey toward parenthood. Always consult with your fertility specialist or nutritionist to tailor a diet plan suited to your specific needs.

Are you ready to take charge of your IVF journey through nutrition? Start today by making small, healthy changes that will benefit your reproductive health and overall well-being!

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How to Improve Egg Productivity & Quality

Fertility is a crucial aspect of reproductive health, and for women, egg productivity and quality play a vital role in conception. The number and quality of eggs naturally decline with age, but various lifestyle changes, diet improvements, and medical interventions can help maintain and enhance ovarian health. Whether you are planning for pregnancy now or preserving fertility for the future, here are some effective ways to boost egg productivity and quality.

1. Maintain a Balanced and Nutrient-Rich Diet

What you eat directly impacts your reproductive health. A fertility-friendly diet should include:

  • Antioxidants: Found in berries, nuts, and leafy greens, antioxidants help protect eggs from oxidative stress.

  • Healthy Fats: Avocados, olive oil, and nuts support hormonal balance and egg cell membrane integrity.

  • Protein Sources: Include lean meats, fish, eggs, and plant-based proteins like beans and lentils to promote healthy egg development.

  • Folic Acid & B Vitamins: Essential for cell division and DNA synthesis. Found in leafy greens, citrus fruits, and fortified grains.

  • Omega-3 Fatty Acids: Found in salmon, flaxseeds, and walnuts, they enhance egg quality and overall reproductive health.

2. Stay Hydrated

Drinking enough water is essential for circulation and nutrient transport to the ovaries. Dehydration can negatively affect egg development and hormone production.

3. Maintain a Healthy Weight

Being overweight or underweight can disrupt hormonal balance and ovulation. Maintaining a BMI within a healthy range supports regular ovulation and egg maturation.

4. Reduce Stress Levels

Chronic stress increases cortisol levels, which can interfere with reproductive hormones and egg development. Stress management techniques include:

  • Meditation & Yoga: Help regulate stress hormones and improve blood flow to reproductive organs.

  • Regular Exercise: Moderate physical activity boosts circulation and hormone regulation.

  • Adequate Sleep: 7-9 hours of quality sleep each night supports hormone balance and overall health.

5. Avoid Toxins and Harmful Substances

  • Reduce Caffeine & Alcohol: Excessive intake can negatively affect fertility.

  • Quit Smoking: Smoking accelerates ovarian aging and reduces egg quality.

  • Limit Exposure to Environmental Toxins: Pesticides, plastics (BPA), and heavy metals can harm egg health. Opt for organic foods and use BPA-free products.

6. Take Fertility-Boosting Supplements

Certain vitamins and supplements can enhance egg quality:

  • Coenzyme Q10 (CoQ10): Improves egg cell energy and mitochondrial function.

  • Vitamin D: Supports ovarian function and hormonal balance.

  • Zinc & Selenium: Help protect eggs from oxidative stress and improve overall reproductive health.

  • DHEA (Dehydroepiandrosterone): A precursor hormone that can help improve ovarian reserve in some cases (consult a doctor before use).

7. Consider Medical Interventions if Necessary

If you are struggling with fertility issues, consult a specialist who may recommend:

  • Hormonal Therapy: Helps regulate ovulation and improve egg development.

  • Ovulation Induction Medications: Clomiphene citrate or Letrozole can stimulate egg production.

  • IVF (In Vitro Fertilization): If natural conception is difficult, IVF can retrieve multiple eggs for fertilization.

  • PRP (Platelet-Rich Plasma) Therapy: An emerging treatment that may help rejuvenate ovarian function.

8. Monitor Your Ovarian Reserve

Regular fertility check-ups can help assess egg quality and quantity. Tests such as:

  • AMH (Anti-Müllerian Hormone) Test: Measures ovarian reserve.

  • FSH & Estradiol Tests: Assess ovarian function and hormone levels.

  • Antral Follicle Count (AFC) via Ultrasound: Provides insights into egg supply.

Conclusion

Improving egg productivity and quality requires a holistic approach that includes a healthy diet, lifestyle adjustments, and, if needed, medical assistance. By adopting these strategies, you can enhance your fertility potential and increase your chances of a successful pregnancy. If you are planning for the future, consider consulting a fertility specialist for personalized guidance on preserving and optimizing your reproductive health.

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Best Sleeping Practices for Newborns: How to Ensure Safe Sleep

Newborns spend most of their early days sleeping, making it essential for parents to create a safe and comfortable sleep environment. Following best sleep practices not only helps your baby rest better but also reduces the risk of Sudden Infant Death Syndrome (SIDS) and other sleep-related concerns. Here’s a comprehensive guide to ensuring safe sleep for your newborn.

1. Follow the "Back to Sleep" Rule

One of the most crucial sleep safety tips is placing your baby on their back to sleep, both for naps and nighttime rest. This reduces the risk of SIDS significantly. Avoid placing your baby on their stomach or side, as these positions can obstruct breathing.

2. Choose a Safe Sleeping Surface

  • Use a firm, flat mattress covered with a fitted sheet in a safety-approved crib or bassinet.

  • Avoid placing soft bedding, pillows, stuffed animals, or crib bumpers in the sleeping area, as these increase the risk of suffocation.

  • Do not let your baby sleep on couches, armchairs, or adult beds unattended.

3. Keep the Crib in Your Room

  • The safest place for a newborn to sleep is in a crib or bassinet in the same room as the parents (but not in the same bed) for at least the first six months.

  • Room-sharing reduces the risk of SIDS and makes nighttime feedings easier.

4. Regulate Room Temperature

  • Keep the room at a comfortable temperature (between 20-22°C or 68-72°F).

  • Overheating increases SIDS risk, so dress your baby in light, breathable layers rather than heavy blankets.

5. Avoid Loose Blankets – Use a Sleep Sack

  • Instead of blankets, use a sleep sack or swaddle to keep your baby warm.

  • If swaddling, ensure the baby’s hips can move freely to prevent hip dysplasia.

6. Follow a Consistent Sleep Routine

  • Establish a simple bedtime routine with activities like bathing, feeding, gentle rocking, or soft lullabies to help your baby recognize sleep time.

  • Newborns thrive on predictability, so keeping a consistent routine helps improve sleep quality.

7. Offer a Pacifier at Bedtime

  • Giving your baby a pacifier during sleep times may help reduce SIDS risk.

  • If breastfeeding, wait 3-4 weeks until breastfeeding is well established before introducing a pacifier.

8. Avoid Smoking and Exposure to Secondhand Smoke

  • Secondhand smoke increases the risk of SIDS and other respiratory issues.

  • Keep your baby in a smoke-free environment at all times.

9. Be Mindful of Daytime and Nighttime Sleep Differences

  • Encourage daytime alertness by exposing your baby to natural light and engaging in play.

  • Keep nighttime interactions quiet and calm, with dim lighting, to reinforce that night is for sleep.

10. Know When to Seek Medical Advice

  • If your baby struggles to breathe, has irregular sleep patterns, or seems excessively fussy, consult a pediatrician.

  • Regular check-ups ensure your newborn is developing healthily and sleeping well.

Conclusion

Creating a safe sleep environment for your newborn is essential for their well-being and your peace of mind. By following these best sleeping practices, you can help your baby sleep soundly and safely. If you have concerns about your baby's sleep habits, always consult your pediatrician for guidance.

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