Last Update Date
15.2.2024
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Sperm Selection (IMSI)
In cases of male infertility, where sperm cells cannot reach the female egg for any reason or cannot cross the egg membrane, a new IVF method, the microinjection technique, is used. Before the advent of this technique, the effectiveness of drug treatments and varicocele surgeries used in cases of severe male infertility has never been clearly established. Currently, experts say that these treatments have no place in cases of severe male infertility and should no longer be used.

The microinjection technique applied in these cases has clearly changed the fate of these men. For the first time, the treatment of these conditions is carried out at the cell level. A single sperm cell is injected into the egg obtained from a woman under a microscope with the help of a needle thinner than a hair shaft and fertilization is achieved.

This technique mainly addresses three different categories of disorders. These are cases where sperm count or motility is missing, or cases where sperm shapes (morphology) are impaired. In microinjection applications, the fertilization rate is not related to the sperm rate. Even in cases where there are several sperm cells in the semen, the fertilization rate does not change (70 - 80%). With this technique, pregnancy can be achieved even with a few sperm cells.

In cases where the mobility of sperm cells is insufficient, this technique can be used to solve the difficulty of spermatozoa to cross the egg membrane. It has been known for many years that sperm shape disorder is a cause of infertility, even in in vitro fertilization applications performed in these cases, there is no fertilization or the fertilization rate is very low.

In microinjection technique applications, sperm shapes do not have a negative effect on fertilization and pregnancy rates. The egg is sucked with the help of a tube (pipette) and fixed. Sperm is injected into the egg with a thin glass needle. Two days later, the fertilized egg (embryo) is inserted into the uterus.
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